Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HVEM Products

(Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Categories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured HVEM Categories

HVEM Antibodies

High quality antibodies with extensive validation data.

HVEM ELISA Kits

Reliable ELISA kits for a wide range of species.

HVEM Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HVEM Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (p), ELISA, WB
Validations
  • (5)
Cat. No. ABIN563772
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, IHC, WB
Validations
  • (3)
Cat. No. ABIN6655863
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, WB
Validations
  • (3)
Cat. No. ABIN6655349
Quantity 100 μg
Datasheet Datasheet

Recommended HVEM ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970979
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1889390
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1889391
Quantity 96 tests
Datasheet Datasheet

Recommended HVEM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7274832
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN6964089
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN4949111
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HVEM products

Szymczak, Ziętkiewicz, Kuncewicz, Rodziewicz-Motowidło, Orlikowska: "Expression, purification, and efficient refolding of the extracellular domain of Escherichia coli-expressed signaling receptor herpesvirus entry mediator." in: Protein expression and purification, Vol. 164, pp. 105450, (2019) (PubMed).

Kuncewicz, Spodzieja, Sieradzan, Karczyńska, Dąbrowska, Dadlez, Speiser, Derre, Rodziewicz-Motowidło: "A structural model of the immune checkpoint CD160-HVEM complex derived from HDX-mass spectrometry and molecular modeling." in: Oncotarget, Vol. 10, Issue 4, pp. 536-550, (2019) (PubMed).

Abadpour, Halvorsen, Sahraoui, Korsgren, Aukrust, Scholz: "Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT." in: Journal of molecular endocrinology, Vol. 60, Issue 3, pp. 171-183, (2018) (PubMed).

de Mare-Bredemeijer, Shi, Mancham, van Gent, van der Heide-Mulder, de Boer, Heemskerk, de Jonge, van der Laan, Metselaar, Kwekkeboom: "Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 4, pp. 1838-48, (2015) (PubMed).

Connor, Felder, Kapur, Onujiogu: "DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1." in: BMC cancer, Vol. 12, pp. 176, (2012) (PubMed).

Cheung, Oborne, Steinberg, Macauley, Fukuyama, Sanjo, DSouza, Norris, Pfeffer, Murphy, Kronenberg, Spear, Ware: "T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7286-96, (2009) (PubMed).

Wang, Wen, Routy, Bernard, Sekaly, Watts et al.: "4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8252-63, (2007) (PubMed).

Kang, Kim, Kang, Han, Nam, Kyung, Park, Kim: "LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes." in: Arthritis and rheumatism, Vol. 56, Issue 4, pp. 1106-17, (2007) (PubMed).

Watts: "TNF/TNFR family members in costimulation of T cell responses." in: Annual review of immunology, Vol. 23, pp. 23-68, (2005) (PubMed).

Cheung, Humphreys, Potter, Norris, Shumway, Tran, Patterson, Jean-Jacques, Yoon, Spear, Murphy, Lurain, Benedict, Ware: "Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13218-23, (2005) (PubMed).

Synonyms and alternative names related to HVEM

TNF receptor superfamily member 14 (Tnfrsf14), TNF receptor superfamily member 14 (TNFRSF14), tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (Tnfrsf14), ATAR, Atar, CD270, HVEA, HveA, HVEM, Hvem, LIGHTR, Tnfrs14, TR2

Protein level used designations for HVEM

  • tumor necrosis factor receptor superfamily member 14
  • tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
  • herpesvirus entry mediator A
  • CD40-like protein
  • herpes virus entry mediator A
  • tumor necrosis factor receptor-like 2
  • tumor necrosis factor receptor-like gene2
  • herpes virus entry mediator
You are here:
Support