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PRDM6 Proteins

(PR Domain Containing 6 (PRDM6))

Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).

recommended

PRDM6 Protein (AA 1-595) (Strep Tag) (ABIN3094724)

Crystallography grade PRDM6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

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recommended

PRDM6 Protein (AA 1-596) (Strep Tag) (ABIN3135115)

Crystallography grade PRDM6 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

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PRDM6 Proteins by Grade

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PRDM6 Proteins by Origin

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PRDM6 Proteins by Source

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PRDM6 Proteins by Protein Type

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PRDM6 Proteins by Application

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Popular PRDM6 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PRDM6 Protein (AA 1-595) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3094724

Quantity 1 mg

Datasheet Datasheet

PRDM6 Protein (AA 1-596) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3135115

Quantity 1 mg

Datasheet Datasheet

Aliases for PRDM6 Proteins

PR/SET domain 6 (PRDM6) Proteins
PR domain containing 6 (Prdm6) Proteins
PR/SET domain 6 (Prdm6) Proteins
putative histone-lysine N-methyltransferase PRDM6 (LOC100354345) Proteins
PR domain containing 6 (prdm6) Proteins
Gm92 Proteins
PRDM6 Proteins
PRISM Proteins
RGD1559594 Proteins

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PRDM6 Proteins by Grade

PRDM6 Proteins by Origin

PRDM6 Proteins by Source

PRDM6 Proteins by Protein Type

PRDM6 Proteins by Application

Popular PRDM6 Proteins

Aliases for PRDM6 Proteins

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