Browse our anti-H2A Histone Family, Member X (H2AFX) Antibodies

Full name:
anti-H2A Histone Family, Member X Antibodies (H2AFX)
On www.antibodies-online.com are 337 H2A Histone Family, Member X (H2AFX) Antibodies from 33 different suppliers available. Additionally we are shipping H2A Histone Family, Member X Kits (17) and H2A Histone Family, Member X Proteins (9) and many more products for this protein. A total of 376 H2A Histone Family, Member X products are currently listed.
Synonyms:
AW228881, gammaH2ax, h2a, h2a.x, h2a/x, h2afx, h2ax, Hist5-2ax, RGD1566119, zgc:56329
list all antibodies Gene Name GeneID UniProt
H2AFX 3014 P16104
H2AFX 15270 P27661
H2AFX 500987  

Show all species

Show all synonyms

All available anti-H2A Histone Family, Member X Antibodies

Go to our pre-filtered search.

Top referenced anti-H2A Histone Family, Member X Antibodies

  1. Human Polyclonal H2AFX Primary Antibody for ICC, IF - ABIN151847 : Masutomi, Possemato, Wong, Currier, Tothova, Manola, Ganesan, Lansdorp, Collins, Hahn: The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 10 references for 151847

  2. Human Monoclonal H2AFX Primary Antibody for BI, WB - ABIN967669 : Burma, Chen, Murphy, Kurimasa, Chen: ATM phosphorylates histone H2AX in response to DNA double-strand breaks. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for 967669

  3. Human Monoclonal H2AFX Primary Antibody for WB - ABIN1882251 : Park, Chan, Park, Oettinger, Kwon: DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner. in Nucleic acids research 2003 (PubMed)
    Show all 5 references for 1882251

  4. Human Polyclonal H2AFX Primary Antibody for ICC, IF - ABIN2668328 : Velichko, Petrova, Kantidze, Razin: Dual effect of heat shock on DNA replication and genome integrity. in Molecular biology of the cell 2012 (PubMed)
    Show all 3 references for 2668328

  5. Human Polyclonal H2AFX Primary Antibody for IHC (p), WB - ABIN657639 : Jiang, Xu, Price: Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway. in FEBS letters 2010 (PubMed)
    Show all 3 references for 657639

  6. Human Polyclonal H2AFX Primary Antibody for IF (p), IHC (p) - ABIN742538 : Shi, Yang, Mao, Wu, Ren, Yang, Yin, Wei, Li, Wang: Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation. in Acta pharmacologica Sinica 2015 (PubMed)
    Show all 2 references for 742538

  7. Cow (Bovine) Polyclonal H2AFX Primary Antibody for WB - ABIN2787619 : Scherthan, Hieber, Braselmann, Meineke, Zitzelsberger: Accumulation of DSBs in gamma-H2AX domains fuel chromosomal aberrations. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for 2787619

  8. Human Polyclonal H2AFX Primary Antibody for IHC, ELISA - ABIN1532893 : Tyagi, Singh, Agarwal, Siriwardana, Sclafani, Agarwal: Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. in Carcinogenesis 2005 (PubMed)

More Antibodies against H2A Histone Family, Member X Interaction Partners

Human H2A Histone Family, Member X (H2AFX) interaction partners

  1. study demonstrates that the individual and combined expression patterns of the DDR (show DDR1 Antibodies) molecules PARP1 (show PARP1 Antibodies), gammaH2AX, BRCA1, and BRCA2 (show BRCA2 Antibodies) could be predictive of the prognosis of STS (show STS Antibodies) patients and suggests that controlling the activity of these DDR (show DDR1 Antibodies) molecules could be employed in new therapeutic stratagems for the treatment of STS (show STS Antibodies)

  2. Further analysis suggested that H2AX, a PARP-1 (show PARP1 Antibodies) protein interaction partner, was coordinated with PARP-1 (show PARP1 Antibodies) in hepatocellular carcinoma tumorigenesis. Overall, some new characteristics of PARP-1 (show PARP1 Antibodies) expression were noted in the Zhuang population. PARP-1 (show PARP1 Antibodies) is a novel promising diagnostic marker for hepatocellular carcinoma in the Southern Chinese Zhuang population

  3. we found that gamma-H2AX foci at chromosome boundaries after carbon-ion irradiation contain DNA double strand breaks undergoing DNA-end resection, which promotes repair utilizing microhomology mediated end-joining during translocation.

  4. this study demonstrates an early DDR (show DDR1 Antibodies) defect of attenuated gammaH2AX signals in G0/G1 phase HGPS (show Zmpste24 Antibodies) cells and provides a plausible connection between H3K9me3 loss and DDR (show DDR1 Antibodies) deficiency.

  5. Data indicate an important role for histone H2A.X (H2AX) Tyr39 phosphorylation in gamma-H2A.X formation and cancer progression.

  6. we suggest that the XAB2 (show XAB2 Antibodies) complex mediates DNA damage response events important for the end resection step of homologous recombination , and speculate that its adjacent-localization relative to double-strand break marked by gH2AX is important for this function

  7. the epithelial-mesenchymal transition-related transcription factor Twist1 (show TWIST1 Antibodies) cooperates with Slug (show SNAI2 Antibodies) to regulate EMT (show ITK Antibodies) upon H2A.X Loss.

  8. Upon DNA damage, an increase in the levels of chromatin bound motor protein nuclear myosin 1 (NM1 (show MYO1C Antibodies)) ensues, which appears to be functionally linked to Upsilon-H2AX signaling.

  9. TRAF6 (show TRAF6 Antibodies) and H2AX overexpression and gammaH2AX-mediated HIF1alpha (show HIF1A Antibodies) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (show HIF1A Antibodies)-driven tumorigenesis, glycolysis and metastasis.

  10. gammaH2AX, claimed to be a marker of DNA double-strand breaks, was found in cell extracts of HeLa cells at elevated temperature vs. 37.0 degrees C, and these gammaH2AX signals were intensified in the presence of 3-aminobenzamide, a PARP (show COL11A2 Antibodies) inhibitor.

Mouse (Murine) H2A Histone Family, Member X (H2AFX) interaction partners

  1. TRAF6 (show TRAF6 Antibodies) and H2AX overexpression and gammaH2AX-mediated HIF1alpha (show HIF1A Antibodies) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (show HIF1A Antibodies)-driven tumorigenesis, glycolysis and metastasis.

  2. The findings highlight specific non-overlapping functions of PARP1 (show PARP1 Antibodies) and PARP2 (show PARP2 Antibodies) at H2AX-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 (show PARP1 Antibodies) in nonhomologous end-joining-deficient cells.

  3. Unlike directly induced DSBs, secondary DSBs were not efficiently repaired, although Rad51 (show RAD51 Antibodies) and 53BP1 (show TP53BP1 Antibodies) were recruited to these sites. H2AX was dramatically stabilized in response to DSBs directly caused by gamma-rays, enabling gammaH2AX foci formation and DSB repair, whereas H2AX was barely stabilized in response to secondary DSBs, in which gammaH2AX foci were small and DSBs were not efficiently repaired

  4. this study shows that T cells and thyrocytes in a mouse model of thyrocyte hyperplasia has foci of phosphorylated histone protein H2A.X, indicative of cellular senescence

  5. The role of H2AX phosphorylation and H3K56 acetylation on normal stem cell response to radiation

  6. H2AX knockout mice showed cell-autonomous anaemia and erythroid dysplasia, mimicking dyserythropoiesis in MDS (show MECOM Antibodies).

  7. These data suggest a role for FoxO3a in the maintenance of genome integrity in response to DNA damage that is mediated by H2AX via yet unknown mechanisms.

  8. overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation

  9. link gamma-H2AX to transcription, assigning a new function for this DNA damage marker

  10. DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylation of histone H2AX and its ubiquitination.

Xenopus laevis H2A Histone Family, Member X (H2AFX) interaction partners

  1. These findings suggest a dimerize-then-rearrange model for H2A-H2B dimers.

  2. Findings reveal that XH2AX has a specific role in anterior neural formation of Xenopus, which is mediated through phosphorylation of XH2AX at Thr (show TRH Antibodies)(16) by Chk1 (show CHEK1 Antibodies).

Cow (Bovine) H2A Histone Family, Member X (H2AFX) interaction partners

  1. H2Ax phosphorylated protein was detected in in parthenogenetically activated, in vitro fertilized and cloned bovine embryos.

H2A Histone Family, Member X (H2AFX) Antigen Profile

Antigen Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Alternative names and synonyms associated with H2A Histone Family, Member X (H2AFX)

  • H2A histone family, member X (H2AFX) antibody
  • H2A histone family, member X (H2afx) antibody
  • H2A histone family, member X (h2afx) antibody
  • histone cluster 1, H2ah (HIST1H2AH) antibody
  • histone cluster 2, H2ab (hist2h2ab) antibody
  • histone H2A.x-like (LOC100522201) antibody
  • histone H2A.x-like (LOC100720536) antibody
  • AW228881 antibody
  • gammaH2ax antibody
  • h2a antibody
  • h2a.x antibody
  • h2a/x antibody
  • h2afx antibody
  • h2ax antibody
  • Hist5-2ax antibody
  • RGD1566119 antibody
  • zgc:56329 antibody

Protein level used designations for H2AFX

H2AX histone , histone H2A.x , H2a/x , histone 5 protein 2ax , H2A.X , histone H2A type 1

GENE ID SPECIES
3014 Homo sapiens
15270 Mus musculus
394048 Danio rerio
734746 Xenopus laevis
531733 Bos taurus
500987 Rattus norvegicus
418708 Gallus gallus
444528 Xenopus laevis
100522201 Sus scrofa
100720536 Cavia porcellus
Selected quality suppliers for anti-H2A Histone Family, Member X (H2AFX) Antibodies
Did you look for something else?