TACI Protein
Quick Overview for TACI Protein (ABIN935869)
Target
See all TACI (TNFRSF13B) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL PGLKLSADQV
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Characteristics
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Purified recombinant Human TACI protein
Expression System: E.coli
Bioactivity: Determined by its ability to bl °Ck human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 µg/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (AA 2-165) protein (His-DYKDDDDK-Strep II Tag)
TNFRSF13B Origin: Human Host: HEK-293T Cells Recombinant SDS, ELISA, WB, PI
Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (AA 2-165) protein (Fc Tag)TNFRSF13B Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (AA 2-166) protein (Fc Tag,AVI tag,Biotin)TNFRSF13B Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (AA 1-125) protein (Fc Tag)TNFRSF13B Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (AA 1-160) protein (His tag)TNFRSF13B Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (AA 1-165) protein (hIgG-His-tag)TNFRSF13B Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
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Alternative Name
- TACI
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Background
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TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI binds to both APRIL and BAFF and can stimulate the activation of transcription factors, NF-kappaB, AP-1, and mediates calcineurin dependent activation of NF-AT (nuclear-factor of activated T cells). TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRILstimulated proliferation of primary B-cells by blocking the binding of APRIL to the membrane anchored TACI receptor.
Alternative Names: TNFRSF13B protein, Transmembrane activator and CAML interactor protein -
Molecular Weight
- 17.8 kDa
Target
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