Browse our anti-TNFRSF14 (TNFRSF14) Antibodies

Full name:
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 Antibodies (TNFRSF14)
On www.antibodies-online.com are 186 Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) Antibodies from 31 different suppliers available. Additionally we are shipping TNFRSF14 Proteins (33) and TNFRSF14 Kits (13) and many more products for this protein. A total of 253 TNFRSF14 products are currently listed.
Synonyms:
Atar, CD270, HveA, Hvem, LIGHTR, Tnfrs14, TR2
list all antibodies Gene Name GeneID UniProt
TNFRSF14 366518  
TNFRSF14 8764 Q92956
TNFRSF14 230979  

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Top referenced anti-TNFRSF14 Antibodies

  1. Human Polyclonal TNFRSF14 Primary Antibody for WB - ABIN265160 : Watts: TNF/TNFR family members in costimulation of T cell responses. in Annual review of immunology 2005 (PubMed)
    Show all 5 references for 265160

  2. Human Monoclonal TNFRSF14 Primary Antibody for FACS, IF - ABIN180391 : Kwon, Tan, Ni, Oh, Lee, Kim, Kim, Wang, Gentz, Yu, Harrop, Lyn, Silverman, Porter, Truneh, Young: A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for 180391

  3. Human Polyclonal TNFRSF14 Primary Antibody for ICC, ELISA - ABIN1002432 : Marsters, Ayres, Skubatch, Gray, Rothe, Ashkenazi et al.: Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB ... in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for 1002432

  4. Human Monoclonal TNFRSF14 Primary Antibody for FACS - ABIN4897515 : Wang, Wen, Routy, Bernard, Sekaly, Watts et al.: 4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T ... in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 3 references for 4897515

  5. Human Monoclonal TNFRSF14 Primary Antibody for ELISA (Capture), FACS - ABIN4900305 : Kang, Kim, Kang, Han, Nam, Kyung, Park, Kim: LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes. in Arthritis and rheumatism 2007 (PubMed)
    Show all 3 references for 4900305

  6. Human Polyclonal TNFRSF14 Primary Antibody for ELISA, WB - ABIN250845 : Cheung, Humphreys, Potter, Norris, Shumway, Tran, Patterson, Jean-Jacques, Yoon, Spear, Murphy, Lurain, Benedict, Ware: Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  7. Human Polyclonal TNFRSF14 Primary Antibody for FACS, IHC (p) - ABIN653038 : Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: Multiple common variants for celiac disease influencing immune gene expression. ... in Nature genetics 2010 (PubMed)

More Antibodies against TNFRSF14 Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) interaction partners

  1. HIV-1 produced from CD4 (show CD4 Antibodies)+ T cells bears HSV-2 receptor HVEM and can bind to and enter HSV-2-infected epithelial cells depending on HVEM-gD interaction and the presence of gB/gH/gL.

  2. HVEM is highly expressed in ovarian serous adenocarcinoma tissues and correlated with the patient clinicopathological features.

  3. TNFRSF14 and MAP2K1 (show MAP2K1 Antibodies) mutations are the most frequent genetic alterations found in pediatric-type follicular lymphoma (PTFL) and occur independently in most cases, suggesting that both mutations might play an important role in PTFL lymphomagenesis.

  4. genetic landscape of Pediatric-type follicular lymphoma suggests that TNFRSF14 mutations accompanied by copy-number neutral loss of heterozygosity of the 1p36 locus in over 70% of mutated cases, as additional selection mechanism, might play a key role in the pathogenesis of this disease.

  5. The increased immune-stimulatory capacity of lymphoma B cells with TNFRSF14 aberrations had clinical relevance, associating with higher incidence of acute GVHD in patients undergoing allogeneic hematopoietic stem cell transplantation.

  6. These results suggest that TNFRSF14 mutations point towards a diagnosis of follicular lymphomas , and can be used in the sometimes difficult distinction between marginal zone lymphomas and follicular lymphomas

  7. the overexpression of HVEM in ovarian cancer cells may suppress the proliferation and immune function of T cells, thus leading to the development of ovarian cancer. The current study partially explains the immune escape mechanism of ovarian cancer cells.

  8. In eight cases (42%) we observed recurrent copy number loss of chr1:2,352,236-4,574,271, a region containing the candidate tumor suppressor TNFRSF14.

  9. Study report the crystal structure of unbound HVEM, which further contributes to the understanding of the molecular mechanisms controlling recognition between HVEM and its ligands.

  10. HVEM may play a critical role in tumor progression and immune evasion

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) interaction partners

  1. Dendritic cells require BTLA (show BTLA Antibodies) and HVEM to actively adjust tolerizing T cell responses under steady-state conditions.

  2. we identified herpes virus entry mediator as a functional receptor that mediates SALM5 (show LRFN5 Antibodies)'s suppressive function. Our findings reveal a molecular link between the neuronal system and the immune system, and provide potential therapeutic targets for the control of CNS diseases.

  3. results have revealed a novel role of HVEM on the regulation of IFN-I and immunopathology during Listeria infection.

  4. our studies revealed a novel function of the HVEM cosignaling molecule and its ligands in EAU pathogenesis through the induction of Th1 (show HAND1 Antibodies)- and Th17-type T cell responses

  5. Together, these data indicate that HVEM contributes to ocular pathogenesis independently of entry and point to an immunomodulatory role for this protein specifically on radiation-resistant cells.

  6. results demonstrate a role for both nectin-1 (show PVRL1 Antibodies) and HVEM as receptors and suggest a further receptor which appears much less efficient.

  7. Authors show that CD4 (show CD4 Antibodies)(+) FoxP3 (show FOXP3 Antibodies)(+) Tregs up- regulate HVEM (herpes virus entry mediator), which is a binding site for major viral glycoprotein gD, following herpes simplex virus 1 infection.

  8. results support a model whereby BTLA (show BTLA Antibodies) on innate leukocytes is triggered by HVEM and delivers negative signals into BTLA (show BTLA Antibodies)(+) cells, thereby interfering with the protective immune response to this intestinal parasite.

  9. In summary, herpes simplex virus 1 entry into epidermis was shown to strongly depend on the presence of nectin-1 (show PVRL1 Antibodies), but the restricted presence of HVEM can potentially replace nectin-1 (show PVRL1 Antibodies) as a receptor.

  10. One mechanism by which the herpes simplex virus 1 latency-associated transcript enhances latency and reactivation appears to be by upregulating HVEM expression.

TNFRSF14 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.

Alternative names and synonyms associated with TNFRSF14

  • tumor necrosis factor receptor superfamily, member 14 (Tnfrsf14) antibody
  • tumor necrosis factor receptor superfamily, member 14 (TNFRSF14) antibody
  • tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (Tnfrsf14) antibody
  • Atar antibody
  • CD270 antibody
  • HveA antibody
  • Hvem antibody
  • LIGHTR antibody
  • Tnfrs14 antibody
  • TR2 antibody

Protein level used designations for TNFRSF14

tumor necrosis factor receptor superfamily member 14 , tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) , herpesvirus entry mediator A , CD40-like protein , herpes virus entry mediator A , tumor necrosis factor receptor-like 2 , tumor necrosis factor receptor-like gene2 , herpes virus entry mediator

GENE ID SPECIES
366518 Rattus norvegicus
457221 Pan troglodytes
695042 Macaca mulatta
8764 Homo sapiens
479580 Canis lupus familiaris
230979 Mus musculus
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