Browse our PDGFB (PDGFB) ELISA Kits

Full name:
Platelet-Derived Growth Factor beta Polypeptide ELISA Kits (PDGFB)
On www.antibodies-online.com are 62 Platelet-Derived Growth Factor beta Polypeptide (PDGFB) ELISA Kits from 11 different suppliers available. Additionally we are shipping PDGFB Antibodies (87) and PDGFB Proteins (42) and many more products for this protein. A total of 198 PDGFB products are currently listed.
Synonyms:
c-sis, PDGF-2, PDGF-B, PDGF2, SIS, SSV
list all ELISA KIts Gene Name GeneID UniProt
PDGFB 18591 P31240
PDGFB 5155 P01127
PDGFB 24628 Q05028

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More ELISA Kits for PDGFB Interaction Partners

Mouse (Murine) Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. PDGF-B-PDGFRbeta signaling plays a significant role in the development of adipose tissue neovascularization.

  2. data suggest that the stronger fibrotic effect generated by Pdgfa (show PDGFA ELISA Kits) overexpression was mediated by Pdgfralpha in cardiac interstitial mesenchymal cells

  3. loss-of-function mutations in PDGFB or PDGFRB (show PDGFRB ELISA Kits) cause Primary Familial Brain Calcification.

  4. Results suggest that regional Pax3 (show PAX3 ELISA Kits) expression not only marks a novel subset of High-grade Brainstem Glioma but also contributes to PDGF-B-induced brainstem gliomagenesis

  5. High PDGFB expression is associated with liver fibrosis.

  6. Increased expression of STAT5b (show STAT5B ELISA Kits) + PDGFB led to increased expression of downstream STAT5b (show STAT5B ELISA Kits) targets.

  7. Platelets produce PDGFB to activate stellate cells and promote fibrosis in MDR2 (show ABCB4 ELISA Kits)-null mice.

  8. The endogenous levels of PDGF (show PDGFA ELISA Kits)-BB, increases CD31 (show PECAM1 ELISA Kits)(hi)endomucin (show EMCN ELISA Kits)(hi) vessel number and stimulates bone formation in ovariectomy mice.

  9. These findings thus implicate a novel role of PDGF (show PDGFA ELISA Kits)-BB in the migration of pericytes, resulting in loss of pericyte coverage from the endothelium with a subsequent breach of the blood-brain barrier

  10. The data indicate a dual role of Lhx2 (show LHX2 ELISA Kits) during EMT (show ITK ELISA Kits) and tumor progression: by inducing the expression of PDGF-B, Lhx2 (show LHX2 ELISA Kits) provokes an autocrine PDGF-B/PDGFRbeta loop required for cell migration, invasion and metastatic dissemination

Human Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. Insulin (show INS ELISA Kits) treatment caused sustained Akt (show AKT1 ELISA Kits) activity, whereas EGF (show EGF ELISA Kits) or PDGF (show PDGFA ELISA Kits)-AA promoted transient signaling; PDGF (show PDGFA ELISA Kits)-BB produced sustained responses at higher concentrations.Transient responses to EGF (show EGF ELISA Kits) were caused by negative feedback at the receptor level, as a second treatment yielded minimal responses, whereas parallel exposure to IGF-I (show IGF1 ELISA Kits) caused full Akt (show AKT1 ELISA Kits) activation

  2. high-throughput affinity plasma proteomic profiling is a valuable research strategy to identify potential candidate biomarkers for thrombosis-related disorders, and our study suggests a novel association of PDGFB plasma levels with venous thromboembolism.

  3. High PDGFB expression is associated with glioma.

  4. A cell-autonomous positive-signaling circuit is associated with the PDGF (show PDGFA ELISA Kits)-NO-ID4 (show ID4 ELISA Kits)-regulatory axis in glioblastoma cells.

  5. SphK1 (show SPHK1 ELISA Kits) is regulated by PDGF (show PDGFA ELISA Kits)-BB in pulmonary artery smooth muscle cells via the transcription factor Egr-1 (show EGR1 ELISA Kits), promoting cell proliferation.

  6. PDGF (show PDGFA ELISA Kits)-BB regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner.

  7. Low concentration of PDGF (show PDGFA ELISA Kits)-AB showed synergism with IFN-alpha (show IFNA ELISA Kits) in IFN-beta (show IFNB1 ELISA Kits) and -gamma induction.

  8. There are four platelet-derived growth factor (PDGF (show PDGFA ELISA Kits)) genes (PDGFA (show PDGFA ELISA Kits), PDGFB, PDGFC (show PDGFC ELISA Kits) and PDGFD (show PDGFD ELISA Kits)) that reside on chromosomes 7, 22, 4 and 11.

  9. this study shows that the expression of PDGFB is significantly downregulated in keloid fibroblasts compared to normal human fibroblasts

  10. this study demonstrated that knockdown of SCARA5 (show SCARA5 ELISA Kits) inhibits PDGFBBinduced HASMC proliferation and migration through suppression of the PDGF (show PDGFA ELISA Kits) signaling pathway.

Cow (Bovine) Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. Study suggest that PDGF-B is induced by hypoxia and protects against apoptosis via the PI3K/Akt (show AKT1 ELISA Kits)/Stat3 (show STAT3 ELISA Kits) signaling pathway.

  2. PDGF-B transcription is increased by Nuclear Factor Kappa B

  3. up-regulated by Angiotensin II in retinal pericytes; results suggest that Ang II (show AGT ELISA Kits)-type 1 receptor interaction could stimulate PDGF-B gene expression in cultured retinal pericytes through intracellular reactive oxygen species generation

  4. PEDF promotes growth of pericytes through autocrine production of PDGFB.

  5. Hypoxia enhances PDGF-B paracrine interactions between glomerular endothelial and mesangial cells.

PDGFB Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with PDGFB

  • platelet-derived growth factor beta polypeptide (PDGFB) Elisa Kit
  • platelet derived growth factor, B polypeptide (Pdgfb) Elisa Kit
  • platelet-derived growth factor beta polypeptide (Pdgfb) Elisa Kit
  • c-sis Elisa Kit
  • PDGF-2 Elisa Kit
  • PDGF-B Elisa Kit
  • PDGF2 Elisa Kit
  • SIS Elisa Kit
  • SSV Elisa Kit

Protein level used designations for PDGFB

platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) , PDGF subunit B , PDGF-2 , c-sis , platelet-derived growth factor B chain , platelet-derived growth factor beta polypeptide , platelet-derived growth factor subunit B , proto-oncogene c-Sis , PDGF, B chain , becaplermin , platelet-derived growth factor 2 , platelet-derived growth factor, beta polypeptide (oncogene SIS) , Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis) , pdgf protein , platelet derived growth factor, B polypeptide , platelet-derived growth factor B , v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog) , platelet-derived growth factor B subunit

GENE ID SPECIES
100228287 Taeniopygia guttata
18591 Mus musculus
5155 Homo sapiens
24628 Rattus norvegicus
100126843 Sus scrofa
442986 Canis lupus familiaris
540106 Bos taurus
100731469 Cavia porcellus
374128 Gallus gallus
443545 Ovis aries
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