IL-19 Protein
Quick Overview for IL-19 Protein (ABIN935484)
Target
See all IL-19 (IL19) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA
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Characteristics
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Purified recombinant Human IL19 protein
Expression System: E.coli
Bioactivity: Determined by its ability to activate STAT following receptor-ligand interaction. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 19 (IL19) (AA 1-215) protein (GST tag)
IL19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 19 (IL19) (Active) proteinIL19 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 19 (IL19) (AA 25-177) protein (Fc Tag)IL19 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 19 (IL19) (AA 25-176) protein (His tag)IL19 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 10 mM sodium citrate pH 3.0 to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 10 mM sodium citrate, pH 5.0.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IL-19 (IL19) (Interleukin 19 (IL19))
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Alternative Name
- IL19
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Background
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IL19 belongs to the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL19 is a proinflammatory cytokine because it up-regulates IL6 and TNF-alpha and induces apoptosis through TNF-alpha. IL19 signals through the type I IL20R. Human and Mouse IL19 share 71 % amino acid sequence identity.
Alternative Names: IL-19, Melanoma differentiation association like protein protein, IL-19 protein, IL-19 protein, IL 19 protein, IL 19, IL19, Interleukin 19 protein -
Molecular Weight
- 17.9 kDa
Target
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