GRIN2C antibody (N-Term)

Catalog No. ABIN2776122

The Rabbit Polyclonal anti-GRIN2C antibody is suitable to detect GRIN2C in samples from Human, Rat, Mouse, Cow, Dog, Rabbit, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for GRIN2C antibody (N-Term) (ABIN2776122)

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GRIN2C Antibody

Binding Specificity: N-Term

Purpose: GRIN2C Antibody - N-terminal region

Sequence: VNTTNPSSLL TQICGLLGAA HVHGIVFEDN VDTEAVAQIL DFISSQTHVP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against GRIN2C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GRIN2C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101607

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRIN2C

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Alternative Name: GRIN2C

Background:

Targeted Subunit: epsilon-3

Background Information: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).

Gene Name: Glutamate receptor, ionotropic, N-methyl D-aspartate 2C

Alternative Symbols: NR2C, GluN2C, NMDAR2C

Protein Name: Glutamate [NMDA] receptor subunit epsilon-3

Molecular Weight: 134 kDa

Gene ID: 2905

NCBI Accession: NP_000826

UniProt: Q14957

Pathways: Synaptic Membrane