4-Hydroxyphenylpyruvate Dioxygenase Proteins (HPD)

The protein encoded by HPD is an enzyme in the catabolic pathway of tyrosine. Additionally we are shipping HPD Antibodies (108) and HPD Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HPD 29531 P32755
HPD 3242 P32754
HPD 15445 P49429
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Top HPD Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,227.64
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,227.64
Details
Escherichia coli (E. coli) Human His tag   50 μg 4 Days
$377.30
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg 4 to 8 Days
$396.00
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Escherichia coli (E. coli) Human His tag 50 μg 15 to 19 Days
$646.15
Details
Yeast Streptomyces coelicolor His tag   1 mg 60 to 71 Days
$3,048.83
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$3,081.83
Details
Yeast Cow His tag   1 mg 60 to 71 Days
$3,081.83
Details

HPD Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , , ,
, , ,
Mouse (Murine)

More Proteins for 4-Hydroxyphenylpyruvate Dioxygenase (HPD) Interaction Partners

Human 4-Hydroxyphenylpyruvate Dioxygenase (HPD) interaction partners

  1. The mutagenesis and structural simulation studies demonstrate the critical and unique role of each ligand in the function of HPPD, and which correlates with their respective co-ordination position.

  2. 4-hydroxyphenylpyruvate dioxygenase gene mutation is associated with Hawkinsinuria.

  3. Glutamine375 has a critical role for 4-HPPD in orientating the tail and ensuring the conformation of the terminal alpha-helix of the enzyme to maintain the integrity of the active site for biocatalysis.

  4. The IIe335Met allele is equivalent to a null mutation while the Asn241Ser allele results in a partially active enzyme with an uncoupled turnover causing elevated haykinin in urine.

Mouse (Murine) 4-Hydroxyphenylpyruvate Dioxygenase (HPD) interaction partners

  1. The findings reveal a previously unknown regulation of 4-hydroxyphenylpyruvic acid dioxygenase (HPD) expression and highlight the physiological significance of TTC36-STK33-PELI1-regulated HPD expression in tyrosinemia and tyrosinemia-associated neurological disorders.

  2. We observed long-term postnatal persistence of edited cells in both models, with reduction of plasma PCSK9 and cholesterol levels following in utero Pcsk9 targeting and rescue of the lethal phenotype of hereditary tyrosinemia type 1 following in utero Hpd targeting

  3. Gene expressions in tyrosinemia type I model mice with liver failure using microarrays. Numerous genes, including amino acid metabolism and apoptosis related genes, were up- or down-regulated at the onset of liver failure.

HPD Protein Profile

Protein Summary

The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HPD

  • 4-hydroxyphenylpyruvate dioxygenase a (hpda)
  • 4-hydroxyphenylpyruvate dioxygenase (HPD)
  • 4-hydroxyphenylpyruvate dioxygenase b (hpdb)
  • 4-hydroxyphenylpyruvate dioxygenase L homeolog (hpd.L)
  • 4-hydroxyphenylpyruvate dioxygenase (hpd)
  • 4-hydroxyphenylpyruvate dioxygenase (BA_0240)
  • 4-hydroxyphenylpyruvate dioxygenase (hppD)
  • 4-hydroxyphenylpyruvate dioxygenase (Hpd)
  • 4-hydroxyphenylpyruvate dioxygenase (PDS1)
  • 4-hydroxyphenylpyruvic acid dioxygenase (Hpd)
  • 4-HPPD protein
  • 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE protein
  • 4HPPD protein
  • BA0240 protein
  • DDBDRAFT_0203373 protein
  • DDBDRAFT_0231603 protein
  • DDBDRAFT_0231604 protein
  • DDB_0203373 protein
  • DDB_0231603 protein
  • DDB_0231604 protein
  • F12K11.9 protein
  • F12K11_9 protein
  • fb58f02 protein
  • Fla protein
  • Flp protein
  • GLOD3 protein
  • HPD protein
  • Hppd protein
  • HPPDASE protein
  • Laf protein
  • MGC146689 protein
  • P-HYDROXYPHENYLPYRUVATE DIOXYGENASE protein
  • phytoene desaturation 1 protein
  • PPD protein
  • PSPTO3553 protein
  • wu:fb58f02 protein
  • zgc:56326 protein
  • zgc:92456 protein

Protein level used designations for HPD

4-hydroxyphenylpyruvate dioxygenase , 4HPPD , HPPDase , 4-hydroxyphenylpyruvic acid oxidase , p-hydroxyphenylpyruvic hydroxylase , 4-hydroxyphenylpyruvic acid dioxygenase , f Alloantigen , f protein , glyoxalase domain containing 3 , F liver antigen

GENE ID SPECIES
394142 Danio rerio
416852 Gallus gallus
445287 Danio rerio
473296 Pan troglodytes
495029 Xenopus laevis
594976 Xenopus (Silurana) tropicalis
610778 Canis lupus familiaris
700940 Macaca mulatta
779829 Xenopus (Silurana) tropicalis
1086140 Bacillus anthracis str. Ames
1169722 Shewanella oneidensis MR-1
1185218 Pseudomonas syringae pv. tomato str. DC3000
3193684 Ruegeria pomeroyi DSS-3
4382844 Pseudomonas aeruginosa UCBPP-PA14
8621032 Dictyostelium discoideum AX4
8995781 Salinibacter ruber M8
100021685 Monodelphis domestica
100195397 Salmo salar
100347363 Oryctolagus cuniculus
29531 Rattus norvegicus
3242 Homo sapiens
516058 Bos taurus
397443 Sus scrofa
837168 Arabidopsis thaliana
15445 Mus musculus
Selected quality suppliers for HPD Proteins (HPD)
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