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Rat (Rattus) PDGFB ELISA Kit for Sandwich ELISA - ABIN431524
Salva, Turan, Akbuğa: Inhibition of Glomerular Mesangial Cell Proliferation by siPDGF-B- and siPDGFR-β-Containing Chitosan Nanoplexes. in AAPS PharmSciTech 2016
High PDGFB expression is associated with gastric cancer.
We observed that regenerating and necrotic muscle fibers in muscle biopsy samples from Duchenne muscular dystrophy (show DMD ELISA Kits) patients expressed PDGF (show PDGFA ELISA Kits)-BB.
Elevated PDGFB expression was noted in 29% of patients with papillary renal cell carcinoma.
Insulin (show INS ELISA Kits) treatment caused sustained Akt (show AKT1 ELISA Kits) activity, whereas EGF (show EGF ELISA Kits) or PDGF (show PDGFA ELISA Kits)-AA promoted transient signaling; PDGF (show PDGFA ELISA Kits)-BB produced sustained responses at higher concentrations.Transient responses to EGF (show EGF ELISA Kits) were caused by negative feedback at the receptor level, as a second treatment yielded minimal responses, whereas parallel exposure to IGF-I (show IGF1 ELISA Kits) caused full Akt (show AKT1 ELISA Kits) activation
high-throughput affinity plasma proteomic profiling is a valuable research strategy to identify potential candidate biomarkers for thrombosis-related disorders, and our study suggests a novel association of PDGFB plasma levels with venous thromboembolism.
High PDGFB expression is associated with glioma.
A cell-autonomous positive-signaling circuit is associated with the PDGF (show PDGFA ELISA Kits)-NO-ID4 (show ID4 ELISA Kits)-regulatory axis in glioblastoma cells.
SphK1 (show SPHK1 ELISA Kits) is regulated by PDGF (show PDGFA ELISA Kits)-BB in pulmonary artery smooth muscle cells via the transcription factor Egr-1 (show EGR1 ELISA Kits), promoting cell proliferation.
PDGF (show PDGFA ELISA Kits)-BB regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner.
Low concentration of PDGF (show PDGFA ELISA Kits)-AB showed synergism with IFN-alpha (show IFNA ELISA Kits) in IFN-beta (show IFNB1 ELISA Kits) and -gamma induction.
intrinsic PDGF-B expressed in the spinal cord may play an essential role in neuroregulation in primates following cord hemisection
Study suggest that PDGF-B is induced by hypoxia and protects against apoptosis via the PI3K/Akt (show AKT1 ELISA Kits)/Stat3 (show STAT3 ELISA Kits) signaling pathway.
PDGF-B transcription is increased by Nuclear Factor Kappa B
up-regulated by Angiotensin II in retinal pericytes; results suggest that Ang II (show AGT ELISA Kits)-type 1 receptor interaction could stimulate PDGF-B gene expression in cultured retinal pericytes through intracellular reactive oxygen species generation
PEDF promotes growth of pericytes through autocrine production of PDGFB.
Hypoxia enhances PDGF-B paracrine interactions between glomerular endothelial and mesangial cells.
These results demonstrate the requirement of lymphatic endothelial cells-autonomous PDGFB expression and retention for smooth muscle cell recruitment to lymphatic vessels.
Mechanical strain stimulates vasculogenesis of embryonic stem cells by the intracellular messengers ROS (show ROS1 ELISA Kits), NO and calcium as well as by upregulation of angiogenesis guidance molecules and the angiogenic growth factors VEGF (show VEGFA ELISA Kits), FGF-2 (show FGF2 ELISA Kits) and PDGF (show PDGFA ELISA Kits)-BB.
PDGF-B-PDGFRbeta signaling plays a significant role in the development of adipose tissue neovascularization.
data suggest that the stronger fibrotic effect generated by Pdgfa (show PDGFA ELISA Kits) overexpression was mediated by Pdgfralpha in cardiac interstitial mesenchymal cells
loss-of-function mutations in PDGFB or PDGFRB (show PDGFRB ELISA Kits) cause Primary Familial Brain Calcification.
Results suggest that regional Pax3 (show PAX3 ELISA Kits) expression not only marks a novel subset of High-grade Brainstem Glioma but also contributes to PDGF-B-induced brainstem gliomagenesis
High PDGFB expression is associated with liver fibrosis.
Increased expression of STAT5b (show STAT5B ELISA Kits) + PDGFB led to increased expression of downstream STAT5b (show STAT5B ELISA Kits) targets.
Platelets produce PDGFB to activate stellate cells and promote fibrosis in MDR2 (show ABCB4 ELISA Kits)-null mice.
The endogenous levels of PDGF (show PDGFA ELISA Kits)-BB, increases CD31 (show PECAM1 ELISA Kits)(hi)endomucin (show EMCN ELISA Kits)(hi) vessel number and stimulates bone formation in ovariectomy mice.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
PDGF subunit B
, PDGF, B chain
, platelet-derived growth factor 2
, platelet-derived growth factor B chain
, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
, platelet-derived growth factor subunit B
, platelet-derived growth factor, beta polypeptide (oncogene SIS)
, proto-oncogene c-Sis
, platelet-derived growth factor B
, v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)
, platelet-derived growth factor beta polypeptide
, Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis)
, pdgf protein
, platelet derived growth factor, B polypeptide
, platelet-derived growth factor B subunit