This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011].
Chu, Awasthi, White, Chrzanowska-Wodnicka, Malarkannan: "Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3373-83, (2008) (PubMed).
Aliases for RAP1B Proteins
RAP1B, member of RAS oncogene family (RAP1B) Proteins RAP1B, member of RAS oncogene family (Rap1b) Proteins RAP1B, member of RAS oncogene family L homeolog (rap1b.L) Proteins RAP1B, member of RAS oncogene family (Bm1_39445) Proteins RAS related protein 1b (Rap1b) Proteins ras-related protein Rap-1b-like (LOC109067672) Proteins RAP1B, member of RAS oncogene family (rap1b) Proteins 2810443E11Rik Proteins cb119 Proteins cb1026 Proteins K-REV Proteins k-rev Proteins RAL1B Proteins ral1b Proteins Rap1b Proteins sb:cb119 Proteins wu:fb11c04 Proteins wu:fb74e09 Proteins wu:fk70e05 Proteins