A Kinase (PRKA) Anchor Protein 4 Proteins (AKAP4)

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. Additionally we are shipping AKAP4 Antibodies (40) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AKAP4 8852 Q5JQC9
AKAP4 11643 Q60662
AKAP4 79254 O35774
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Top AKAP4 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,916.00
Details

AKAP4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for A Kinase (PRKA) Anchor Protein 4 (AKAP4) Interaction Partners

Human A Kinase (PRKA) Anchor Protein 4 (AKAP4) interaction partners

  1. High AKAP4 expression is associated with reduced sperm motility.

  2. A significant association was found between AKAP4 gene expression and metastasis (P-value: 0.045), expression of the CTAG1B (NY-ESO-1) gene was not observed in our cases.

  3. the physiological role of the negative crosstalk between the cAMP/PKA/AKAP4 and the PKC/ERK1/2 pathways is to regulate capacitation and acrosome reaction.

  4. AKAP4 role in the proliferation and metastasis of thyroid cancer.AKAP4 is highly expressed in thyroid cancer.

  5. AKAP4 appears to be a novel Colorectal cancer-associated antigen with a potential for developing as a new clinical therapeutic target

  6. AKAP4 is a highly accurate biomarker for the detection of early stage lung cancer.

  7. SP17/AKAP4/PTTG1 are expressed in both human NSCLC cell lines and primary tumors and can elicit an immunogenic response in lung cancer patients.

  8. The putative role of AKAP4 in early tumorigenesis is implicated as a biomarker and immunotherapeutic target for cervical cancer.

  9. Ablation of AKAP4 protein caused significant inhibition in cellular proliferation, colony-forming ability, migration and invasion ability of tumor cells.

  10. data suggests that AKAP4 may be used as serum based diagnostic test for an early detection and diagnosis of breast cancer and may be a potential target for immunotherapeutic use

  11. We demonstrate the aberrant expression of AKAP-4 in prostate cancer, which will potentially be developed as a biomarker in prostate cancer.

  12. AKAP4 is a novel target for protein S-nitrosylation in spermatozoa.

  13. Role of AKAP4 in sperm motility is unclear, vut absent or weak AKAP4-labelling is associated with absent or weak sperm. motility.

Mouse (Murine) A Kinase (PRKA) Anchor Protein 4 (AKAP4) interaction partners

  1. we validated the use of AKAP-4 antigen to track tumor growth in vivo and to specifically identify MM cells in mouse tissues.

  2. Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility.

  3. AKAP4 has a major role in completing fibrous sheath assembly

  4. the distribution of AKAP4 was dependent on the microtubular cytoskeleton.

AKAP4 Protein Profile

Protein Summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene names and symbols associated with AKAP4

  • A-kinase anchoring protein 4 (AKAP4)
  • A kinase (PRKA) anchor protein 4 (Akap4)
  • A-kinase anchoring protein 4 (Akap4)
  • AKAP-4 protein
  • AKAP4 protein
  • AKAP 82 protein
  • AKAP82 protein
  • CT99 protein
  • Fsc1 protein
  • hAKAP82 protein
  • HI protein
  • p82 protein
  • PRKA4 protein

Protein level used designations for AKAP4

A-kinase anchor protein 4 , A kinase (PRKA) anchor protein 4 , A-kinase anchor protein 82 kDa , cancer/testis antigen 99 , major sperm fibrous sheath protein , protein kinase A anchoring protein 4 , protein kinase A-anchoring protein 4 , testis-specific gene HI , AKAP 82 , AKAP-4 , PRKA4 , mAKAP82 , 75 kDa fibrous sheath protein

GENE ID SPECIES
281611 Bos taurus
465971 Pan troglodytes
480917 Canis lupus familiaris
100582108 Nomascus leucogenys
8852 Homo sapiens
11643 Mus musculus
79254 Rattus norvegicus
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