anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) Antibodies

ADAMTS1 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Additionally we are shipping ADAMTS1 Kits (32) and ADAMTS1 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAMTS1 79252  
ADAMTS1 9510 Q9UHI8
ADAMTS1 11504 P97857
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Top anti-ADAMTS1 Antibodies at antibodies-online.com

Showing 10 out of 134 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, FACS, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using ADAMTS1 mAb against human ADAMTS1 (AA: 858-960) recombinant protein. (Expected MW is 38.3 kDa) 0.1 mg Log in to see 8 to 11 Days
$577.50
Details
Human Mouse Un-conjugated ELISA, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using ADAMTS1 mAb against human ADAMTS1 (AA: 858-960) recombinant protein. (Expected MW is 38.3 kDa) 0.1 mg Log in to see 8 to 11 Days
$577.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of ADAMTS1 expression in A549 (A), SW480 (B), HeLa (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of ADAMTS1 expression in rat cardiac muscle extract ( Lane 1), and mouse brain extract ( Lane 2). ADAMTS1 at 105KD was detected using rabbit anti- ADAMTS1 Antigen Affinity purified polyclonal antibody (Catalog #) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot (WB) analysis of specific cells using ADAMTS-1 Polyclonal Antibody. 100 μL Log in to see Available
$363.46
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Testis, Vessels (formalin-fixed, paraffin-embedded) stained with ADAMTS1 antibody ABIN292613 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ADAMTS1 antibody IHC of human testis, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Testis, Vessels (formalin-fixed, paraffin-embedded) stained with ADAMTS1 antibody ABIN290128 at 13 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ADAMTS1 antibody IHC of human testis, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Horse Rabbit Un-conjugated IHC, IHC (p) Human Testis, Vessels (formalin-fixed, paraffin-embedded) stained with ADAMTS1 antibody ABIN625844 at 1.3 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ADAMTS1 antibody IHC of human testis, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Testis, Vessels (formalin-fixed, paraffin-embedded) stained with ADAMTS1 antibody ABIN625843 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ADAMTS1 antibody IHC of human testis, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis of ADAMTS1 using K562 whole cell lysates ABIN6279082 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-ADAMTS1 Antibodies

  1. Human Polyclonal ADAMTS1 Primary Antibody for IHC (p) - ABIN5555479 : McRae, Forgan, McNeill, Addinsall, McCulloch, Van der Poel, Stupka: Glucocorticoids Improve Myogenic Differentiation In Vitro by Suppressing the Synthesis of Versican, a Transitional Matrix Protein Overexpressed in Dystrophic Skeletal Muscles. in International journal of molecular sciences 2018 (PubMed)

  2. Human Polyclonal ADAMTS1 Primary Antibody for IHC (p) - ABIN4278260 : Pascal, Ai, Masoodi, Wang, Wang, Eisermann, Rigatti, OMalley, Ma, Wang, Dar, Parwani, Simons, Ittman, Li, Davies, Wang: Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice. in PLoS ONE 2013 (PubMed)

More Antibodies against ADAMTS1 Interaction Partners

Pig (Porcine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. Expression and induction of ADAMTS-1 through receptor-mediated action of progesterone in cumulus cells is one of essential requirements for gonadotropin-regulated cumulus expansion of porcine cumulus-oocyte complexes.

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. study indicates that disintegrin and metalloproteinase with thrombospondin motifs 1(ADAMTS1) participates in bovine endometrial remodeling

  2. Data indicate that ADAMTS1 promoter activity and mRNA expression were increased by forskolin and human chorionic gonadotropin.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. expressed 2.56-fold less in Sertoli cells in nonobstructive azoospermia than in obstructive azoospermia; insufficient expression in Sertoli cells may have an important role in the etiology of male infertility

  2. Increased levels of ADAMTS-1 could be a potential marker for the etiopathogenesis of PCOS in adolescents and younger-aged females and predict the development of CVD [cardiovascular disease ] risk and IR among all patients with the same age.

  3. ADAMTS 1, 4, 12, and 13 levels in the maternal and cord blood were lower in the preeclampsia group than in the control group. ADAMTS 1, 4, and 12 levels in placental tissues were higher in the preeclampsia group.

  4. we identified Adamts1 as the modulator of a potent pathway that converts changes in diet into a cellular signal in adipose tissue that controls APC activity in vivo

  5. ADAMTS 1 may be necessary during the decidualization and implantation stages of early normal pregnancy.

  6. Significant differences in gene expression profiles were observed between patients with post-kidney transplant bladder tumors and those with conventional bladder tumors. ADAMTS1 expression was significantly lower in first group than in the second.

  7. Our study demonstrated that altered levels of ADAMTS-1 and aggrecan may have a partial role in the etiopathogenesis of Polycystic ovary syndrome (PCOS), and ADAMTS-1 could be a predictive marker for implantation success in PCOS patients.

  8. Adamts1 acts as an extracellular matrix 'modifier', with miR-181d-induced downregulation, that regulates adipocyte lineage commitment and obesity.

  9. This study showed that ADAMTS1, 8, and 18 are highly expressed in GC and its nodal metastases, suggesting important roles of these proteases in carcinogenesis and lymphatic metastasis. The findings from the present study indicate that these proteases may be promising candidates for novel and alternative treatments in GC (gastric cancer)

  10. Taken together, our findings suggested that miR-362-3p inhibits the proliferation and migration of VSMCs by directly targeting ADAMTS1, which might provide novel insight into the molecular mechanisms underlying the action of miR-362-3p in atherosclerosis.

  11. ADAMTS1 has diverse roles in angiogenesis, tumor microenvironment and lymphangiogenesis.

  12. Patients with Marfan syndrome showed elevated NOS2 and decreased ADAMTS1 protein levels in the aorta.

  13. Data indicate that serum versican levels were significantly decreased in polycystic ovary syndrome (PCOS) patients, and that serum ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin motif-1) and versican levels were significantly and positively correlated with each other.

  14. Findings indicate that ADAMTS-1 has proteolytic functions in the nucleus through its interaction with aggrecan substrate in normal and tumoral breast cells.

  15. implicated in knee destruction in Kashin-Beck disease

  16. All ADAMTS tested in our study were expressed in both stable and unstable carotid plaques, especially in smooth muscle cells and macrophages. Analysis of the expression pattern on mRNA level showed significant higher expression of ADAMTS1 in unstable plaques compared with stable plaques.

  17. ADAMTS1 protein levels in semen were significantly lower in males with infertility. Sperm count and motility showed a negative correlation with levels of ADAMTS1 protein expression.

  18. increased expression of ADAMTS1 protein in macrophages and neutrophils that infiltrated aortic tissues may promote the progression of acute aortic dissection

  19. High ADAMTS1 expression was significantly associated with tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells.

  20. progesterone acts via the progesterone receptor to modulate ADAMTS 1 and 4 levels in ovarian cancer cell lines.

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. The developmental arrest of early secondary follicles following furin disruption might be rooted in the loss of the mature form of ADAMTS1 and compromised proliferation of granulosa cells in mutant mice.

  2. Data show that NOTCH1 is a target of ADAMTS1 metalloproteinase activity, which reduces Notch signaling, leading to increased satellite cell activation.

  3. Reduced tumors in ADAMTS1 knockout mice displayed a paradoxical increase in vascular density and vascular-related genes; a detailed characterization revealed an impaired vasculature, along with a minor infiltration of macrophages. melanoma xenografts showed a relevant induction of its expression in stroma compartments.

  4. Adamts1 acts as an extracellular matrix 'modifier', with miR-181d-induced downregulation, that regulates adipocyte lineage commitment and obesity.

  5. Genetic haploinsufficiency of Adamts1 in mice causes thoracic aortic aneurysms and dissections similar to Marfan syndrome.

  6. An ADAMTS1 blocking antibody suppressed the SPARC-induced collagen I secretion, indicating that SPARC promoted collagen production directly through ADAMTS1 interaction. In conclusion, ADAMTS1 is an important mediator of SPARC-regulated cardiac aging.

  7. increased expression of ADAMTS1 protein in macrophages and neutrophils that infiltrated aortic tissues may promote the progression of acute aortic dissection

  8. The resilience of casp1(-/-) mice to SIRS lethality is associated with a lower inflammatory response, loss of hippocampal gene coexpression patterns, and increased hippocampal Adamts1 gene expression.

  9. Adamts-1 upregulation by inducers of pathological vascular remodeling is mediated by specific signal transduction pathways involving NFAT or C/EBPbeta transcription factors.

  10. Western blot analyses indicated that aggrecanase-generated proteoglycan fragments are produced after SCI.

  11. Adamts1 potentially contributes to the increased serum levels of CTX in rickets/osteomalacia.

  12. The present study suggests a functional coupling between the GABAergic system and the transcriptional regulation of the two genes (Btg2 and Adamsts1) in the hippocampus of adult mice.

  13. ADAMTS1 is associated with regulating neural plasticity.

  14. These results reveal that Adamts1 has an impact on bone mineral density and thus further confirm Adamts1 as a potent regulator of bone remodeling.

  15. fibulin-1 regulates versican-dependent events in ventricular morphogenesis by promoting ADAMTS1 cleavage of versican leading to suppression of trabecular cardiomyocyte proliferation mediated by the ErbB2-Map kinase pathway.

  16. Pericyte-derived TIMP3 stabilized and ADAMTS1 destabilized the capillary tubular networks

  17. results indicate that up-regulation of ADAMTS1 in hepatic stellate cells constitutes a new mechanism for control of TGF-beta activation in chronic liver disease.

  18. Data demonstrate that Adamts1 and Adamts4 play redundant and essential roles in perinatal kidney development.

  19. ADAMTS-1 is implicated as having a proangiogenic role.

  20. AHR, a novel acute hypoxia-response sequence, drives reporter gene expression under hypoxia in vitro and in vivo.

Xenopus laevis ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. ADAMTS1 negatively modulates FGF signaling in the Xenopus embryo.

ADAMTS1 Antigen Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Gene names and symbols associated with ADAMTS1

  • ADAM metallopeptidase with thrombospondin type 1 motif 1 (ADAMTS1) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif 1 (adamts1) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (Adamts1) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (adamts1) antibody
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif 1 L homeolog (adamts1.L) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif 1 (Adamts1) antibody
  • ADAM-TS1 antibody
  • ADAMTS antibody
  • ADAMTS-1 antibody
  • adamts1 antibody
  • C3-C5 antibody
  • METH-1 antibody
  • METH1 antibody
  • xadamts1 antibody

Protein level used designations for ADAMTS1

metalloproteinase with thrombospondin-like motifs-1 , ADAM metallopeptidase with thrombospondin type 1 motif, 1 , A disintegrin and metalloproteinase with thrombospondin motifs 1 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 , ADAM-TS 1 , ADAM-TS1 , ADAMTS-1 , a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1) , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 , a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1 , METH-1 , human metalloproteinase with thrombospondin type 1 motifs , ADAM metallopeptidase with thrombospondin type 1 motif 1 L homeolog

GENE ID SPECIES
791251 Equus caballus
100151734 Xenopus (Silurana) tropicalis
418479 Gallus gallus
497061 Sus scrofa
79252 Rattus norvegicus
512171 Bos taurus
565145 Danio rerio
9510 Homo sapiens
11504 Mus musculus
100548786 Meleagris gallopavo
100415773 Ovis aries
100173562 Pongo abelii
100686153 Canis lupus familiaris
495679 Xenopus laevis
100725727 Cavia porcellus
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