anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) Antibodies

This locus encodes an AT-rich DNA interacting domain-containing protein. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ARID1B 239985  
ARID1B 282546  
ARID1B 57492 Q8NFD5
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Top anti-ARID1B Antibodies at

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of BAF250B staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of BAF250B staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from LOVO cells, using BAF250B Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using BAF250B Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to ARID1B on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to ARID1B on HeLa cell. [antibody concentration 10 ug/ml] 100 μg 11 to 12 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Available
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6274434 staining LOVO cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis of extracts from LOVO cells, using BAF250B antibody. 100 μL 11 to 12 Days
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB 100 μg 11 to 14 Days
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti-ARID1B Polyclonal Antibody, Unconjugated (ABIN1714038) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 14 to 21 Days
Human Rabbit Un-conjugated ELISA, IF, IHC (p), WB 200 μL 12 to 14 Days
Human Rabbit Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.78 KDa) . 50 μL 11 to 12 Days

Top referenced anti-ARID1B Antibodies

  1. Human Monoclonal ARID1B Primary Antibody for IF, IHC (p) - ABIN566118 : Coatham, Li, Karnezis, Hoang, Tessier-Cloutier, Meng, Soslow, Blake Gilks, Huntsman, Stewart, Postovit, Köbel, Lee: Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ARID1B Primary Antibody for IF, IHC (p) - ABIN528194 : Flores-Alcantar, Gonzalez-Sandoval, Escalante-Alcalde, Lomelí: Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle. in Cell and tissue research 2011 (PubMed)

  3. Human Polyclonal ARID1B Primary Antibody for IHC, IP - ABIN252822 : Sim, White, Fitzpatrick, Wilson, Gillies, Pope, Mountford, Torring, McKee, Vulto-van Silfhout, Jhangiani, Muzny, Leventer, Delatycki, Amor, Lockhart: Expanding the phenotypic spectrum of ARID1B-mediated disorders and identification of altered cell-cycle dynamics due to ARID1B haploinsufficiency. in Orphanet journal of rare diseases 2014 (PubMed)

More Antibodies against ARID1B Interaction Partners

Mouse (Murine) AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) interaction partners

  1. Genome-wide gene expression patterns in Arid1b hKO mice were similar to those in Autism spectrum disorder (ASD)patients and Chd8-haploinsufficient mice, an ASD model, and to developmental changes in gene expression in fast-spiking cells in the mouse brain. Our results suggest that Arid1b haploinsufficiency causes ASD-like phenotypes in mice.

  2. In the brain, Arid1b haploinsufficiency resulted in changes in the expression of SWI/SNF-regulated genes implicated in neuropsychiatric disorders.

  3. STAT3/Arid1b/beta-catenin pathway is driving neurofibroma initiation.

  4. The patterns of expression of ARID1A and ARID1B genes through various mouse embryonic stages, was examined.

  5. These data suggest that the BAF250B-associated SWI/SNF is essential for mouse embryonic stem cells to maintain their normal proliferation and pluripotency.

  6. A subset of mammalian SWI/SNF complexes, specifically containing ARID1B, is required for efficient cell cycle re-entry and for association of activation factors with the c-myc promoter.

Human AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) interaction partners

  1. Study has highlighted that miR-486-3p expression is increased in serum of patients with autism and supports that miR-486-3p inhibits the expression of ARID1B.

  2. We report on a 4-year-old male child who was found to be heterozygous for ARID1B de novo pathogenic NM_020732.3:c.3323_3324delAA; p.(Lys1108Argfs) mutation. The coding region (+/-5 bp) of the SWI/SNF complex genes showed a de novo heterozygous sequence change in the ARID1B gene: NM_020732.3:c.3323_3324delAA; p.(Lys1108Argfs). The variant was confirmed by Sanger sequencing and was not detected in the parental samples.

  3. the correlation between the loss of ARID1A immunoreactivity and reduced ARID1B levels indicates that ARID1B could be an attractive target for anti-cancer therapy.

  4. findings establish mutations in ARID1B as the underlying genetic defect in the HHID syndrome in two of three patients.

  5. The authors find that ARID1A has a dominant role in maintaining chromatin accessibility at enhancers, while the contribution of ARID1B is evident only in the context of ARID1A mutation.

  6. we identified a subgroup of neuroblastoma with ARID1B mutation shows an aggressive behavior. These findings may provide a new biomarker to identify another subgroup of neuroblastoma with high-risk features.

  7. these results highlighted the significant genetic contribution of the ARID1B variant, rs73013281, to susceptibility for HCC, especially in interaction with physical activity.

  8. we identified concurrent ARID1A and ARID1B inactivating mutations with consequent loss of protein expression in the undifferentiated component of approximately one-quarter of dedifferentiated endometrial and ovarian carcinomas

  9. Of the 34 undifferentiated endometrial carcinomas examined, 17 (50%) exhibited SWI/SNF complex inactivation, with 11 tumors showing complete loss of both ARID1A and ARID1B, 5 showing complete loss of BRG1 and 1 showing complete loss of INI1. Ten of the remaining 17 undifferentiated carcinomas showed the following alterations: 5 tumors (15%) showed loss of ARID1A only with intact ARID1B, BRG1, and INI1 expression.

  10. We report here the clinical, genetic, and proteomic phenotypes of an individual with a unique apparent de novo mutation of ARID1B due to an intragenic duplication

  11. HSCR was observed in a patient with a truncating mutation in ARID1B, further expanding the phenotypic spectrum of Coffin-Siris syndrome. This suggests that the BAF complex does not only play a role in the enteric system of Drosophila, but also in humans.

  12. Case Report: Melanotic Xp11 renal cell carcinoma with ARID1B-TFE3 gene fusion.

  13. The clinical features of both patients are felt to be consistent with an ARID1B-related disorder. To our knowledge, this is the first report of a pathogenic mutation in ARID1B being passed from an affected parent to their offspring.

  14. We report two teenagers with ID whose molecular diagnosis of a SMARC2A or ARID1B mutation, respectively, was established through clinical exome analysis.

  15. The ARID1B gene, commonly mutated in multiple types of cancer, was identified as an additional ZNF384 gene fusion partner.

  16. knockdown of the SWI/SNF component ARID1B prevents OIS and cooperates with RAS to induce liver tumors

  17. Chromosome analysis by array-CGH revealed a small interstitial 6q deletion spanning approximately 1.1 Mb of DNA and containing only one coding gene, ARID1B. We suggest that ARID1B is the key gene behind 6q microdeletion syndrome, and we discuss its possible role in the phenotypic manifestations

  18. Gonadal mosaicism in ARID1B gene causes intellectual disability and dysmorphic features in three siblings.

  19. ARID1B potentially serves as a valuable prognostic and predictive biomarker as well as a therapeutic target in breast cancer.

  20. This study demonstrate that ARID1B is required for neuronal differentiation in the developing brain, such as in dendritic arborization and synapse formation.

ARID1B Antigen Profile

Protein Summary

This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with ARID1B

  • AT rich interactive domain 1B (SWI1-like) (arid1b) antibody
  • AT rich interactive domain 1B (SWI-like) (Arid1b) antibody
  • AT-rich interaction domain 1B (Arid1b) antibody
  • AT-rich interaction domain 1B (ARID1B) antibody
  • 6A3-5 antibody
  • 8030481M12 antibody
  • 9330189K18Rik antibody
  • AI836955 antibody
  • Ardi1b antibody
  • B230217J03Rik antibody
  • BAF250B antibody
  • BRIGHT antibody
  • DAN15 antibody
  • ELD/OSA1 antibody
  • fd07d11 antibody
  • mKIAA1235 antibody
  • MRD12 antibody
  • OSA2 antibody
  • P250R antibody
  • si:dkey-60a16.3 antibody
  • smcf-1 antibody
  • Smcf1 antibody
  • wu:fd07d11 antibody

Protein level used designations for ARID1B

AT rich interactive domain 1B (Swi1 like) , AT-rich interactive domain-containing protein 1B , transcription factor 1 , ARID domain-containing protein 1B , BRG1-associated factor 250b , BRG1-binding protein ELD/OSA1 , ELD (eyelid)/OSA protein

569589 Danio rerio
239985 Mus musculus
282546 Rattus norvegicus
57492 Homo sapiens
421650 Gallus gallus
484047 Canis lupus familiaris
505229 Bos taurus
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