CCL22 Protein

Catalog No. ABIN935664

This Recombinant CCL22 protein is expressed in Escherichia coli (E. coli).

Quick Overview for CCL22 Protein (ABIN935664)

Target: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS

Characteristics: Purified recombinant Mouse MDC protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human activated lymphoytes using a concentration of 10.0-100.0 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Alternative Name: MDC

Background: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity.
Alternative Names: STCP-1 protein, CCL22 protein, Macrophage-Derived Chemokine protein, ABCD-1 protein

Molecular Weight: 7.8 kDa