CCL4 Protein
Quick Overview for CCL4 Protein (ABIN935659)
Target
See all CCL4 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- APIGSDPPTS CCFSYTSRKI HRNFVMDYYE TSSLCSQPAV VFLTKKGRQI CADPSEPWVN EYVNDLELN
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Characteristics
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Purified recombinant Human MIP1 beta protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.01-1.0 µg/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein
CCL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant CMA Active
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein (Biotin)CCL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein (His tag)CCL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (His-IF2DI Tag)CCL4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (His-IF2DI Tag)CCL4 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
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Alternative Name
- MIP1 beta
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Background
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Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells.
Alternative Names: Macrophage Inflammatory Protein-1beta protein, CCL4 protein, MIP beta 1 protein, MIP-1 beta protein, ACT-2 protein, MIP1 beta, MIP beta-1, MIP beta 1, MIP beta-1 protein -
Molecular Weight
- 7.8 kDa
Target
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