Browse our Raptor Proteins (RPTOR)

Full name:
Regulatory Associated Protein of MTOR, Complex 1 Proteins (RPTOR)
On are 3 Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) Proteins from 2 different suppliers available. Additionally we are shipping Raptor Antibodies (82) and Raptor Kits (7) and many more products for this protein. A total of 95 Raptor products are currently listed.
4320, 4932417H02Rik, CG4320, DDBDRAFT_0191024, DDBDRAFT_0234064, DDB_0191024, DDB_0234064, Dmel\\CG4320, dRap, dRaptor, KOG1, Mip1, mKIAA1303, Rap, raptor, raptor/CG4320, RGD1311784
list all proteins Gene Name GeneID UniProt
Rat RPTOR RPTOR 287871  
RPTOR 57521 Q8N122
RPTOR 74370  

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Raptor Proteins (RPTOR) by Origin

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More Proteins for Raptor Interaction Partners

Fruit Fly (Drosophila melanogaster) Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) interaction partners

  1. We found that neither S6K-dependent cell growth nor S6K-Thr-398 phosphorylation was affected in rictor-null mutants.

Human Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) interaction partners

  1. Data show that mTOR (show FRAP1 Proteins) protein forms a complex with Raptor and estrogen receptor-alpha (ERalpha (show ESR1 Proteins)).

  2. Up-regulation of mTORC1 via raptor by aldosterone is a critical pathobiologic mechanism that controls pulmonary artery smooth muscle cell survival to promote hypertrophic vascular remodeling and pulmonary arterial hypertension.

  3. Hgh mTOR (show FRAP1 Proteins) activity and Rictor overexpression could be markers of a bad prognosis. Combined phosphoprotein and Rictor/Raptor expression evaluation revealed even stronger statistical correlation with prognosis.

  4. revealed more than 170 NFAT (show NFATC1 Proteins)-associated proteins, half of which are involved in transcriptional regulation. Among them are many hitherto unknown interaction partners of NFATc1 (show NFATC1 Proteins) and NFATc2 (show NFAT1 Proteins) in T cells, such as Raptor, CHEK1 (show CHEK1 Proteins), CREB1 (show CREB1 Proteins), RUNX1 (show RUNX1 Proteins), SATB1 (show SATB1 Proteins), Ikaros (show IKZF1 Proteins), and Helios (show ZNFN1A2 Proteins).

  5. In this study we began by validating the expression of four main mTOR (show FRAP1 Proteins) pathway components, mTOR (show FRAP1 Proteins), DEPTOR (show DEPTOR Proteins), rictor and raptor, at gene and protein level in in vitro models of endometrioid (MDAH2774) and clear cell (SKOV3) ovarian cancer

  6. Our results demonstrate for the first time that the expression quantitative trait loci of RPTOR, rs7502563, is susceptible to glioma

  7. The positive regulation of mTORC1 activity by NPRL2 (show NPRL2 Proteins) is mediated through NPRL2 (show NPRL2 Proteins) interaction with Raptor.

  8. Propose regulation of placental SNAT2 (show SLC38A2 Proteins)/LAT1 (show LAT Proteins) ubiquitination by mTORC1 and Nedd4-2 (show NEDD4L Proteins).

  9. RPTOR was not associated with bipolar disorder or schizophrenia.

  10. microRNA-210 and raptor are involved in mithramycin-mediated erythroid differentiation of K562 cells and participate to the fine-tuning and control of gamma-globin gene expression in erythroid precursor cells.

Mouse (Murine) Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) interaction partners

  1. mitochondrial dysfunction triggers LKB1 (show STK11 Proteins)-mediated AMPK (show PRKAA1 Proteins) activation, which stimulates Sirt2 (show SIRT2 Proteins) phosphorylation, leading to activation of mTOR (show FRAP1 Proteins)-RAPTOR and Glut1 (show SLC2A1 Proteins)-mediated glucose uptake.

  2. inhibiting regulatory-associated protein of mechanistic target of rapamycin (show FRAP1 Proteins) (RPTOR) in hyperoxia settings, limited lung injury by increased autophagy, decreased apoptosis, improved lung architecture, and increased survival.

  3. Raptor knockout mice are lean and insulin (show INS Proteins) resistant with increased energy expenditure, and they are resistant to a high-fat diet.

  4. The findings reveal HDAC5 (show HDAC5 Proteins)-mTORC1 signaling as a novel mechanism in the differential regulation of gastric ghrelin (show GHRL Proteins) and nesfatin-1 (show NUCB2 Proteins).

  5. data suggest that EtOH-induced decreases in protein synthesis in fasted mice may be independent of mTORC1 and MAPK (show MAPK1 Proteins) signaling.

  6. Raptor negatively regulates hepatic Akt (show AKT1 Proteins) activity and lipogenesis via PHLPP2 (show PHLPP2 Proteins) stabilization.

  7. mTOR (show FRAP1 Proteins) kinase-dependent, but raptor-independent regulation of downstream signaling is important for myogenic differentiation.

  8. conditional gene ablation of raptor causes delayed myelination initiation as well as hypomyelination, together with abnormal lipid composition and decreased nerve conduction velocity.

  9. Rptor deficiency/mTORC1 Signaling in oocytes are dispensable for the survival of primordial follicles and for female fertility.

  10. Raptor ablation in skeletal muscle decreases Cav1.1 (show CACNA1S Proteins) expression and affects the function of the excitation-contraction coupling supramolecular complex.

Raptor (RPTOR) Protein Profile

Protein Summary

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Raptor (RPTOR)

  • CG4320 gene product from transcript CG4320-RB (raptor)
  • regulatory associated protein of MTOR, complex 1 (Rptor)
  • regulatory associated protein of MTOR, complex 1 (RPTOR)
  • regulatory associated protein of MTOR, complex 1 (rptor)
  • HEAT repeat-containing protein (raptor)
  • 4320 protein
  • 4932417H02Rik protein
  • CG4320 protein
  • DDBDRAFT_0191024 protein
  • DDBDRAFT_0234064 protein
  • DDB_0191024 protein
  • DDB_0234064 protein
  • Dmel\\CG4320 protein
  • dRap protein
  • dRaptor protein
  • KOG1 protein
  • Mip1 protein
  • mKIAA1303 protein
  • Rap protein
  • raptor protein
  • raptor/CG4320 protein
  • RGD1311784 protein

Protein level used designations for RPTOR

CG4320-PB , dRaptor , raptor-PB , target of rapamycin (TOR)-associated protein , raptor , Raptor family protein , WD40 repeat-containing protein , armadillo-like helical domain-containing protein , p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats , regulatory-associated protein of mTOR , p150 target of rapamycin (TOR)-scaffold protein

31543 Drosophila melanogaster
287871 Rattus norvegicus
454949 Pan troglodytes
495002 Xenopus laevis
8617737 Dictyostelium discoideum AX4
100170605 Xenopus (Silurana) tropicalis
57521 Homo sapiens
74370 Mus musculus
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