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Browse our anti-COMT (COMT) Antibodies

Full name:
anti-Catechol-O-Methyltransferase Antibodies (COMT)
On www.antibodies-online.com are 187 Catechol-O-Methyltransferase (COMT) Antibodies from 24 different suppliers available. Additionally we are shipping COMT Kits (33) and COMT Proteins (29) and many more products for this protein. A total of 261 COMT products are currently listed.
Synonyms:
comt, Comt1, D16Wsu103e, D330014B15Rik, mb-comt, MGC154444, s-comt

Most Popular Reactivities for anti-COMT (COMT) Antibodies

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anti-Human COMT Antibodies:

anti-Mouse (Murine) COMT Antibodies:

anti-Rat (Rattus) COMT Antibodies:

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Top referenced anti-COMT Antibodies

  1. Human Polyclonal COMT Primary Antibody for ELISA, WB - ABIN185328 : Tunbridge, Harrison, Weinberger: Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond. in Biological psychiatry 2006 (PubMed)
    Show all 5 references for ABIN185328

  2. Human Monoclonal COMT Primary Antibody for WB - ABIN393532 : Bodenmann, Landolt: Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT. in Sleep 2010 (PubMed)
    Show all 5 references for ABIN393532

  3. Human Monoclonal COMT Primary Antibody for WB - ABIN1882224 : Zeng, Ye, Lu, Chua, Tan, Zhong: Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes. in Organic letters 2010 (PubMed)
    Show all 5 references for ABIN1882224

  4. Mouse (Murine) Monoclonal COMT Primary Antibody for BI, IF - ABIN968704 : Gogos, Morgan, Luine, Santha, Ogawa, Pfaff, Karayiorgou: Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 3 references for ABIN968704

  5. Human Polyclonal COMT Primary Antibody for WB - ABIN514522 : Hevir, Sinkovec, Rižner: Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT. in Molecular and cellular endocrinology 2010 (PubMed)

  6. Human Polyclonal COMT Primary Antibody for WB - ABIN2781821 : Shiels, Huang, Hoffman, Shugart, Bolton, Platz, Helzlsouer, Alberg: A community-based study of cigarette smoking behavior in relation to variation in three genes involved in dopamine metabolism: Catechol-O-methyltransferase (COMT), dopamine beta-hydroxylase (DBH) and monoamine oxidase-A (MAO-A). in Preventive medicine 2008 (PubMed)

More Antibodies against COMT Interaction Partners

Horse (Equine) Catechol-O-Methyltransferase (COMT) interaction partners

  1. An analysis of polymorphisms of the COMT gene as a preliminary step in evaluating the role of the gene in behavior is reported.

Human Catechol-O-Methyltransferase (COMT) interaction partners

  1. This study demonstrated that Catechol-O-methyltransferase val/met polymorphism with cognitive function in Gilles de la Tourette syndrome patients.

  2. Women with COMT Val/Val genotype are at high risk of developing multiple uterine fibroids either positive or negative for MED12 (show MED12 Antibodies) exon 2 mutations.

  3. we genotyped five hormone-related genes: estrogen receptor-alpha (ESR1 (show ESR1 Antibodies)), aromatase (CYP19 (show CYP19A1 Antibodies)), catechol-O-methyl transferase (COMT), sex hormone-binding globulin (SHBG (show SHBG Antibodies))and glutathione S-transferase (show GSTa2 Antibodies) (GSTP1 (show GSTP1 Antibodies)). Our data demonstrate that these ESR1 (show ESR1 Antibodies), GSTP1 (show GSTP1 Antibodies), and CYP19 (show CYP19A1 Antibodies) polymorphisms are associated with risk of BC, and the risk haplotype TGGGGTC could help to identify populations with high susceptibility to BC in Chinese women.

  4. No significant differences were found in COMT genotypes, allele frequencies, or haplotypes among migraine patient groups and controls.

  5. No association of functional polymorphisms in the estrogen metabolism genes COMT with menstrual migraine.

  6. genetic association studies in a population in Denmark: Data suggest that, compared to non-carriers of the COMT SNP rs4680 A allele, carriers/heterozygotes (AA/AG) report higher bone pressure pain tolerance threshold (i.e., less pain) by up to 23.8%.

  7. genetic association studies in a population in Denmark: Data suggest that a reduced risk of death in morphine addiction is associated with an SNP in ABCB1 (show ABCB1 Antibodies) (P-glycoprotein/ATP-binding cassette subfamily B (show CYP Antibodies) member 1, rs9282564, AG/TT) and an SNP in COMT (catechol-O-methyltransferase, rs4680, AA) in the population studied.

  8. COMT rs4680 influences individual differences in reward learning.

  9. COMT Val158Met polymorphism is not associated with endometrial and ovarian cancer.

  10. Whether COMT genotype indirectly influences global functional outcome through post-traumatic stress disorder remains to be determined

Mouse (Murine) Catechol-O-Methyltransferase (COMT) interaction partners

  1. This study report that genetically driven reduction in COMT enzyme activity increased cortical thickness in the prefrontal cortex (PFC (show CFP Antibodies)) and postero-parieto-temporal cortex of male, but not female adult mice.

  2. COMT expression in the hippocampus was significantly reduced by high E2 replacement, implying increased catecholamine levels in the hippocampus of high E2 mice.

  3. COMT overexpressing mice display an increase in dopamine release capacity in the striatum, suggesting increased COMT activity may affect dopamine signaling by enhancing synaptic clearance in the cortex and changes in striatal presynaptic dopamine function

  4. These data confirm at the level of mouse working memory and human working memory-associated physiology a genetic interaction between COMT and DTNBP1 (show DTNBP1 Antibodies).

  5. The results of this study suggest that individual differences in COMT activity do not affect primary reinforcing effects of cocaine in mice.

  6. Inhibition of COMT via serotonin binding contributes to pain hypersensitivity.

  7. COMT knockout mice were more impulsive compared with wild-type littermates.

  8. Data show that in male catechol-O-methyltransferase COMT(-/-)-mice, the total number of T-, and B-lymphocytes from spleen increased but the T-cell proliferative response decreased.

  9. decreased COMT activity was associated with some changes in feeding microstructure in rats and mice

  10. This study demonistrated that COMT deletion with elevated anxiety in females and suggest that this may be related to a heightened neuroendocrine response to acute stress in COMT KO mice.

COMT Antigen Profile

Antigen Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

Alternative names and synonyms associated with COMT

  • catechol-O-methyltransferase (COMT) antibody
  • catechol-O-methyltransferase (comt) antibody
  • catechol-O-methyltransferase (comt.2) antibody
  • catechol-o-methyltransferase (Rv1703c) antibody
  • catechol-o-methyltransferase (Mb1729c) antibody
  • catechol O-methyltransferase-like (LOC100630273) antibody
  • catechol-O-methyltransferase (Comt) antibody
  • comt antibody
  • Comt1 antibody
  • D16Wsu103e antibody
  • D330014B15Rik antibody
  • mb-comt antibody
  • MGC154444 antibody
  • s-comt antibody

Protein level used designations for COMT

catechol-O-methyltransferase , catechol-o-methyltransferase , catechol O-methyltransferase, soluble form , catechol O-methyltransferase, membrane-bound form , catechol O-methyltransferase , O-methyltransferase , catechol-O-methyltransferase 1 , catecholamine-O-methyltransferase

GENE ID SPECIES
416783 Gallus gallus
458655 Pan troglodytes
549111 Xenopus (Silurana) tropicalis
549911 Xenopus (Silurana) tropicalis
779254 Xenopus laevis
885066 Mycobacterium tuberculosis H37Rv
1092683 Mycobacterium bovis AF2122/97
100033869 Equus caballus
100146509 Equus caballus
100630273 Equus caballus
1312 Homo sapiens
445450 Canis lupus familiaris
12846 Mus musculus
24267 Rattus norvegicus
618278 Bos taurus
100155530 Sus scrofa
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