NDM-1 Protein (AA 88-146, partial) (His tag)

Catalog No. ABIN7479627

Recombinant NDM-1 protein expressed in Escherichia coli (E. coli) and has been mentioned in 1 publication.

Quick Overview for NDM-1 Protein (AA 88-146, partial) (His tag) (ABIN7479627)

Target: NDM-1 (Metallo-beta-Lactamase (NDM-1))

Protein Type: Recombinant

Origin: Bacteria

Source: Escherichia coli (E. coli)

Application: ELISA, Western Blotting (WB)

Purity: 90 %

Product Details

Protein Characteristics: AA 88-146, partial

Purification tag / Conjugate: This NDM-1 protein is labelled with His tag.

Sequence: AANGWVEPAT APNFGPLKVF YPGPGHTSDN ITVGIDGTDI AFGGCLIKDS KAKSLGNLG

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS buffer

Storage: 4 °C

References

Chandar, Poovitha, Ilango, MohanKumar, Parani: "Inhibition of New Delhi Metallo-β-Lactamase 1 (NDM-1) Producing Escherichia coli IR-6 by Selected Plant Extracts and Their Synergistic Actions with Antibiotics." in: Frontiers in microbiology, Vol. 8, pp. 1580, (2018) (PubMed).

Target Details

Target: NDM-1 (Metallo-beta-Lactamase (NDM-1))

Background: Background: Enterobacteriaceae carrying this gene (identified by PCR) have been isolated in Sweden, India, Pakistan, Bangladesh, England, Scotland, Northern Ireland, Australia and the USA. The organisms they were identified in were K.pneumoniae, Enterobacter cloacae, E.coli, Proteus spp, Citrobacter freundii, Morganella morganii, Providencia spp and Klebsille oxytoca. In India most isolates were from community-acquired infections rather than hospital-acquired infections, indicating the gene is widespread in the environment.Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.

Molecular Weight: 10.1 kD

UniProt: F8UNN7