FABP1 Protein (AA 1-127) (His tag)

Catalog No. ABIN666641

This Recombinant FABP1 protein is produced in Escherichia coli (E. coli).

Quick Overview for FABP1 Protein (AA 1-127) (His tag) (ABIN666641)

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 %

Product Details

Protein Characteristics: AA 1-127

Purification tag / Conjugate: This FABP1 protein is labelled with His tag.

Sequence: MSFSGKYQLQ SQENFEAFMK AIGLPEELIQ KGKDIKGVSE IVQNGKHFKF TITAGSKVIQ NEFTVGEECE LETMTGEKVK TVVQLEGDNK LVTTFKNIKS VTELNGDIIT NTMTLGDIVF KRISKRI

Characteristics: FABP1, 1-127 aa, Human, His-tagged, Recombinant, E.coli

Purification: > 95% by SDS-PAGE

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0)

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Alternative Name: FABP1/L-FABP

Background: FABP1 (Fatty acid binding protein1) encodes the fatty acid binding protein found in liver. FABP1 is composed of ten antiparallel beta strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acid. This protein binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm, it may be involved in intracellular lipid transport and metabolism. Recombinant human FABP1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 16.3 kDa (147aa) confirmed by MALDI-TOF

NCBI Accession: NP_001434

Pathways: Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha