ADAM28 antibody (AA 321-420)

Catalog No. ABIN758861

There is 1 publication for this product available. The Rabbit Polyclonal anti-ADAM28 antibody is suitable to detect ADAM28 in samples from Human. It has been validated for FACS, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for ADAM28 antibody (AA 321-420) (ABIN758861)

Target: ADAM28 (ADAM Metallopeptidase Domain 28 (ADAM28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM28 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ADAM28 Antibody

Binding Specificity: AA 321-420

Purpose: ADAM28 Polyclonal Antibody

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADAM28

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ADAM28 antibody (ABIN758861)

Zhang, Zhu, Xiao, Liu, Han, Chen, Hou, Shen, Li, Ma, Wang: "CD19 regulates ADAM28-mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells." in: Journal of cellular and molecular medicine, Vol. 21, Issue 12, pp. 3658-3669, (2017) (PubMed).

Target Details for ADAM28

Target: ADAM28 (ADAM Metallopeptidase Domain 28 (ADAM28))

Alternative Name: ADAM28

Background:

Synonyms: MDCL, MDC-L, eMDCII, ADAM 28, eMDC II, Disintegrin and metalloproteinase domain-containing protein 28, Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L, ADAM28, ADAM23

Background: May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.

Gene ID: 10863

UniProt: Q9UKQ2