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anti-5'-Nucleotidase, Cytosolic III (NT5C3) Antibodies

NT5C3 encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. Additionally we are shipping 5'-Nucleotidase, Cytosolic III Proteins (10) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NT5C3 107569 Q9D020
NT5C3 51251 Q9H0P0
NT5C3 312373  
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Top anti-5'-Nucleotidase, Cytosolic III Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NT5C3 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat/COLO205 cells, using NT5C3 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NT5C3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis on Jurkat cell lysate using NT5C3 Antibody,The lane on the left is treated with the antigen-specific peptide. ABIN6266817 at 1/100 staining human Lymph node tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Liver Tissue; Lane2: Human Lung Tissue; Lane3: Rat Heart Tissue. 100 μg 15 to 18 Days
$350.00
Details
Human Rabbit Un-conjugated WB Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: U-2OS whole cell lysate Lane 6: SH-SY5Y whole cell lysate Lysates/proteins at 20 ug per lane. 200 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, IP, WB 100 μL 14 to 16 Days
$247.82
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded stomach tissue 100 μg 15 to 18 Days
$360.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg 13 to 16 Days
$380.00
Details

Top referenced anti-5'-Nucleotidase, Cytosolic III Antibodies

  1. Human Polyclonal NT5C3 Primary Antibody for IHC, IHC (p) - ABIN4340799 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against 5'-Nucleotidase, Cytosolic III Interaction Partners

Mouse (Murine) 5'-Nucleotidase, Cytosolic III (NT5C3) interaction partners

  1. report describes the first X-ray structure of a catalytically inactivated variant of murine cN-III with a natural substrate, uridine 5'-monophosphate, in the active site at 1.74A resolution

Human 5'-Nucleotidase, Cytosolic III (NT5C3) interaction partners

  1. Data indicate an anti-inflammatory pathway that depends on the catalytic activity of pyrimidine 5'-nucleotidase (NT5C3A) and functions as a negative feedback regulator of inflammatory cytokine signaling.

  2. Results from a study on gene expression variability markers in early-stage human embryos shows that NT5C3A is a putative expression variability marker for the 3-day, 8-cell embryo stage.

  3. reduced expression of transketolase in pyrimidine 5'-nucleotidase deficient patients

  4. Pyrimidine-5'-nucleotidase Campinas is a new mutation (p.R56G) in the NT5C3 gene associated with pyrimidine-5'-nucleotidase type I deficiency.

  5. Results show that NT5C3 expression levels were significantly increased in patients with risk allele homozygote.

  6. New missense homozygous mutation (Q270Ter) in the pyrimidine 5' nucleotidase type I-related gene in two Indian families with hereditary non-spherocytic hemolytic anemia.

  7. analysis of Drosophila and human 7-methyl GMP-specific nucleotidases

  8. Data show that PN-I shows a higher affinity for oxynucleosides rather than deoxynucleosides, while the opposite is true for PN-II.

  9. All investigated mutant proteins display impaired catalytic properties and/or reduced thermostability, providing a rationale for the pathological effects of the mutations.

  10. These data highlight hUMP1/POMP role in proteasome assembly and further strengthen the prospect of genetic manipulation of the proteasomal system.

  11. 3 newly described missense mutations (c.187T>C, c.469G>C & c.740T>C) identified in patients with hemolytic anemia were characterized at protein level; the enzymes were altered in both thermal stability and catalytic efficiency

  12. In leukoblasts from 82 patients with acute myeloid leukemia, various extent and frequency of differential allelic expression in the CDA, DCK, NT5C2, NT5C3, and TP53 genes was observed.

  13. genetic variation in NT5C3 might affect protein function and potentially influence drug response

5'-Nucleotidase, Cytosolic III (NT5C3) Antigen Profile

Protein Summary

This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.

Gene names and symbols associated with NT5C3

  • 5'-nucleotidase, cytosolic III (Nt5c3) antibody
  • 5'-nucleotidase, cytosolic IIIA (nt5c3a) antibody
  • 5'-nucleotidase, cytosolic IIIA (NT5C3A) antibody
  • cytosolic 5'-nucleotidase 3A (LOC534181) antibody
  • 5'-nucleotidase, cytosolic IIIA (Nt5c3a) antibody
  • 5'-nucleotidase, cytosolic IIIA (nt5c3a.L) antibody
  • 5'-nucleotidase, cytosolic III (Bm1_56095) antibody
  • 1600024P05Rik antibody
  • 2610206B05Rik antibody
  • 3110004A18Rik antibody
  • AI842776 antibody
  • cN-III antibody
  • fb30h07 antibody
  • hUMP1 antibody
  • lupin antibody
  • Nt5c3 antibody
  • Nt5c3a antibody
  • Nt5y antibody
  • P5'N-1 antibody
  • P5N-1 antibody
  • p36 antibody
  • PN-1 antibody
  • PN-I antibody
  • POMP antibody
  • PSN1 antibody
  • PYN1 antibody
  • UMPH antibody
  • Umph-1 antibody
  • UMPH1 antibody
  • wu:fb30h07 antibody
  • zgc:66117 antibody

Protein level used designations for NT5C3

5'-nucleotidase, pyrimidine , P5'N-1 , P5N-1 , cytosolic 5'-nucleotidase 3 , cytosolic 5'-nucleotidase 3A , cytosolic 5'-nucleotidase III , pyrimidine 5'-nucleotidase 1 , uridine monophosphatase 1 , 5'-nucleotidase, cytosolic III , cN-III , PN-I , lupin , uridine 5'-monophosphate hydrolase 1

GENE ID SPECIES
107569 Mus musculus
321720 Danio rerio
395080 Gallus gallus
472343 Pan troglodytes
534181 Bos taurus
51251 Homo sapiens
475277 Canis lupus familiaris
312373 Rattus norvegicus
494724 Xenopus laevis
6106102 Brugia malayi
100145170 Xenopus (Silurana) tropicalis
100055382 Equus caballus
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