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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell.
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Human Polyclonal AKAP3 Primary Antibody for ELISA, WB - ABIN250200
Lefevre, Duquenne, Rousseau-Merck, Rogier, Finaz: Cloning and characterization of SOB1, a new testis-specific cDNA encoding a human sperm protein probably involved in oocyte recognition. in Biochemical and biophysical research communications 1999
AKAP3 correlates with triple negative status and disease free survival in breast cancer.
study reports the isolation of AKAP3 and CTp11 (show SPANXC Antibodies) Cancer/testis antigens from hepatocellular carcinoma patient sera
CABYR (show CABYR Antibodies) variants form a complex not only with the scaffolding protein AKAP3 but also with another RII-like domain-containing protein in the sperm fibrous sheath.
In Cox (show COX8A Antibodies) multivariate analysis, AKAP3 mRNA expression was found to be a significant predictor of both overall and progression-free survival in patients with poorly differentiated tumors.
AKAP-3 demonstrates tumor-restricted expression and appears to be associated with worse overall survival.
AKAP3 is a novel target for protein S-nitrosylation in spermatozoa.
Studied PKA subunit isoform expression in meiotic and post-meiotic mouse spermatogenic cells, and found sperm-specific AKAP3 can be found in the cytoplasm of elongating spermatids and interacts with RIalpha (show PRKAR1A Antibodies).
We analyzed the expression of sperm-specific Akap3 and the potential regulatory factors of its protein synthesis during mouse spermiogenesis.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
A kinase (PRKA) anchor protein 3
, A-kinase anchor protein 3
, A-kinase anchor protein 3-like
, a-kinase anchor protein 3-like
, A-kinase anchor protein, 110kDa
, Fibrous Sheath Protein of 95 kDa
, cancer/testis antigen 82
, fibrousheathin I
, protein kinase A binding protein AKAP 110
, protein kinase A-anchoring protein 3
, sperm oocyte-binding protein 1
, A-kinase anchor protein 110 kDa
, AKAP 110
, Protein kinase A-anchoring protein 3