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GRK2 Antibodies

(Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008].
GRK2 antibody  (C-Term) GRK2 antibody  (C-Term) GRK2 antibody (C-Term) (ABIN2855125)

KO Validated ADRBK1 Reactivity: Human WB, IHC (p), IF, ICC, FACS, IP Host: Rabbit Polyclonal unconjugated

GRK2 antibody  (AA 440-689) GRK2 antibody  (AA 440-689) GRK2 antibody (AA 440-689) (ABIN3022346)

ADRBK1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

GRK2 antibody GRK2 antibody GRK2 antibody (ABIN969178)

ADRBK1 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, ICC Host: Mouse Monoclonal 3F8 unconjugated

GRK2 Antibodies by Grade

Find GRK2 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

GRK2 Antibodies by Reactivity

Find GRK2 Antibodies for a variety of species such as anti-Human GRK2, anti-Mouse GRK2, anti-Rat GRK2. The species listed below are among those available. Click on a link to go to the corresponding products.

GRK2 Antibodies by Application

Find GRK2 Antibodies validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

GRK2 Antibodies by Host

Find GRK2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

GRK2 Antibodies by Binding Specificity

Find GRK2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GRK2 Antibodies by Clonality

Find available monoclonal or polyclonal GRK2 Antibodies. Click on a link to go to the corresponding products.

GRK2 Antibodies by Clone

Find GRK2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

GRK2 Antibodies by Conjugate

Find GRK2 Antibodies with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GRK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC, FACS, IP
Validations
  • (6)
Cat. No. ABIN2855125
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN3022346
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7259288
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6259807
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (6)
  • (3)
Cat. No. ABIN1882061
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7265504
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Pig, Rat
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7294874
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN6655844
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Application WB
Validations
  • (3)
Cat. No. ABIN2784714
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7184989
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7184410
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7145433
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3184941
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN3184940
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN185583
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GRK2 Antibodies

Nakano, Onoue, Nakada, Nakagawa, Kumazawa, Ueda, Nishida, Soeda, Okayama, Watanabe, Kawata, Kawakami, Horii, Okura, Uemura, Hatakeyama, Sakaguchi, Saito: "Alteration of β-Adrenoceptor Signaling in Left Ventricle of Acute Phase Takotsubo Syndrome: a Human Study." in: Scientific reports, Vol. 8, Issue 1, pp. 12731, (2018) (PubMed).

Sterne-Marr, Leahey, Bresee, Dickson, Ho, Ragusa, Donnelly, Amie, Krywy, Brookins-Danz, Orakwue, Carr, Yoshino-Koh, Li, Tesmer: "GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail." in: Biochemistry, Vol. 48, Issue 20, pp. 4285-93, (2009) (PubMed).

Rao, Rapoport, Kim: "Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 6, pp. 851-60, (2009) (PubMed).

Chen, Long, Wu, Jiang, Ma: "EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation." in: Molecular biology of the cell, Vol. 19, Issue 7, pp. 2973-83, (2008) (PubMed).

Iaccarino, Barbato, Cipolletta, De Amicis, Margulies, Leosco, Trimarco, Koch: "Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure." in: European heart journal, Vol. 26, Issue 17, pp. 1752-8, (2005) (PubMed).

Eichmann, Lorenz, Hoffmann, Brockmann, Krasel, Lohse, Quitterer: "The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8052-7, (2003) (PubMed).

Li, Xiang, Su, Zhang, Huang, Ma: "Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30219-26, (2003) (PubMed).

Wan, Sambi, Tate, Waters, Pyne et al.: "The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated ..." in: The Journal of biological chemistry, Vol. 278, Issue 20, pp. 18658-63, (2003) (PubMed).

Yang, Zhang, Lai, Xing, Liu: "Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase." in: World journal of gastroenterology : WJG, Vol. 9, Issue 4, pp. 800-3, (2003) (PubMed).

Hagen, Kondyra, Grocott, El-Moalem, Bainbridge, Mathew, Newman, Reves, Schwinn, Kwatra: "Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells." in: Anesthesiology, Vol. 98, Issue 2, pp. 343-8, (2003) (PubMed).

Aliases for GRK2 Antibodies

beta-adrenergic receptor kinase 1 (Tsp_00497) Antibodies
G protein-coupled receptor kinase 2 (grk2) Antibodies
G protein-coupled receptor kinase 2 (Grk2) Antibodies
G protein-coupled receptor kinase 2 (GRK2) Antibodies
Adrbk-1 Antibodies
Bark-1 Antibodies
BARK1 Antibodies
BETA-ARK1 Antibodies
betaARK1 Antibodies
GRK-2 Antibodies
GRK2 Antibodies
Grk2 Antibodies
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