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ACAT1 Products

(Acetyl-CoA Acetyltransferase 1 (ACAT1))
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009].

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Featured ACAT1 Categories

ACAT1 Antibodies

High quality antibodies with extensive validation data.

ACAT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ACAT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ACAT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (8)
Cat. No. ABIN7256768
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN6136413
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (7)
Cat. No. ABIN6136414
Quantity 100 μL
Datasheet Datasheet

Recommended ACAT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964523
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960676
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674860
Quantity 96 tests
Datasheet Datasheet

Recommended ACAT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121639
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305610
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305612
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ACAT1 products

Hai, Ritchey, Robinet, Alzayed, Brubaker, Zhang, Smith: "Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 1, pp. 83-91, (2019) (PubMed).

Mulye, Zapata, Gilk: "Altering lipid droplet homeostasis affects Coxiella burnetii intracellular growth." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192215, (2018) (PubMed).

Saadane, Mast, Dao, Ahmad, Pikuleva: "Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells." in: The Journal of biological chemistry, Vol. 291, Issue 39, pp. 20427-39, (2016) (PubMed).

Sanchez-Alvarez, Martinez-Outschoorn, Lin, Lamb, Hulit, Howell, Sotgia, Rubin, Lisanti: "Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention." in: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 2, pp. 289-301, (2013) (PubMed).

Bhathena, Martoni, Kulamarva, Tomaro-Duchesneau, Malhotra, Paul, Urbanska, Prakash: "Oral probiotic microcapsule formulation ameliorates non-alcoholic fatty liver disease in Bio F1B Golden Syrian hamsters." in: PLoS ONE, Vol. 8, Issue 3, pp. e58394, (2013) (PubMed).

Chang, Olson, Schwartz: "Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy." in: Nutrition & metabolism, Vol. 10, Issue 1, pp. 47, (2013) (PubMed).

Andersson, Konrad, Ashok, Pontén, Hober, Asplund: "Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 11, pp. 773-84, (2013) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Martinez-Outschoorn, Lin, Whitaker-Menezes, Howell, Lisanti, Sotgia: "Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 21, pp. 3956-63, (2012) (PubMed).

Martinez-Outschoorn, Lin, Whitaker-Menezes, Howell, Sotgia, Lisanti: "Ketone body utilization drives tumor growth and metastasis." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 21, pp. 3964-71, (2012) (PubMed).

Synonyms and alternative names related to ACAT1

acetyl-CoA acetyltransferase 1 (ACAT1), acetyl-CoA acetyltransferase 1 (Acat1), acetyl-Coenzyme A acetyltransferase 1 (Acat1), acetyl-CoA acetyltransferase 1 (acat1), acetyl-CoA acetyltransferase 1 L homeolog (acat1.L), 6330585C21Rik, ACAT, Acat, acat1-a, fd16h07, fd20g06, MAT, RATACAL, T2, THIL, wu:fd16h07, wu:fd20g06, zgc:86832

Protein level used designations for ACAT1

  • acetoacetyl Coenzyme A thiolase
  • acetoacetyl-CoA thiolase
  • acetyl-CoA acetyltransferase, mitochondrial
  • acetyl-Coenzyme A acetyltransferase 1
  • mitochondrial acetoacetyl-CoA thiolase
  • acetyl-Co A acetyltransferase 1 mitochondrial
  • acetyl-coenzyme A acetyltransferase 1
  • acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
  • acetyl-CoA acetyltransferase 1
  • Acetoacetyl-CoA thiolase A
  • acetyl-CoA acetyltransferase A, mitochondrial
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