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ARL6 Protein (AA 1-186) (His tag)

Recombinant ARL6 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7676507
$779.62
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Quick Overview for ARL6 Protein (AA 1-186) (His tag) (ABIN7676507)

Target

See all ARL6 Proteins
ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Protein Type

Recombinant

Origin

  • 5
  • 1
  • 1
  • 1
Human

Source

  • 3
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 %
  • Protein Characteristics

    AA 1-186

    Purification tag / Conjugate

    This ARL6 protein is labelled with His tag.

    Sequence

    MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPT IGFSIEKFKS SSLSFTVFDM SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKH RRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ IQTVKT

    Characteristics

    ARL6, 1-186aa, Human, His tag, E.coli

    Purification

    > 90% by SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 0.2M NaCl,5 mM DTT

    Handling Advice

    Avoid repeated freezing and thawing cycles

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • Target

    ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

    Alternative Name

    BBS3/ARL6

    Background

    ARL6, also known ADP-ribosylation factor-like protein 6, belongs to the ARF family of GTP-binding proteins. This protein is known to play essential roles in modulating membrane trafficking and cytoskeletal functions. Mutation in ARL6 causes Bardet-Biedl syndrome (BBS3). BBS is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnor-malities and developmental delay. Recombinant human ARL6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

    Molecular Weight

    23.2 kDa (206aa) confirmed by MALDI-TOF

    NCBI Accession

    NP_115522
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