H2AFX Products
(H2A Histone Family, Member X (H2AFX))
Categories
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].
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Featured H2AFX Categories
H2AFX Antibodies
High quality antibodies with extensive validation data.
H2AFX ELISA Kits
Reliable ELISA kits for a wide range of species.
H2AFX Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended H2AFX Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN7007527
Quantity
60 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, ChIP
Validations
- (5)
Cat. No.
ABIN7139642
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (4)
Cat. No.
ABIN1882250
Quantity
200 μL
Datasheet
Datasheet
Recommended H2AFX ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967277
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956383
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380601
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended H2AFX Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123247
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306292
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306291
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our H2AFX products
: "MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis." in: Molecular cell, Vol. 74, Issue 3, pp. 571-583.e8, (2019) (PubMed).: "Reactive oxygen species induced by icaritin promote DNA strand breaks and apoptosis in human cervical cancer cells." in: Oncology reports, Vol. 41, Issue 2, pp. 765-778, (2019) (PubMed).
: "The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice." in: The Journal of biological chemistry, Vol. 292, Issue 52, pp. 21490-21503, (2018) (PubMed).
: "CAPER as a therapeutic target for triple negative breast cancer." in: Oncotarget, Vol. 9, Issue 54, pp. 30340-30354, (2018) (PubMed).
: "Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT." in: Frontiers in immunology, Vol. 9, pp. 631, (2018) (PubMed).
: "Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma." in: Molecular cancer research : MCR, Vol. 16, Issue 9, pp. 1406-1419, (2018) (PubMed).
: "Dihydroartemisinin induces autophagy-dependent death in human tongue squamous cell carcinoma cells through DNA double-strand break-mediated oxidative stress." in: Oncotarget, Vol. 8, Issue 28, pp. 45981-45993, (2018) (PubMed).
: "Shikonin alleviates the biotoxicity produced by pneumococcal pneumolysin." in: Life sciences, Vol. 177, pp. 1-7, (2017) (PubMed).
: "Morin Moderates the Biotoxicity of Pneumococcal Pneumolysin by Weakening the Oligomers' Formation." in: Chemical & pharmaceutical bulletin, Vol. 65, Issue 6, pp. 538-544, (2017) (PubMed).
: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
Synonyms and alternative names related to H2AFX
H2A histone family member X (H2AFX), H2A histone family, member X (H2afx), H2A histone family, member X (h2afx), H2A histone family member X L homeolog (h2afx.L), H2A histone family, member X (H2AFX), histone cluster 1, H2ah (HIST1H2AH), histone cluster 2, H2ab S homeolog (hist2h2ab.S), histone H2AX (LOC100522201), histone H2AX (LOC100720536), AW228881, gammaH2ax, h2a, H2A.X, h2a.x, H2A/X, h2a/x, h2afx, H2AX, H2ax, h2ax, Hist5-2ax, RGD1566119, zgc:56329Protein level used designations for H2AFX
- H2AX histone
- histone H2A.x
- H2a/x
- histone 5 protein 2ax
- H2A.X
- histone H2A type 1
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