COMT antibody (Middle Region)

Catalog No. ABIN2781821

Product Details anti-COMT Antibody

Target: COMT (Catechol-O-Methyltransferase (COMT))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PDCAAITQRM VDFAGVKDKV TLVVGASQDI IPQLKKKYDV DTLDMVFLDH

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against COMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COMT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 271 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COMT

Target: COMT (Catechol-O-Methyltransferase (COMT))

Alternative Name: COMT (COMT Products)

Synonyms: Comt1 antibody, D16Wsu103e antibody, D330014B15Rik antibody, COMT antibody, mb-comt antibody, s-comt antibody, comt antibody, MGC154444 antibody, zgc:114157 antibody, si:dkey-13a21.15 antibody, zK13A21.15 antibody, zgc:162236 antibody, catechol-O-methyltransferase antibody, microRNA 4761 antibody, catechol-O-methyltransferase S homeolog antibody, methyltransferase antibody, catechol-o-methyltransferase antibody, catechol-O-methyltransferase a antibody, catechol-O-methyltransferase b antibody, catechol O-methyltransferase antibody, COMT antibody, Comt antibody, MIR4761 antibody, comt antibody, comt.2 antibody, comt.S antibody, Rv1703c antibody, Mb1729c antibody, comta antibody, comtb antibody, LOC100354142 antibody

Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathwa
Alias Symbols: -
Protein Interaction Partner: KRT40, TRIP13, UBC, KRT31, KRTAP5-9, CDC27, RNF2, FBXO6, vpr, FN1, VKORC1, VCP, RGS2, LITAF, XRN2, ACE,
Protein Size: 271

Molecular Weight: 30 kDa

Gene ID: 1312

NCBI Accession: NM_000754, NP_000745

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome