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Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) Peptide

TNFSF12 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN940372
$398.38
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 16 to 22 Business Days

Quick Overview for Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) Peptide (ABIN940372)

Target

TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

Origin

Mammalian

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    LGLLLAVVSL GSRASLSAQE PAQEELVAEE DQDPSELNPQ TEESQDPAPF

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of TNFSF12 antibody,
    Alternative Names: TNFSF12 control peptide, TNFSF12 antibody Blocking Peptide, Anti-TNFSF12 Blocking Peptide, Tumor Necrosis Factor Superfamily 12 Blocking Peptide, APO3L Blocking Peptide, DR3LG Blocking Peptide, MGC129581 Blocking Peptide, MGC20669 Blocking Peptide, TWEAK Blocking Peptide, TNFSF12, TNFSF-12, TNFSF 12, TNFSF-12 Blocking Peptide, TNFSF 12 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

    Background

    TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.

    Molecular Weight

    17 kDa
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