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Browse our anti-IGF1 (IGF1) Antibodies

Full name:
anti-Insulin-Like Growth Factor 1 Antibodies (IGF1)
On are 413 Insulin-Like Growth Factor 1 (IGF1) Antibodies from 32 different suppliers available. Additionally we are shipping IGF1 Kits (179) and IGF1 Proteins (157) and many more products for this protein. A total of 762 IGF1 products are currently listed.
C730016P09Rik, Igf-1, IGF-1a, IGF-1L, Igf-I, IGF-IB, IGF1, IGF1A, IGFI, IGFIA, Npt2B

All available anti-IGF1 Antibodies

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Top referenced anti-IGF1 Antibodies

  1. Human Polyclonal IGF1 Primary Antibody for IF (p), IHC (p) - ABIN723605 : Baykara, Aksu, Buyuk, Kiray, Sisman, Baykara, Dayi, Tas, Ozdemir, Arda, Uysal et al.: Progesterone treatment decreases traumatic brain injury induced anxiety and is correlated with increased serum IGF-1 levels; prefrontal cortex, amygdala, hippocampus neuron density; and reduced serum ... in Biotechnic & histochemistry : official publication of the Biological Stain Commission 2013 (PubMed)
    Show all 4 references for ABIN723605

  2. Human Polyclonal IGF1 Primary Antibody for FACS, IF - ABIN658020 : Li, Yin, Hua, Sun, Luo, Wang, Jiang: The reciprocal regulation of gamma-synuclein and IGF-I receptor expression creates a circuit that modulates IGF-I signaling. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for ABIN658020

  3. Mouse (Murine) Polyclonal IGF1 Primary Antibody for WB - ABIN4321494 : Go, Srivastava, Hernandez-Ono, Gang, Smith, Booth, Ginsberg, Mani: The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue. in Cell metabolism 2014 (PubMed)

  4. Human Polyclonal IGF1 Primary Antibody for ELISA, WB - ABIN4321495 : Furundzija, Fritzsche, Kaufmann, Meyborg, Fleck, Kappert, Stawowy: IGF-1 increases macrophage motility via PKC/p38-dependent alphavbeta3-integrin inside-out signaling. in Biochemical and biophysical research communications 2010 (PubMed)

  5. Human Polyclonal IGF1 Primary Antibody for ICC, IF - ABIN4321496 : Lin, Jan, Kuo: Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. in Molecular pharmaceutics 2015 (PubMed)

  6. Human Polyclonal IGF1 Primary Antibody for Neut, ELISA - ABIN223533 : Lewy, Ryan, Read, Fong, Poole, Seed, Sharma, Smith, Kwan, Stewart, Bacon, Warfield, Franklyn, McCabe, Boelaert: Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells. in Endocrinology 2013 (PubMed)

  7. Mouse (Murine) Polyclonal IGF1 Primary Antibody for IP, IHC - ABIN1586056 : Malempati, Weigel, Ingle, Ahern, Carroll, Roberts, Reid, Schmechel, Voss, Cho, Chen, Krailo, Adamson, Blaney: Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: a report from the Children's Oncology Group. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 (PubMed)

  8. Human Monoclonal IGF1 Primary Antibody for EIA, IHC (fro) - ABIN111026 : Morrell, Dadi, More, Taylor, Dabestani, Buchanan, Holder, Preece: A monoclonal antibody to human insulin-like growth factor-I: characterization, use in radioimmunoassay and effect on the biological activities of the growth factor. in Journal of molecular endocrinology 1989 (PubMed)

More Antibodies against IGF1 Interaction Partners

Zebrafish Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. Study demonstrated that IGF-I can stimulate egfr (show EGFR Antibodies) expression in both follicles cell culture and intact follicles promoting oocyte maturation.

  2. IGF-I-induced kitlga expression is inhibited by epidermal growth factor (show EGF Antibodies), an oocyte-derived paracrine factor in the zebrafish follicle.

  3. hypoxia causes PGC (show PGC Antibodies) migration defect by inhibiting IGF signaling through the induction of IGFBP-1 (show IGFBPI Antibodies)

  4. Whereas hypoxia repressed the Igf1 receptor and its downstream Erk1/2 (show MAPK1/3 Antibodies) and Akt (show AKT1 Antibodies) signaling activities, re-oxygenation restored their activities

  5. IGF signalling influences expression of BMP2b (show BMP4 Antibodies), a gene that plays an important role in zebrafish pattern formation

  6. The insulin-like growth factor 1 gene can be differentially transcribed to yield two distinct IGF-1 mRNA transcripts

  7. zebrafish XBP-1 (show XBP1 Antibodies) spliced form not only activates genes responsible for protein folding, transporting, glycosylation and Endoplasmic Reticulum associated degradation but also activates anti-apoptosis signal via IGF1/Akt (show AKT1 Antibodies) pathway in unfolded protein

Mouse (Murine) Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. vascular smooth muscle-derived IGF-1 plays a critical role in hypoxia-induced pulmonary hypertension.

  2. Overexpression of IGF-I in the osteoblast lineage does not contribute to an increase in repair of erosions or syndesmophyte formation in mouse models for destructive and remodeling arthritis.

  3. Under nonpathological conditions, IGF-1 regulates brain IGF-IR

  4. These findings highlight the sex-dependent and potentially detrimental effects of in utero smoke exposure on DNA methylation (show HELLS Antibodies) and Igf1 and Igf1r (show IGF1R Antibodies) mRNA levels.

  5. Liver-derived IGF-I regulates cortical bone mass, cortical porosity, and mechanical strength under normal (nonloaded) conditions. However, despite an approximately 70% reduction in circulating IGF-I, the osteogenic response to mechanical loading was not attenuated in the LI-IGF-I(-/-) mice.

  6. The effects were abolished by using pharmacological inhibition of PI3K/Akt (show AKT1 Antibodies) with LY294002 and paralleled by transfecting DCs with klotho (show KL Antibodies) siRNA. In conclusion, the regulation of klotho (show KL Antibodies) sensitive DC function by IGF-1 or insulin (show INS Antibodies) is mediated through PI3K/Akt (show AKT1 Antibodies) signaling pathway in BMDCs.

  7. These results show that IGF1 signaling shapes the macrophage-activation phenotype.

  8. Serum IGF-1 level of HFD TRAMP (show DPT Antibodies) mice was significantly higher than that of normal diet TRAMP (show DPT Antibodies) mice, increasing with age. The IGF-1 related pathway played an important role in high-fat diet promotion of TRAMP (show DPT Antibodies) mouse PCa (show ENPP1 Antibodies) development and progression.

  9. Upregulation of miR26b in mouse cells downregulated the insulinlike growth factor 1 (IGF1) protein expression level and promoted beta-amyloid production.

  10. These results indicate that there is a tissue-specific regulation of IGF-1/PI3K/Akt (show AKT1 Antibodies) during normal aging and upon dietary restriction to help maintain the metabolic status of these tissues at those phases of animal's lifespan.

Guinea Pig Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. Local IGF-1 might play a role in the lesion- and deafness-induced plasticity in FC and at AN/FC synapse following chronic kanamycin-induced deafness.

Human Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. Plasma IGF1 was elevated in patients with systemic sclerosis.

  2. physiological levels of GH rapidly stimulate human IGF1 gene transcription and identify several potential transcriptional enhancers in chromatin that bind STAT5b (show STAT5B Antibodies) in a GH-regulated way. Each of the putative enhancers also activates a human IGF1 gene promoter in reconstitution experiments in the presence of the GH receptor (show GHR Antibodies), STAT5b (show STAT5B Antibodies), and GH.

  3. The total number of different alleles detected per gene in the population varied over an approximately 15-fold range, from 57 for IGF1 to 872 for IGF2R (show IGF2R Antibodies), although when corrected for protein length the rate ranged from 0.22 to 0.59 changes/codon among the 11 genes evaluated.

  4. Growth velocity in infants is influenced by associations between levels of testosterone, estradiol, and IGF1.

  5. We concluded that USP15 (show USP15 Antibodies) attenuates IGF-I signaling by antagonizing Nedd4 (show NEDD4 Antibodies)-induced IRS-2 (show IRS2 Antibodies) ubiquitination.

  6. this study identified several loci associated with circulating IGF-I and IGFBP-3 (show IGFBP3 Antibodies) concentrations and provides clues to the potential role of the IGF axis in mediating effects of known (FOXO3 (show FOXO3 Antibodies)) and novel (ASXL2 (show ASXL2 Antibodies)) longevity-associated loci.

  7. these findings suggest that IGFBP-3 (show IGFBP3 Antibodies) suppresses transcription of EGR1 (show EGR1 Antibodies) and its target genes bFGF (show FGF2 Antibodies) and PDGF (show PDGFA Antibodies) through inhibiting IGF-1-dependent ERK (show EPHB2 Antibodies) and AKT (show AKT1 Antibodies) activation.

  8. No association between physical activity or fitness in adolescence and cognitive function in adulthood was found in females, nor any intermediate role for IGF-I in either sex.

  9. Short-term treatment with progressive doses of rhIGF1 (recombinant human insulin-like growth factor-1) improved growth in two siblings with deficiency of PAPP-A2 (pregnancy-associated plasma protein-A2 (show PAPPA2 Antibodies)) [due to a homozygous loss-of-function frameshift mutation in exon 3 of the PAPP-A2 (show PAPPA2 Antibodies) gene (p.D643fs25*)] that resulted in postnatal growth failure due to resulting decrease in IGF1 bioavailability. [CASE REPORT]

  10. This is the first study demonstrating Treg-enhancing effects of IGF-1. Thus IGF-1 can be accounted for modulating Treg cell-related action in Graves' Orbitopathy

Cow (Bovine) Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. It has been shown that several specific genes which are differentially regulated, including IGF-1, might impact dairy fertility.

  2. There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 (show STAT5A Antibodies) ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.

  3. Associations between genetic variants in the promoter region of the insulin-like growth factor-1 (IGF1) gene and blood serum IGF1 concentration in Hanwoo cattle.

  4. The association of IGF1, GH, and PIT1 (show POU1F1 Antibodies) markers with growth and reproductive traits were assessed.

  5. These findings strongly support the concept that IGF-1 upregulates LHR (show LHCGR Antibodies) expression in granulosa cells and that IGF-1 is required for determining which follicle becomes dominant and acquires ovulatory capacity.

  6. Insulin (show INS Antibodies)-induced glucose uptake in lactating bovine mammary epithelial cells may involve the phosphatidylinositide 3-kinase- but not mitogen-activated protein kinase (show MAPK1 Antibodies)-mediated signaling pathways.

  7. Data show that individuals with insulin-like growth factor I (IGF-1) allele C had a significantly higher performance in production traits.

  8. Uterine concentrations of IGFBPs are cycle stage specific and also suggests IGF1-dependent and -independent functions for IGFBPs during a time of major change in the developing embryo.

  9. This study evaluated the relationship of IGF-I levels to several other determinants of feed intake in Red Angus cross cattle.

  10. Production and reproduction traits in Holstein cattle associated with single nucleotide polymorphisms in the IGF1 gene.

Pig (Porcine) Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. This study demonstrated that Up-regulation of IGF-1 in the frontal cortex of piglets exposed to an environmentally enriched arena.

  2. Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF (show HGF Antibodies) enhances neovascularization but moderately improves cardiac regeneration in a porcine model.

  3. Results show that expression changes of IGF1 genes were associated with C/EBP (show CEBPA Antibodies) b expression during embryonic and postnatal development in porcine liver.

  4. genetic association study suggests that the TC genotype of IGF-1 represents the selection genotype for smaller in size.

  5. IGF-I coordinately regulates multiple cell signaling pathways that are critical to proliferation, migration and survival of trophectoderm cells during early pregnancy in pigs.

  6. IGF-1 splice variant (mechano growth factor) is expressed within the growth plate, but the addition of its peptides was not associated with growth plate chondrocytes proliferation.

  7. alpha-linolenic acid increased IGF-I secretion from hepatocytes.

  8. Copper can stimulate chondrocyte proliferation by promoting the expression of IGF-1.

  9. The results show that modulation of plasma insulin (show INS Antibodies) levels by dietary carbohydrates seems possible in anabolic sows, but IGF-I levels are less easily modified.

  10. The results suggested that IFG (show IFNG Antibodies)-1 and -2 and their receptors are differentially expressed at the maternal and fetal components of the attachment site.

Rabbit Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction.

  2. Our studies demonstrate that the active SVCT2 (show SLC23A2 Antibodies) is expressed in IVD (show IVD Antibodies) cells and that the expression of this transporter is regulated by growth factors IGF-1 and dexamethasone.

  3. increased endogenous IGF1 and IGF2 expression by the blastocyst compensates for the loss of systemic insulin (show INS Antibodies) and IGF.

  4. IGF1 showed a significantly higher capacity to form the posterior mesoderm and primitive streak (stage 2 and 3) than blastocysts cultured without growth factors

  5. Overall, IGF-1 promoted atherosclerosis by affecting endothelial function and aging.

Horse (Equine) Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. Data suggest that metabolism of IGF1, IGF2, and IGFBP3 (insulin-like growth factor binding protein-3 (show IGFBP3 Antibodies)) can be altered by dietary modifications (here, long-term caloric restriction in Welsh Pony mares).

  2. The laminar cell types expressing insulin receptor (show INSR Antibodies) and/or insulin-like growth factor-1 receptor (show IGF1R Antibodies) and the effect of dietary carbohydrates on their expression are reported.

  3. Increased expression of IGF-1 in female equine embryos. Sex-related influences on expression of the IGF system are probably related to a gradual X chromosome inactivation.

  4. Somatomedin (IGF-I) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor (show IGF1R Antibodies) is present in spermatogonia, spermatocytes and Leydig cells.

  5. Hsp90 (show HSP90AB1 Antibodies) inhibitor geldanamycin is used to assess age-related responses with IGF1 stimulation of chondrocytes.

Goat Insulin-Like Growth Factor 1 (IGF1) interaction partners

  1. These results suggest the significant influence of the IGF1 gene on prolificacy in goats and identified SNPs would benefit the selection of prolific animals in future breeding programs.

IGF1 Antigen Profile

Antigen Summary

The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IGF1

  • insulin-like growth factor 1 (igf1) antibody
  • insulin-like growth factor 1 (Igf1) antibody
  • insulin-like growth factor 1 (somatomedin C) (IGF1) antibody
  • prepro IGF-I (IGF-I) antibody
  • C730016P09Rik antibody
  • Igf-1 antibody
  • IGF-1a antibody
  • IGF-1L antibody
  • Igf-I antibody
  • IGF-IB antibody
  • IGF1 antibody
  • IGF1A antibody
  • IGFI antibody
  • IGFIA antibody
  • Npt2B antibody

Protein level used designations for IGF1

igf1a , insulin-like growth factor I , somatomedin , IGF-I , IGF-IA , IGF-IB , MGF , insulin-like growth factor 1 , insulin-like growth factor IA , insulin-like growth factor IB , mechano growth factor , somatomedin-C , class 1 insulin-like growth factor I preproprotein , insulin growth factor-1 , insulin like growth factor 1 , insulin-like growth factor I (somatomedin C) , insulin-like growth factor I variant 1 , insulin-like growth factor-1 , prepro-IGF-I , Insulin-like growth factor I , somatomedin C , Somatomedin , insulin like growth factor-1 , insulin-like growth factor-I

114433 Danio rerio
16000 Mus musculus
24482 Rattus norvegicus
100135551 Cavia porcellus
3479 Homo sapiens
281239 Bos taurus
610255 Canis lupus familiaris
397491 Sus scrofa
100008668 Oryctolagus cuniculus
100034198 Equus caballus
443318 Ovis aries
418090 Gallus gallus
100860838 Capra hircus
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