Matrix Gla Protein (MGP) (AA 20-96) peptide (His tag)

Catalog No. ABIN935117

Quick Overview for Matrix Gla Protein (MGP) (AA 20-96) peptide (His tag) (ABIN935117)

Target: MGP (Matrix Gla Protein (MGP))

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Product Details

Peptide Type: Recombinant

Protein Region: AA 20-96

Purification tag / Conjugate: This MGP peptide is labelled with His tag.

Sequence: MGSSHHHHHH SSGLVPRGSH MYESHESMES YELNPFINRR NANTFISPQQ RWRAKVQERI RERSKPVHEL NREACDDYRL CERYAMVYGYNAAYNRYF

Characteristics: Recombinant human MGP protein
Expression System: E.coli

Purity: > 90 % pure

Application Details

Application Notes: MGP protein has been used in SDS PAGE, and may be suitable for use in other assays

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. 20 mM Tris-HCl buffer (pH8.0) containing 10 % glycerol.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.

Target Details

Target: MGP (Matrix Gla Protein (MGP))

Background: MGP, also known as Matrix Gla protein, is a protein involved in regulating calcification in the extracellular matrix, in particular in cartilage and arteries. MGP is a vitamin K-dependent protein, and contains five to six residues of Gla, a Ca2+ binding AA requiring vitamin K-dependent gamma carboxylase for its formation. It is found in human bone extracts, likely formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity. Recombinant human MGP protein, fused to His-tag at N-terminus, was expressed in E. coli and denatured using detergent during a conventional chromatography purification process.
Alternative Names: GIG36 protein, NTI protein, MGLAP protein, Matrix Gla protein isoform 2 precursor protein

Molecular Weight: 11.8 kDa (98 AA)