Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by ARID4A is a ubiquitously expressed nuclear protein. Additionally we are shipping and many more products for this protein.
Showing 10 out of 16 products:
Cow (Bovine) Polyclonal ARID4A Primary Antibody for WB - ABIN2777742
Meehan, Samant, Hopper, Carrozza, Shevde, Workman, Eckert, Verderame, Welch: Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription. in The Journal of biological chemistry 2004
Show all 2 Pubmed References
Consistently, our ITC assays also showed that DNA does not significantly enhance the histone binding ability of the chromo barrel domain of RBBP1.
The RBBP1 Tudor domain binds both double- and single-stranded DNA with an affinity of 10-100 muM; no apparent DNA sequence specificity was detected.
ARID4a (AT-rich interacting domain 4a, also known as RBP1) and CCL5 (C-C motif ligand 5) are targets for miR-302.
chromobarrel domain of RBBP1 is responsible for recognizing methylated histone tails in chromatin remodeling and epigenetic regulation
RBP1 and the mSin3 histone deacetylase complex bind to BRMS1 and repress transcription
there is an E2-dependent, ER isoform-specific transcriptional activation of the RBBP1 gene, which in part, is explained by the differential activity of ER AF1 and enhancer element binding
Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells.
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
AT-rich interactive domain-containing protein 4A
, AT rich interactive domain 4A (RBP1-like)
, retinoblastoma-binding protein 1
, at rich interactive domain 4a (rbp1 like)
, AT-rich interactive domain-containing protein 4A-like
, ARID domain-containing protein 4A
, retinoblastoma binding protein 1
, AT rich interactive domain 4A (Rbp1 like)