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Browse our anti-H2A Histone Family, Member X (H2AFX) Antibodies

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anti-H2A Histone Family, Member X Antibodies (H2AFX)
On are 347 H2A Histone Family, Member X (H2AFX) Antibodies from 32 different suppliers available. Additionally we are shipping H2A Histone Family, Member X Kits (15) and H2A Histone Family, Member X Proteins (9) and many more products for this protein. A total of 384 H2A Histone Family, Member X products are currently listed.
AW228881, gammaH2ax, h2a, h2a.x, h2a/x, h2afx, h2ax, Hist5-2ax, RGD1566119, zgc:56329
list all antibodies Gene Name GeneID UniProt
H2AFX 3014 P16104
H2AFX 15270 P27661
H2AFX 500987  

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All available anti-H2A Histone Family, Member X Antibodies

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Top referenced anti-H2A Histone Family, Member X Antibodies

  1. Human Polyclonal H2AFX Primary Antibody for ICC, IHC (fro) - ABIN152063 : Kaneko, Igarashi, Kataoka, Miura: Heat shock induces phosphorylation of histone H2AX in mammalian cells. in Biochemical and biophysical research communications 2005 (PubMed)
    Show all 22 references for ABIN152063

  2. Human Polyclonal H2AFX Primary Antibody for ICC, IF - ABIN151847 : Masutomi, Possemato, Wong, Currier, Tothova, Manola, Ganesan, Lansdorp, Collins, Hahn: The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 10 references for ABIN151847

  3. Human Monoclonal H2AFX Primary Antibody for BI, WB - ABIN967669 : Burma, Chen, Murphy, Kurimasa, Chen: ATM phosphorylates histone H2AX in response to DNA double-strand breaks. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN967669

  4. Human Monoclonal H2AFX Primary Antibody for WB - ABIN1882251 : Park, Chan, Park, Oettinger, Kwon: DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner. in Nucleic acids research 2003 (PubMed)
    Show all 5 references for ABIN1882251

  5. Human Polyclonal H2AFX Primary Antibody for IHC (p), WB - ABIN657639 : Jiang, Xu, Price: Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway. in FEBS letters 2010 (PubMed)
    Show all 3 references for ABIN657639

  6. Human Polyclonal H2AFX Primary Antibody for ICC, IF - ABIN2668328 : Velichko, Petrova, Kantidze, Razin: Dual effect of heat shock on DNA replication and genome integrity. in Molecular biology of the cell 2012 (PubMed)
    Show all 3 references for ABIN2668328

  7. Cow (Bovine) Polyclonal H2AFX Primary Antibody for WB - ABIN2787619 : Scherthan, Hieber, Braselmann, Meineke, Zitzelsberger: Accumulation of DSBs in gamma-H2AX domains fuel chromosomal aberrations. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN2787619

  8. Human Polyclonal H2AFX Primary Antibody for ELISA, WB - ABIN1531862 : Tyagi, Singh, Agarwal, Siriwardana, Sclafani, Agarwal: Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. in Carcinogenesis 2005 (PubMed)

  9. Human Polyclonal H2AFX Primary Antibody for IF (p), IHC (p) - ABIN742538 : Shi, Yang, Mao, Wu, Ren, Yang, Yin, Wei, Li, Wang: Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation. in Acta pharmacologica Sinica 2015 (PubMed)

More Antibodies against H2A Histone Family, Member X Interaction Partners

Human H2A Histone Family, Member X (H2AFX) interaction partners

  1. data cannot finally exclude H2AX methylation of SUV39H2 (show SUV39H2 Antibodies) in cells, additional experimental evidence is required to validate this claim.

  2. This review outlines the role of gamma-H2AX in cell cycle, and its formation as a result of DNA damage. We investigate the role of gamma-H2AX formation in several cancer types and its correlation with other prognostic factors, and we try to find out whether it fulfills the requirements for its establishment as a classical cancer prognostic factor

  3. dyserythropoiesis was increased in MDS patients with the deletion of chromosome 11q23, where H2AX is located. (show PAFAH1B1 Antibodies) Although loss of H2AX did not affect the early stage of terminal erythropoiesis, enucleation was decreased.

  4. the formation of 53BP1 (show TP53BP1 Antibodies), gammaH2AX foci and their co-localization induced by gamma-rays (2, 5, 10, 50, 200 cGy) in human lymphocytes, was analyzed.

  5. 5-Hydroxymethylcytosine (5hmC) accumulates at DNA damage foci and colocalizes with major DNA damage response proteins 53BP1 (show TP53BP1 Antibodies) and gH2AX, revealing 5hmC as an epigenetic marker of DNA damage.

  6. Anacardic acid sensitizes prostate cancer cells to radiation therapy by repressing H2AX expression.

  7. Results reveal a pathway controlled by ATM, SIRT6, and SNF2H to block HUWE1, which stabilizes H2AX and induces its incorporation into chromatin only when cells are damaged.

  8. Gene expression analysis identified deregulation of histone H2A and H2B genes in all four cell lines ;histone pathways are associated with epirubicin resistance

  9. kinetics of the accumulation of selected DNA repair-related proteins is protein specific at locally induced DNA lesions, and that the formation of gH2AX- and NBS1 (show NBN Antibodies)-positive foci, but not 53BP1 (show TP53BP1 Antibodies)-positive NBs (show NBN Antibodies), is cell cycle dependent in HeLa cells

  10. The interaction of MDC1 (show MDC1 Antibodies) with RNF8 (show RNF8 Antibodies), but not with ATM (show ATM Antibodies) requires WRAP53beta, suggesting that WRAP53beta facilitates the former interaction without altering phosphorylation of MDC1 (show MDC1 Antibodies) by ATM (show ATM Antibodies).

Mouse (Murine) H2A Histone Family, Member X (H2AFX) interaction partners

  1. Unlike directly induced DSBs, secondary DSBs were not efficiently repaired, although Rad51 (show RAD51 Antibodies) and 53BP1 (show TP53BP1 Antibodies) were recruited to these sites. H2AX was dramatically stabilized in response to DSBs directly caused by gamma-rays, enabling gammaH2AX foci formation and DSB repair, whereas H2AX was barely stabilized in response to secondary DSBs, in which gammaH2AX foci were small and DSBs were not efficiently repaired

  2. this study shows that T cells and thyrocytes in a mouse model of thyrocyte hyperplasia has foci of phosphorylated histone protein H2A.X, indicative of cellular senescence

  3. The role of H2AX phosphorylation and H3K56 acetylation on normal stem cell response to radiation

  4. H2AX knockout mice showed cell-autonomous anaemia and erythroid dysplasia, mimicking dyserythropoiesis in MDS (show MECOM Antibodies).

  5. These data suggest a role for FoxO3a in the maintenance of genome integrity in response to DNA damage that is mediated by H2AX via yet unknown mechanisms.

  6. overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation

  7. link gamma-H2AX to transcription, assigning a new function for this DNA damage marker

  8. DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylation of histone H2AX and its ubiquitination.

  9. Exposure to Cr(VI) induced villus blunting and crypt hyperplasia in the duodenum. gamma-H2AX immunostaining was elevated in villi, but not in the crypt compartment.

  10. Data indicate that crypts exposed to 180 ppm hexavalent chromium Cr(VI) appeared healthy and exhibited no difference in gammaH2ax (gamma-H2AX) staining relative to those of control.

Xenopus laevis H2A Histone Family, Member X (H2AFX) interaction partners

  1. These findings suggest a dimerize-then-rearrange model for H2A-H2B dimers.

  2. Findings reveal that XH2AX has a specific role in anterior neural formation of Xenopus, which is mediated through phosphorylation of XH2AX at Thr (show TRH Antibodies)(16) by Chk1 (show CHEK1 Antibodies).

Cow (Bovine) H2A Histone Family, Member X (H2AFX) interaction partners

  1. H2Ax phosphorylated protein was detected in in parthenogenetically activated, in vitro fertilized and cloned bovine embryos.

H2A Histone Family, Member X (H2AFX) Antigen Profile

Antigen Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Alternative names and synonyms associated with H2A Histone Family, Member X (H2AFX)

  • H2A histone family, member X (H2AFX) antibody
  • H2A histone family, member X (H2afx) antibody
  • H2A histone family, member X (h2afx) antibody
  • histone cluster 1, H2ah (HIST1H2AH) antibody
  • histone cluster 2, H2ab (hist2h2ab) antibody
  • histone H2A.x-like (LOC100522201) antibody
  • histone H2A.x-like (LOC100720536) antibody
  • AW228881 antibody
  • gammaH2ax antibody
  • h2a antibody
  • h2a.x antibody
  • h2a/x antibody
  • h2afx antibody
  • h2ax antibody
  • Hist5-2ax antibody
  • RGD1566119 antibody
  • zgc:56329 antibody

Protein level used designations for H2AFX

H2AX histone , histone H2A.x , H2a/x , histone 5 protein 2ax , H2A.X , histone H2A type 1

3014 Homo sapiens
15270 Mus musculus
394048 Danio rerio
734746 Xenopus laevis
531733 Bos taurus
500987 Rattus norvegicus
418708 Gallus gallus
444528 Xenopus laevis
100522201 Sus scrofa
100720536 Cavia porcellus
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