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anti-Rat (Rattus) GRIN2C Antibodies:
anti-Human GRIN2C Antibodies:
anti-Mouse (Murine) GRIN2C Antibodies:
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Mouse (Murine) Polyclonal GRIN2C Primary Antibody for WB - ABIN1881390
Krapivinsky, Krapivinsky, Manasian, Ivanov, Tyzio, Pellegrino, Ben-Ari, Clapham, Medina: The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1. in Neuron 2003
Show all 3 Pubmed References
Findings indicate that SNPs in the GRIN2C gene is associated with altered cue-induced brain activation that is related to craving for alcohol and relapse risk.
these findings highlight the isoform-specific structural and functional differences within the 14-3-3 (show YWHAQ Antibodies) family of proteins, which determine GluN2C binding and its essential role in targeting the receptor to the cell surface
NMDARs have a dual role during erythropoiesis, supporting survival of polychromatic erythroblasts and contributing to the Ca(2 (show CA2 Antibodies)+) homeostasis from the orthochromatic erythroblast stage to circulating red blood cells.
The major depression subjects exhibited significantly higher expression levels of the NMDA receptor subunit genes GRIN2C.
Reduction in NR1 (show GRIN1 Antibodies) and NR2C in the DLPFC of people with schizophrenia may lead to altered NMDAR (show GRIN1 Antibodies) stoichiometry and provides compelling evidence for an endogenous NMDAR (show GRIN1 Antibodies) deficit in schizophrenia.
TNFalpha (show TNF Antibodies) significantly upregulates NMDA-R2C mRNA expression, in differentiated, confluent, normal keratinocytes but not in involved or uninvolved psoriatic keratinocyte monolayers
Functional compensation could occur to counteract the loss of one allele in GRIN2C and GRIN3 (show GPRIN3 Antibodies) family genes.
The GluN2C subunit enhances ischemic stroke pathology by promoting neuronal dysfunction in the penumbra (show TSPAN33 Antibodies) region.
glutamatergic glial transmission is sensed by neurons of the dorsal Suprachiasmatic nucleus via specific pre-synaptic NMDA receptor assemblies containing NR2C subunits.
Tuberless heterozygote Tsc1 (show TSC1 Antibodies)+/- mice show functional up-regulation of cortical GluN2C receptors in an mTOR (show FRAP1 Antibodies)-dependent manner, exhibit recurrent, unprovoked seizures during early postnatal life, that can be treated with GluN2C antagonists.
low rectification normally observed in the nucleus reticularis of the thalamus is due to NR2C
No differences in expression of NR2A (show GRIN2A Antibodies), NR2C or NR2D (show GRIN2D Antibodies) are found in any brain region examined during ethanol consumption and acute ethanol withdrawal.
Study shows that the NR2C and Tiam1 (show TIAM1 Antibodies) maturation genes are synergistically controlled by the activity-dependent induction of Etv1 (show ETV1 Antibodies).
Findings suggest a unique role of NR2C-containing receptors in associative and executive learning. NR2C knockout mice were found to exhibit deficits in fear acquisition and working memory.
indicate that SNX27 (show SNX27 Antibodies) may function to regulate endocytosis and/or endosomal sorting of NR2C
Expression of GluRepsilon 3 is essential for postsynaptic localization and protein stability of the GluRzeta1 (show GRIN1 Antibodies) subunit.
The spiny stellate neurons of barrel cortex layer 4 functionally express NR2C subunits; this is the likely explanation for their ability to generate large NMDAR (show GRIN1 Antibodies)-mediated EPSPs that are effective at resting potential, without previous depolarization.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
, interleukin 12 receptor beta 2.b
, interleukin 12 receptor, beta 2a, like
, N-methyl-D-aspartate receptor subunit 2C
, ionotropic glutamate receptor subunit NR2C
, glutamate [NMDA] receptor subunit epsilon-3-like
, N-methyl D-aspartate receptor subtype 2C
, NMDA glutamate receptor
, glutamate [NMDA] receptor subunit epsilon-3
, glutamate receptor ionotropic, NMDA 2C
, glutamate receptor, ionotropic, NMDA2C