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AKIP1 encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Additionally we are shipping AKIP1 Antibodies (46) and many more products for this protein.
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The absence of exon 3 and exon 5 influenced the subcellular localization of BCA3 and nuclear factor kappa B (NF-kB)-dependent gene expression.
Data indicate an important role for A-kinase-interacting protein 1 (AKIP1) in esophageal squamous cell carcinoma (ESCC) angiogenesis and lymphangiogenesis.
Expression of BCA3 did not affect Mason-Pfizer money virus (MPMV) particle release and proteolytic processing; however, it slightly increased MPMV infectivity.
Data indicate A-kinase interacting protein 1 (AKIP1) as a critical molecular regulator and a therapeutic control point for stress adaptation in the heart.
action of PKA signaling on the NF-kappaB (show NFKB1 Proteins) activation cascade
characterization of the BCA3 gene; BCA3 is expressed in breast tumor cells in vivo, and not in surrounding stromal tissue
AKIP1 describes a PKA-interacting protein that can contribute to localization by a mechanism that is distinct from A-kinase anchoring proteins that interact with the regulatory subunits.
AKIP1 colocalized with p65 (show GORASP1 Proteins) within the cells and appeared to retain p65 (show GORASP1 Proteins) in nucleus.
AKIP1 overexpression does not influence cardiac remodelling in response to chronic cardiac stress, or heart failure development. AKIP1 does, however, reduce myocardial I/R injury through stabilization of the MPT pore.
This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene.
A-kinase-interacting protein 1
, breast cancer associated gene 3
, koyt binding protein 1
, koyt binding protein 2
, koyt binding protein 3
, proline-rich protein BCA3
, PKA-interacting protein
, breast cancer associated 3
, breast cancer-associated gene 3 protein
, protein kinase A-interacting protein 1