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YARS2 antibody (C-Term)

YARS2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB14936 unconjugated
Catalog No. ABIN1882153
  • Target See all YARS2 Antibodies
    YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 399-427, C-Term
    Reactivity
    • 22
    • 11
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YARS2 antibody is un-conjugated
    Application
    • 14
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This YARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the C-terminal region of human YARS2.
    Clone
    RB14936
    Isotype
    Ig Fraction
    Top Product
    Discover our top product YARS2 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Riley, Menezes, Rudinger-Thirion, Duff, de Lonlay, Rotig, Tchan, Davis, Cooper, Christodoulou: "Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia." in: Orphanet journal of rare diseases, Vol. 8, pp. 193, (2014) (PubMed).

    Riley, Cooper, Hickey, Rudinger-Thirion, McKenzie, Compton, Lim, Thorburn, Ryan, Giegé, Bahlo, Christodoulou: "Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome." in: American journal of human genetics, Vol. 87, Issue 1, pp. 52-9, (2010) (PubMed).

    Bonnefond, Frugier, Touzé, Lorber, Florentz, Giegé, Sauter, Rudinger-Thirion: "Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features." in: Structure (London, England : 1993), Vol. 15, Issue 11, pp. 1505-16, (2007) (PubMed).

  • Target
    YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))
    Alternative Name
    YARS2 (YARS2 Products)
    Synonyms
    2210023C10Rik antibody, tyrRS antibody, CGI-04 antibody, RGD1311696 antibody, MLASA2 antibody, MT-TYRRS antibody, TYRRS antibody, tyrosyl-tRNA synthetase 2 (mitochondrial) antibody, tyrosyl-tRNA synthetase 2 antibody, Yars2 antibody, YARS2 antibody
    Background
    YARS2 catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
    Molecular Weight
    53199
    NCBI Accession
    NP_001035526
    UniProt
    Q9Y2Z4
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