anti-Acetyl-CoA Acetyltransferase 1 (ACAT1) Antibodies

The protein encoded by ACAT1 belongs to the acyltransferase family. Additionally we are shipping ACAT1 Kits (20) and ACAT1 Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACAT1 38 P24752
ACAT1 25014 P17764
ACAT1 110446 Q8QZT1
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Top anti-ACAT1 Antibodies at antibodies-online.com

Showing 10 out of 188 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: ACAT1 Antibody [NBP1-89284] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Western Blot: ACAT1 Antibody [NBP1-89284] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample(30 μg of whole cell lysate) A:293T B:A431, C:MOLT4, 10% SDS PAGE antibody diluted at 1:500 ICC/IF Image ACAT1 antibody [N1N3] detects ACAT1 protein at mitochondria by immunofluorescent analysis. Sample: A431 cells were fixed in 2% paraformaldehyde/culture medium at 37℃ for 30 min. Green: ACAT1 protein stained by ACAT1 antibody [N1N3] , diluted at 1:500. Blue: Hoechst 33342 staining. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of ACAT1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of ACAT1 expression in HeLa (A), HEK293T (B), SP2/0 (C), H9C2 (D), THP1 (E) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Goat Un-conjugated ELISA, WB Antibody (0.1µg/ml) staining of Mouse (A) and Rat (B) Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Goat Un-conjugated ELISA, WB Western Blot: ACAT1 Antibody [NBP1-51994] - Analysis of Mouse (A) and Rat (B) kidney lysates, and Mouse (C) and Rat (D) Liver lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: ACAT1 Antibody [NBP1-51994] - (0.01ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: ACAT1 Antibody [NBP1-89285] - Lane 1: Marker [kDa] 230, 110, 82, 49, 32, 26, 18.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunohistochemistry-Paraffin: ACAT1 Antibody [NBP1-89285] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 34 Days
$491.63
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2/Jurkat/293/A549 cells, using ACAT1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ACAT1 Pab (ABIN391807) in SK-BR-3 cell line lysates (35 µg/lane).ACAT1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ACAT1 antibody (C-term) (ABIN391807), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details

ACAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ACAT1 Antibodies

  1. Hamster Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN152908 : Chang, Chen, Thomas, Cheng, Del Priore, Newton, Pape, Chang: Regulation and immunolocalization of acyl-coenzyme A: cholesterol acyltransferase in mammalian cells as studied with specific antibodies. in The Journal of biological chemistry 1996 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN4277536 : Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN4277537 : Sanchez-Alvarez, Martinez-Outschoorn, Lin, Lamb, Hulit, Howell, Sotgia, Rubin, Lisanti: Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. in Cell cycle (Georgetown, Tex.) 2013 (PubMed)
    Show all 3 Pubmed References

  4. Polyclonal ACAT1 Primary Antibody for IP, WB - ABIN540796 : Song, Kost, Martin: Androgens augment renal vascular responses to ANG II in New Zealand genetically hypertensive rats. in American journal of physiology. Regulatory, integrative and comparative physiology 2006 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ACAT1 Primary Antibody for ELISA, WB - ABIN4277535 : Hongo, Watanabe, Arita, Kanome, Kageyama, Shioda, Miyazaki: Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages. in American journal of physiology. Endocrinology and metabolism 2009 (PubMed)

More Antibodies against ACAT1 Interaction Partners

Human Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. ACAT1 exonic mutations that affect ESE sequences may result in aberrant splicing. This may affect the activity of mitochondrial acetoacetyl-CoA thiolase.

  2. compound heterozygous of ACAT1 gene mutations probably underlie the beta-ketothiolase deficiency in our patient

  3. Data indicate that acetyl-CoA (show LPCAT2 Antibodies) acetyltransferase (ACAT1) and malate dehydrogenase (MDH2 (show MDH Antibodies)) are involved in various drug-resistance-forming mechanisms.

  4. ACAT1, ACACA (show ACACA Antibodies), ALDH6A1 (show ALDH6A1 Antibodies) and MTHFD1 (show MTHFD1 Antibodies) represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals.

  5. the pyruvate dehydrogenase (show PDP Antibodies) complex is regulated by Tyr (show TYR Antibodies) phosphorylation of PDP1 (show PDP Antibodies), which toggles recruitment between ACAT1 and SIRT3 (show SIRT3 Antibodies)

  6. these findings indicate that ACAT1 expression could serve as a potential prognostic marker in prostate cancer, specifically in differentiating indolent and aggressive forms of cancer.

  7. ACAT1 expression is substantially elevated in human castration-resistant metastatic prostate cancer tissues.

  8. Data show that the ketone body metabolizing enzymes BDH1 (show BDH1 Antibodies), BDH2 (show BDH2 Antibodies), OXCT1 (show OXCT1 Antibodies) and ACAT1 were expressed at the mRNA and protein level in all glioma cell lines.

  9. Crystallographic and kinetic studies were made on mitochondrial acetyl-CoA (show LPCAT2 Antibodies) thiolase (show HADHB Antibodies): the importance of potassium and chloride ions were noted for its structure and function.

  10. I/D polymorphism of ACE (show ACE Antibodies) gene and AC AT1 (show AGTR1 Antibodies) gene influence the development of hypertension and Left Ventricular Hypertrophy in Hemodialysis patients.

Mouse (Murine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. Data show that microRNA miR (show MLXIP Antibodies)-467b regulates the acetyl-CoA acetyltransferase 1 (ACAT1) expression via targeting ACAT1 (show SOAT1 Antibodies) 3' untranslated regions (3'UTR (show UTS2R Antibodies)).

  2. In a mouse model, targeting ACAT1 (show SOAT1 Antibodies) specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages.

  3. Oxidized low-density lipoprotein activated the TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)/NF-kappaB (show NFKB1 Antibodies) inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 (show SOAT1 Antibodies) expression and promotes VSMC foam cell formation.

  4. Exacerbation of liver fibrosis by ACAT1 (show SOAT1 Antibodies) deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 (show TLR4 Antibodies) signaling.

  5. ACAT1 (show SOAT1 Antibodies) plays important roles in hematopoiesis in normal mouse and in Apoe (show APOE Antibodies)(-/-) mouse during atherosclerosis development.

  6. ApoA-I (show APOA1 Antibodies) Helsinki promotes accumulation of ACAT1 (show SOAT1 Antibodies) in a mouse macrophage cell line.

  7. the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT (show SOAT1 Antibodies) inhibition in addition to potent inhibition of macrophage ACAT-1 (show SOAT1 Antibodies)

  8. ACAT1 (show SOAT1 Antibodies) gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease.

  9. ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol

  10. ACAT1 (show SOAT1 Antibodies) knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1.

Cow (Bovine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. The transcript abundance of ACAT1 was increased in the more efficient low residual feed intake (RFI (show RNF34 Antibodies)) animals and decreased in the less efficient high RFI (show RNF34 Antibodies) animals

ACAT1 Antigen Profile

Protein Summary

This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

Gene names and symbols associated with ACAT1

  • acetyl-CoA acetyltransferase 1 (ACAT1) antibody
  • acetyl-CoA acetyltransferase 1 (Acat1) antibody
  • acetyl-Coenzyme A acetyltransferase 1 (Acat1) antibody
  • acetyl-CoA acetyltransferase 1 (acat1) antibody
  • acetyl-CoA acetyltransferase 1 L homeolog (acat1.L) antibody
  • 6330585C21Rik antibody
  • Acat antibody
  • acat1-a antibody
  • fd16h07 antibody
  • fd20g06 antibody
  • MAT antibody
  • RATACAL antibody
  • T2 antibody
  • THIL antibody
  • wu:fd16h07 antibody
  • wu:fd20g06 antibody
  • zgc:86832 antibody

Protein level used designations for ACAT1

acetoacetyl Coenzyme A thiolase , acetoacetyl-CoA thiolase , acetyl-CoA acetyltransferase, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 , mitochondrial acetoacetyl-CoA thiolase , acetyl-Co A acetyltransferase 1 mitochondrial , acetyl-coenzyme A acetyltransferase 1 , acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) , acetyl-CoA acetyltransferase 1 , Acetoacetyl-CoA thiolase A , acetyl-CoA acetyltransferase A, mitochondrial

GENE ID SPECIES
38 Homo sapiens
25014 Rattus norvegicus
110446 Mus musculus
418968 Gallus gallus
445290 Danio rerio
489421 Canis lupus familiaris
511082 Bos taurus
100597123 Nomascus leucogenys
100626793 Sus scrofa
414639 Xenopus laevis
100717423 Cavia porcellus
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