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ACAT1 encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Additionally we are shipping ACAT1 Kits (18) and ACAT1 Proteins (13) and many more products for this protein.
Showing 10 out of 163 products:
Hamster Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN152908
Chang, Chen, Thomas, Cheng, Del Priore, Newton, Pape, Chang: Regulation and immunolocalization of acyl-coenzyme A: cholesterol acyltransferase in mammalian cells as studied with specific antibodies. in The Journal of biological chemistry 1996
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Human Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN4277536
Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012
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Human Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN4277537
Sanchez-Alvarez, Martinez-Outschoorn, Lin, Lamb, Hulit, Howell, Sotgia, Rubin, Lisanti: Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. in Cell cycle (Georgetown, Tex.) 2013
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Human Polyclonal ACAT1 Primary Antibody for ELISA, WB - ABIN4277535
Hongo, Watanabe, Arita, Kanome, Kageyama, Shioda, Miyazaki: Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages. in American journal of physiology. Endocrinology and metabolism 2009
Polyclonal ACAT1 Primary Antibody for IP, WB - ABIN540796
Song, Kost, Martin: Androgens augment renal vascular responses to ANG II in New Zealand genetically hypertensive rats. in American journal of physiology. Regulatory, integrative and comparative physiology 2006
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Our results demonstrated the contrasting effects of STC1 (show STC1 Antibodies) and STC2 (show STC2 Antibodies)-derived peptides on human macrophage foam cell formation associated with ACAT1 expression and on HASMC migration.
these results illustrate that ACAT1-catalyzed esterification of 24S-OHC with long-chain unsaturated fatty acid followed by formation of atypical LD-like structures at the ER membrane is a critical requirement for 24S-OHC-induced cell death.
ACAT1 exonic mutations that affect ESE sequences may result in aberrant splicing. This may affect the activity of mitochondrial acetoacetyl-CoA thiolase.
TLR4 (show TLR4 Antibodies) siRNA inhibits cell proliferation, migration and invasion by suppressing ACAT1 expression, suggesting that TLR4 (show TLR4 Antibodies) may be a potential therapeutic target for the treatment of colorectal cancer
ACAT1 has a role in regulating the dynamics of free cholesterols in plasma membrane which leads to the APP (show APP Antibodies)-alpha-processing alteration
compound heterozygous of ACAT1 gene mutations probably underlie the beta-ketothiolase deficiency in our patient
ACAT1 regulates glioblastoma-cell proliferation via modification of the Akt and/or the ERK1/2 pathway.
Data indicate that acetyl-CoA (show LPCAT2 Antibodies) acetyltransferase (ACAT1) and malate dehydrogenase (MDH2 (show MDH Antibodies)) are involved in various drug-resistance-forming mechanisms.
ACAT1, ACACA (show ACACA Antibodies), ALDH6A1 (show ALDH6A1 Antibodies) and MTHFD1 (show MTHFD1 Antibodies) represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals.
Data show that the C allele of acyl-CoA (show GNPAT Antibodies) acyltransferase-1 (ACAT-1) rs1044925 was associated with a decreased risk of coronary artery disease and ischemic stroke patients.
Data show that microRNA miR (show MLXIP Antibodies)-467b regulates the acetyl-CoA acetyltransferase 1 (ACAT1) expression via targeting ACAT1 (show SOAT1 Antibodies) 3' untranslated regions (3'UTR (show UTS2R Antibodies)).
In a mouse model, targeting ACAT1 (show SOAT1 Antibodies) specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages.
Oxidized low-density lipoprotein activated the TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)/NF-kappaB (show NFKB1 Antibodies) inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 (show SOAT1 Antibodies) expression and promotes VSMC foam cell formation.
Exacerbation of liver fibrosis by ACAT1 (show SOAT1 Antibodies) deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 (show TLR4 Antibodies) signaling.
ACAT1 (show SOAT1 Antibodies) plays important roles in hematopoiesis in normal mouse and in Apoe (show APOE Antibodies)(-/-) mouse during atherosclerosis development.
ApoA-I (show APOA1 Antibodies) Helsinki promotes accumulation of ACAT1 (show SOAT1 Antibodies) in a mouse macrophage cell line.
the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT (show SOAT1 Antibodies) inhibition in addition to potent inhibition of macrophage ACAT-1 (show SOAT1 Antibodies)
ACAT1 (show SOAT1 Antibodies) gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease.
ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol
ACAT1 (show SOAT1 Antibodies) knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1.
The transcript abundance of ACAT1 was increased in the more efficient low residual feed intake (RFI (show RNF34 Antibodies)) animals and decreased in the less efficient high RFI (show RNF34 Antibodies) animals
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
acetoacetyl Coenzyme A thiolase
, acetoacetyl-CoA thiolase
, acetyl-CoA acetyltransferase, mitochondrial
, acetyl-Coenzyme A acetyltransferase 1
, mitochondrial acetoacetyl-CoA thiolase
, acetyl-Co A acetyltransferase 1 mitochondrial
, acetyl-coenzyme A acetyltransferase 1
, acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
, acetyl-CoA acetyltransferase 1
, Acetoacetyl-CoA thiolase A
, acetyl-CoA acetyltransferase A, mitochondrial