HVEM antibody (AA 39-202)

Catalog No. ABIN7092932

The Rabbit Monoclonal anti-HVEM antibody (Clone DM131) (ABIN7092932) specifically detects HVEM in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for HVEM antibody (AA 39-202) (ABIN7092932)

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HVEM antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: DM131

Product Details anti-HVEM Antibody

Binding Specificity: AA 39-202

Purpose: Anti-HVEM antibody(DM131), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human HVEM(Leu39-Val202) (ABIN6964089) produced by using human HEK293 cells

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for HVEM

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Alternative Name: HVEM

Background: Synonyms:ATAR, CD270, HVEA, HVEM, LIGHTR, TR2
Description:This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.

Molecular Weight: 18.2 kDa

Gene ID: 8764

UniProt: Q92956

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints