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anti-ADP Ribosylation Factor Like GTPase 6 (ARL6) Antibodies

The protein encoded by ARL6 belongs to the ARF family of GTP-binding proteins. Additionally we are shipping ADP Ribosylation Factor Like GTPase 6 Kits (13) and ADP Ribosylation Factor Like GTPase 6 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ARL6 84100 Q9H0F7
ARL6 56297 O88848
ARL6 363760  
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Top anti-ADP Ribosylation Factor Like GTPase 6 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, IHC   100 μg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using ARL6 antibody. Immunohistochemistry of paraffin-embedded human prostate using ARL6 antibody at dilution of 1:100 (x40 lens). 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with ARL6 antibody ABIN305749 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ARL6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, WB ABIN6273201 at 1/100 staining Human lymph cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of HEK-293T cells, using BBS3 antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg 6 to 8 Days
$495.00
Details
Mouse Goat Un-conjugated ELISA, WB   0.1 mg 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of ARL6 staining in human prostate formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of ARL6 expression in HEK293T (A), mouse kidney (B), mouse brain (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney shows strong cytoplasmic positivity in tubuli. Western Blot analysis of (1) Negative control (vector only transfected HEK293T lysate), and (2) Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). 100 μL 11 to 12 Days
$637.32
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using ARL6 antibody. Immunohistochemistry of paraffin-embedded human prostate using ARL6 antibody. 100 μL 13 to 14 Days
$393.25
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.05 mg 2 to 3 Days
$618.75
Details

Top referenced anti-ADP Ribosylation Factor Like GTPase 6 Antibodies

  1. Human Polyclonal ARL6 Primary Antibody for IHC - ABIN965594 : Chiang, Nishimura, Searby, Elbedour, Carmi, Ferguson, Secrist, Braun, Casavant, Stone, Sheffield: Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3). in American journal of human genetics 2004 (PubMed)
    Show all 4 Pubmed References

More Antibodies against ADP Ribosylation Factor Like GTPase 6 Interaction Partners

Human ADP Ribosylation Factor Like GTPase 6 (ARL6) interaction partners

  1. In the 64 BBS patients (44 males, 20 females) were studied, mutations were predominant in BBS10 and ARL6 genes; the c.272T>C; p.(I91T) mutation in ARL6 gene was a recurrent mutation

  2. Mutations of the ARL6 gene cause Bardet-Biedl syndrome, a heterogeneous disorder that increases the risk of Hypertension and Diabetes mellitus.

  3. Elevated levels of serum ARL6 were able to discriminate between excessive alcohol users and controls.

  4. Results show that BBS1 and BBS3 regulates the ciliary traficking of PC1.

  5. The BBSome is a coat-like ciliary trafficking complex composed of proteins mutated in Bardet-Biedl syndrome. ARL6 E108A mutation prevents BBSome recruitment to cilia.

  6. Arl6 is indispensable in cilia signaling but dispensable in ciliogenesis (Review).

  7. Mutations identified in the present study extend the body of evidence implicating the genes ARL6 and BBS10 in causing Bardet-Biedl syndrome.

  8. BBS3 A89V is sufficient to rescue the transport delays induced by the loss of BBS3 but was unable to rescue vision impairment

  9. Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling.

  10. the first null mutation reported in BBS3 gene in patient with Bardet-Biedl syndrome

  11. These data demonstrate that the BBS3L transcript is required for proper retinal function and organization.

  12. We uncovered four different homozygous substitutions in ARL6 in four unrelated families affected with Bardet-Biedl syndrome, two of which disrupt a threonine residue important for GTP binding and function of several related small GTP-binding proteins.

  13. These findings implicate that Arl6 mutants are destabilized and eliminated by the proteasome in cells, probably due to the altered nucleotide-binding properties.

Mouse (Murine) ADP Ribosylation Factor Like GTPase 6 (ARL6) interaction partners

  1. Results show that BBS1 and BBS3 regulates the ciliary traficking of PC1.

  2. IFT27 prevents aggregation of nucleotide-free ARL6 in solution

  3. Bbs3 knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes

  4. These data demonstrate that the BBS3L transcript is required for proper retinal function and organization.

  5. ARL6 was expressed in the neural plate and probably in the somites

Zebrafish ADP Ribosylation Factor Like GTPase 6 (ARL6) interaction partners

  1. Loss-of-function of bbs1 or bbs3 in zebrafish results in the same phenotypes as knockdown of other Bardet-Biedl syndrome genes.[bbs3]

  2. These data demonstrate that the BBS3L transcript is required for proper retinal function and organization.

ADP Ribosylation Factor Like GTPase 6 (ARL6) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.

Gene names and symbols associated with ARL6

  • ADP ribosylation factor like GTPase 6 (ARL6) antibody
  • ADP-ribosylation factor-like 6 (Arl6) antibody
  • ADP-ribosylation factor like GTPase 6 (Arl6) antibody
  • ADP-ribosylation factor-like 6 (arl6) antibody
  • ADP-ribosylation factor-like protein 6 (arl-6) antibody
  • ADP ribosylation factor like GTPase 6 L homeolog (arl6.L) antibody
  • 1110018H24Rik antibody
  • 2210411E14Rik antibody
  • arl6 antibody
  • BBS3 antibody
  • RP55 antibody
  • zgc:101762 antibody

Protein level used designations for ARL6

ADP-ribosylation factor-like protein 6 , Bardet-Biedl syndrome 3 protein , ADP-ribosylation-like 6 , ADP-ribosylation-like factor homolog ARL6 , bbs3 , ADP ribosylation factor like GTPase 6 L homeolog , ADP-ribosylation factor-like 6

GENE ID SPECIES
84100 Homo sapiens
519014 Bos taurus
56297 Mus musculus
363760 Rattus norvegicus
494134 Danio rerio
183311 Caenorhabditis elegans
447355 Xenopus laevis
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