anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) Antibodies

ADAMTS13 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Additionally we are shipping ADAMTS13 Kits (38) and ADAMTS13 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAMTS13 11093 Q76LX8
ADAMTS13 279028 Q769J6
ADAMTS13 102554393  
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Top anti-ADAMTS13 Antibodies at antibodies-online.com

Showing 10 out of 99 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB <strong>Immunohistochemistry:</strong> ADAMTS13 antibody staining of Formalin-Fixed Paraffin-Embedded Human hepatocarcinoma followed by peroxidase-conjugation to the secondary antibody and DAB staining. <strong>Western blot analysis:</strong> ADAMTS13 antibody staining of CEM cell line lysates (35 µg/lane). ADAMTS13 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Detection of Recombinant Human Adam-TS13 by Western Blot. Samples: Purified recombinant Adam-TS13. Antibody: ABIN152016 used at the indicated concentrations. Detection: Chemiluminescence with an exposure time of approximately 30 seconds. Western Blot: ADAMTS13 Antibody - Purified recombinant Adam-TS13. Antibody used at the indicated concentrations. 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ADAMTS13 Antibody (Center)(ABIN391641) in CEM cell line lysates (35 µg/lane). ADAMTS13 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADAMTS13 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated IP, WB 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Goat Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated CyTOF, FACS, IP, WB Detection of ADAMTS13 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human ADAMTS13 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 8 to 9 Days
$297.85
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ADAMTS13 Antibody in CEM cell line lysates (35ug/lane) Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADAMTS13 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Used in DAB staining on fromalin fixed paraffin- embedded liver tissue 100 μg Log in to see 13 to 16 Days
$240.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ADAMTS13 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

ADAMTS13 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ADAMTS13 Antibodies

  1. Human Polyclonal ADAMTS13 Primary Antibody for WB - ABIN152016 : Tao, Wang, Choi, Bernardo, Nishio, Sadler, López, Dong: Cleavage of ultralarge multimers of von Willebrand factor by C-terminal-truncated mutants of ADAMTS-13 under flow. in Blood 2005 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal ADAMTS13 Primary Antibody for IP, WB - ABIN251718 : Feng, Eyler, Zhang, Maga, Nester, Kroll, Smith, Afshar-Kharghan: Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome. in Blood 2013 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal ADAMTS13 Primary Antibody for WB - ABIN251717 : Turner, Nolasco, Ruggeri, Moake: Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage. in Blood 2009 (PubMed)

More Antibodies against ADAMTS13 Interaction Partners

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. Missense variant in ADAMTS13 gene in a patient with NCIPH decreases secretion and activity of ADAMTS13 protein.

  2. Deficiency of the von Willebrand factor-cleaving protease ADAMTS13 is central to the pathophysiology of thrombotic thrombocytopenic purpura. Reviewed is the evidence emerged from epidemiological studies of an inverse relationship between the plasma levels of ADAMTS13 and the risk of acute coronary syndrome. [review]

  3. Data indicate that in cultured endothelial cells, one role of endogenous ADAMTS-13 is regulation of angiogenesis, mediated through VEGF (show VEGFA Antibodies) and AKT (show AKT1 Antibodies) signaling pathway.

  4. ADAMTS13 haplotype had an independent protective effect on CAD (show CAD Antibodies) and genetic variation of vWF (show VWF Antibodies) V1565L polymorphism modulates ADAMTS13 activity.

  5. The relative deficiency of plasma ADAMTS13 activity in subarachnoid haemorrhage patients may associate with worse outcome.

  6. Low ADAMTS13 was associated with increased mortality in patients with severe sepsis and septic shock and was comparable to APACHE II scores for predicting mortality.

  7. These observations support the hypothesis that a significantly reduced ADAMTS13/VWF (show VWF Antibodies) ratio in the coronary artery flow plays a pathogenic role in acute coronary syndromes (ACS (show PLA2G15 Antibodies)) and suggest that transition from laminar to turbulent flow at sites of coronary stenosis further enhances VWF (show VWF Antibodies) activation and deposition.

  8. Low ADAMTS-13 activity is associated with an increased risk of coronary heart disease in the elderly, independently of VWF (show VWF Antibodies) and established cardiovascular risk factors

  9. As folding stability was progressively disrupted, proteolysis by ADAMTS13 increased. Due to the range of folding stabilities and wide distribution of VWF (show VWF Antibodies) A2 domain mutations studied, we conclude that these mutations disrupt regulated folding of the VWF (show VWF Antibodies) A2 domain

  10. The 'closed' conformation of ADAMTS-13 restricts its specificity and protects against fibrinogenolysis

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. Adamts13 deficiency in obese mice promotes hepatic microthrombosis.

  2. results suggest that ADAMTS13 controls key steps of ischemic vascular remodeling and that recombinant ADAMTS13 is a putative therapeutic avenue for promoting stroke recovery.

  3. ADAMTS13 retards progression of diabetic nephropathy, most likely by inhibiting VWF (show VWF Antibodies)-dependent intrarenal thrombosis.

  4. administration of ADAMTS13 5 minutes after occlusion dose-dependently dissolved these t-PA (show PLAT Antibodies)-resistant thrombi resulting in fast restoration of MCA (show RSPH1 Antibodies) patency and consequently reduced cerebral infarct sizes

  5. Sleeping beauty transposon-mediated gene therapy achieved sustained expression of transgene ADAMTS13 and long-term prophylaxis against congenital thrombotic thrombocytopenic purpura in Adamts13(-/-) mice.

  6. Results also suggest that Toxoplasma gondii-mediated apoptosis might play a pivotal role and a different type of role in the mechanism of neurodegeneration and neuropathology in the process of toxoplasma encephalitis. Furthermore, expression of ADAMTS-13 might give an idea of the progress and is critical for diagnosis of this disease.

  7. Letter: deficiency of ADAMTS13 results in increased formation of venous thrombosis in mice.

  8. ADAMTS13 substrate specificity

  9. Data indicate that the p.D187H mutation impairs ADAMTS13 activity and secretion and may contribute to thrombotic thrombocytopenic purpura.

  10. Data show that metalloendopeptidase (show THOP1 Antibodies) ADAMTS13 does not directly promote development of adipose tissue.

ADAMTS13 Antigen Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Gene names and symbols associated with ADAMTS13

  • ADAM metallopeptidase with thrombospondin type 1 motif 13 (ADAMTS13) antibody
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif 13 (Adamts13) antibody
  • ADAM-TS13 antibody
  • ADAMTS-13 antibody
  • ADAMTS13 antibody
  • C9orf8 antibody
  • Gm710 antibody
  • vWF-CP antibody
  • VWFCP antibody

Protein level used designations for ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif, 13 , A disintegrin and metalloproteinase with thrombospondin motifs 13 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , vWF-cleaving protease , von Willebrand factor-cleaving protease , ADAM-TS 13 , ADAM-TS13 , ADAMTS-13 , ADAMTS13 isoform IAP-b , vWF-CP mRNA for von Willebrand factor-cleaving , ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like , A disintegrin and metalloproteinase with thrombospondin motifs 13-like , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

GENE ID SPECIES
100069281 Equus caballus
11093 Homo sapiens
279028 Mus musculus
532272 Bos taurus
100320289 Danio rerio
100404947 Callithrix jacchus
100343027 Oryctolagus cuniculus
100481099 Ailuropoda melanoleuca
100226372 Taeniopygia guttata
100630922 Canis lupus familiaris
102554393 Rattus norvegicus
100727045 Cavia porcellus
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