ARID1B antibody (AA 1371-1420)

Catalog No. ABIN1534011

This Rabbit Polyclonal antibody specifically detects ARID1B in WB, IF, IHC and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for ARID1B antibody (AA 1371-1420) (ABIN1534011)

Target: ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID1B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Product Details anti-ARID1B Antibody

Binding Specificity: AA 1371-1420

Purpose: BAF250b Antibody

Specificity: BAF250b Polyclonal Antibody detects endogenous levels of BAF250b protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BAF250B. AA range:1371-1420

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ARID1B

Target: ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))

Alternative Name: BAF250B

Background:

Synonyms: ARID1B, BAF250B, DAN15, KIAA1235, OSA2, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, BRG1-associated factor 250b, BAF250B, BRG1-binding protein hELD/OSA1, Osa homolog 2, hOsa2, p250R

Background: This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2012],

Gene Name: ARID1B

Protein Name: AT-rich interactive domain-containing protein 1B

Molecular Weight: 236 kDa

Gene ID: 57492

UniProt: Q8NFD5