ARID4A antibody

Catalog No. ABIN931104

The Mouse Monoclonal anti-ARID4A antibody (Clone 112C4a) (ABIN931104) specifically detects ARID4A in DB. The antibody is reactive with Human samples.

Quick Overview for ARID4A antibody (ABIN931104)

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ARID4A antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 112C4a

Product Details anti-ARID4A Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: ARID4 A antibody was raised in mouse using recombinant Human At Rich Interactive Domain 4 (Rbp1-Like) (Arid4 )

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: ARID4 A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for ARID4A

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Alternative Name: ARID4A

Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. Synonyms: Monoclonal ARID4A antibody, Anti-ARID4A antibody, AT rich interactive domain 4A antibody, RBP1 antibody, RBBP1 antibody, RBP-1 antibody.