Osteopontin Protein (AA 17-314) (His tag)

Catalog No. ABIN620961

Recombinant Osteopontin protein expressed in not_set.

Quick Overview for Osteopontin Protein (AA 17-314) (His tag) (ABIN620961)

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Protein Type: Recombinant

Origin: Human

Host: Please inquire

Purity: > 90.0 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 17-314

Purification tag / Conjugate: This Osteopontin protein is labelled with His tag.

Sequence: MGSSHHHHHH SSGLVPRGSH RSMIPVKQAD SGSSEEKQLY NKYPDAVATW LNPDPSQKQN LLAPQNAVSS EETNDFKQET LPSKSNESHD HMDDMDDEDD DDHVDSQDSI DSNDSDDVDD TDDSHQSDES HHSDESDELV TDFPTDLPAT EVFTPVVPTV DTYDGRGDSV VYGLRSKSKK FRRPDIQYPD ATDEDITSHM ESEELNGAYK AIPVAQDLNA PSDWDSRGKD SYETSQLDDQ SAETHSHKQS RLYKRKANDE SNEHSDVIDS QELSKVSREF HSHEFHSHED MLVVDPKSKE EDKHLKFRIS HELDSASSEV N.

Characteristics: Recombinant Human Osteopontin

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Osteopontin is supplied in 20mM Tris-HCL buffer pH-7.5, 1mM DTT, 2mM EDTA and 10% glycerol.

Storage: 4 °C

Target Details

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Alternative Name: Osteopontin

Background: Secreted Phosphoprotein-1 Human Recombinant produced in E. coli is single, a non-glycosylated, Polypeptide chain containing 321 AA fragment (17-314) and having a total molecular mass of 36.2 kDa. The SPP1 protein is fused to 20 AA His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: Osteopontin is a glycoprotein that was first identified in osteoblasts and is involved in bone remodeling, immune functions in fibroblasts, macrophages, and lymphocytes during inflammation and wound healing. SPP1 binds tightly to hydroxyapatite. SPP1 forms an integral part of the mineralized matrix. SPP1 is vital to cell-matrix interaction. Secreted Phosphoprotein-1 protects against cardiac ischemia-reperfusion injury via late preconditioning. Expression of both Ostepontin and CD44 in hepatocellular carcinoma is linked with advanced tumor stage and contributes to prognosis information. SPP1 is the most over-expressed gene in intrahepatic cholangiocarcinoma. Secreted Phosphoprotein-1 overexpression is related with interstitial lung diseases. Synonyms: Secreted Phosphoprotein-1, OPN, BNSP, BSPI, ETA-1, MGC110940, SPP-1, Osteopontin, Bone sialoprotein 1, Urinary stone protein, Nephropontin, Uropontin, SPP1.

Pathways: Regulation of Cell Size