anti-ADAM Metallopeptidase Domain 28 (ADAM28) Antibodies

ADAM28 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Additionally we are shipping ADAM28 Kits (9) and ADAM28 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAM28 290344  
ADAM28 13522 Q9JLN6
ADAM28 10863 Q9UKQ2
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Top anti-ADAM28 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of ADAM28 expression in A549 (A), Raw264.7 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of ADAM28 using anti-ADAM28 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: HELA whole cell lysates, Lane 2: K562 whole cell lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-ADAM28 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for ADAM28 at approximately 87/61KD. The expected band size for ADAM28 is at 87KD. 100 μg 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ADAM28 using COLO205 whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ICC, IHC, WB 100 μL 13 to 16 Days
$245.00
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-ADAM28 Polyclonal Antibody, Unconjugated (ABIN758861) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse Blood Cells probed with ADAM28 Polyclonal Antibody, Unconjugated  (green) at 1:30 for 30 minutes followed by a FITC conjugated secondary antibody compared to unstained cells (blue), secondary only (light blue), and isotype control (orange). 100 μL 3 to 7 Days
$339.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using ADAM28 antibody. 100 μL 11 to 13 Days
$363.06
Details
Human Rabbit Alexa Fluor 594 FACS, IF (p)   100 μL 14 to 21 Days
$442.20
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$390.50
Details
Human Rabbit Cy3 FACS, IF (p)   100 μL 14 to 21 Days
$442.20
Details
Human Rabbit FITC FACS, IF (p)   100 μL 14 to 21 Days
$442.20
Details

Top referenced anti-ADAM28 Antibodies

  1. Human Polyclonal ADAM28 Primary Antibody for FACS, IF (p) - ABIN758861 : Zhang, Zhu, Xiao, Liu, Han, Chen, Hou, Shen, Li, Ma, Wang: CD19 regulates ADAM28-mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells. in Journal of cellular and molecular medicine 2017 (PubMed)

More Antibodies against ADAM28 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 28 (ADAM28) interaction partners

  1. The results suggest that CD19 controls the differentiation of marginal zone precursors to marginal zone B cells by regulating ADAM28-mediated Notch2 cleavage.

  2. The authors report that recombinant human MDC-L (ADAM 28) protein with the disintegrin domain binds to the alpha(4)beta(1) integrin, and this binding may regulate the interaction between lymphocytes and leukocytes expressing alpha(4)beta(1).

Human ADAM Metallopeptidase Domain 28 (ADAM28) interaction partners

  1. ADAM28 regulates the growth and dissemination of acute myeloid leukemia through IGFBP-3 degradation and IGF-I-induced cell proliferation.

  2. Within placental villi, ADAM28 mRNA levels were highest in HLA-G(+) column trophoblasts, and consistent with this, ADAM28 was preferentially localized to HLA-G(+) trophoblasts within distal anchoring columns and decidual tissue.

  3. There is a relationship between the serum level of ADAM28 and the degree of the colonic cancer clinical stage.

  4. miR-552 is an oncomir able to promote CRC metastasis in part through a mechanism of targeting ADAM28.

  5. The data demonstrate that ADAM28 is expressed by epithelial cells of several normal organs, and suggest that ADAM28 plays a role in cell survival by suppression of C1q-induced cytotoxicity in bronchial epithelial cells.

  6. ADAM28 is overexpressed in primary human prostate tumor biopsies, and it promotes human prostate cancer cell proliferation and migration.

  7. The results of this study suggest that these proteins play important roles in pulmonary inflammatory reactions elicited against etiological viral agents.

  8. Src is an inducer of ADAM28 gene expression through the MEK/extracellular signal-regulated kinase and PI3K/mammalian target of rapamycin pathways.

  9. IL-1beta-induced MMP-13 expression and changes in cell proliferation and apoptosis in alpha7(+)hSMSC-OB cells are regulated by ADAM-28.

  10. Sequence analysis of ADAM28 genes did not reveal any putative mutations for hyperostosis cranialis interna to chromosome 8p21

  11. The change of ADAM28 and IGFBP-3 gene expression is present in the normal tissue in overweight/obese patients with colorectal cancer only, and the observed variability of ADAM28 and IGFBP-3 expression may be an initial process of cancer proliferation

  12. High ADAM28 expression is associated with B-Cell Chronic Lymphocytic Leukemia.

  13. Human ADAM28 expression levels were positively correlated with parameters of the metabolic syndrome.

  14. ADAM28 cleaves and inactivates proapoptotic VWF in carcinoma cells and enhances lung metastasis probably by promoting carcinoma cell survival within the blood vessels.

  15. Study shows using proteomics that ADAM28 may be used as a possible biomarker of bladder cancer.

  16. ADAM28 showed significant differences compared with normal individuals, so it may be a biomarker of bladder cancer.

  17. ADAM28 might actively participate in manipulating the proliferation, differentiation, and apoptosis of human dental pulp stem cells (HDPSCs).

  18. It plays a role in cancer cell proliferation, invasion and metastasis. (review)

  19. These data provide the first evidence that CTGF is a novel substrate of ADAM28 and suggest that ADAM28 may promote VEGF(165)-induced angiogenesis in the breast carcinomas by the CTGF digestion in the CTGF/VEGF(165) complex.

  20. High ADAM28 in serum is associated with non-small-cell lung cancers.

ADAM28 Antigen Profile

Protein Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform.

Gene names and symbols associated with ADAM28

  • ADAM metallopeptidase domain 28 (Adam28) antibody
  • a disintegrin and metallopeptidase domain 28 (Adam28) antibody
  • ADAM metallopeptidase domain 28 (ADAM28) antibody
  • ADAM23 antibody
  • ADAM 28 antibody
  • C130072N01Rik antibody
  • D430033C21Rik antibody
  • Dtgn1 antibody
  • eMDCII antibody
  • eMDC II antibody
  • MDC-L antibody
  • MDC-Lm antibody
  • MDC-Ls antibody
  • MDCL antibody
  • TECADAM antibody

Protein level used designations for ADAM28

a disintegrin and metallopeptidase domain 28 , a disintegrin and metalloprotease domain 28 , a disintegrin and metalloproteinase domain 28 , disintegrin and metalloproteinase domain-containing protein 28 , ADAM 28 , disintegrin 1 , metalloproteinase-disintegrin domain containing protein TECADAM , thymic epithelial cell-ADAM , epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II , epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II , metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L

GENE ID SPECIES
290344 Rattus norvegicus
13522 Mus musculus
10863 Homo sapiens
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