anti-Acrosin Binding Protein (ACRBP) Antibodies

The protein encoded by ACRBP is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. Additionally we are shipping Acrosin Binding Protein Kits (7) and Acrosin Binding Protein Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACRBP 84519 Q8NEB7
Anti-Rat ACRBP ACRBP 500316 Q6AY33
Anti-Mouse ACRBP ACRBP 54137 Q3V140
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Top anti-Acrosin Binding Protein Antibodies at

Showing 10 out of 29 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: ACRBP Sample Tissue: Human Hela Whole Cell Antibody Dilution: 1ug/ml 100 μL 2 to 3 Days
Human Rabbit Un-conjugated IC, IF, IP, WB Immunofluorescent analysis of ACRBP staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of ACRBP expression in HEK293T (A), HeLa (B) whole cell lysates. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2/Jurkat/293 cells, using ACRBP Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL 11 to 13 Days
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from 293 cells using ACRBP antibody.The lane on the left is treated with the antigen-specific peptide. ABIN6274429 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 to 12 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293 cells (Lane 1), HepG2 cells (Lane 2) and Jurkat cells (Lane 3 and lane 4), using ACRBP polyclonal antibody . Peptide 100 μg 11 to 12 Days
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining of human testis with ACRBP polyclonal antibody  shows strong cytoplasmic(acrosomal) positivity in cells of seminiferous ducts. Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with ACRBP polyclonal antibody . 100 μL 11 to 12 Days
Human Rabbit Un-conjugated ICC, IF, IP, WB   100 μL 11 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293 cells, HepG2 cells and Jurkat cells, using ACRBP antibody. 100 μg 12 to 14 Days
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL 11 to 14 Days

Top referenced anti-Acrosin Binding Protein Antibodies

  1. Human Polyclonal ACRBP Primary Antibody for ICC, IF - ABIN4277737 : Shetty, Mitchell, Lam, Wu, Zhang, Hill, Tailor, Peters, Penedo, Orwig, Meistrich: Donor spermatogenesis in de novo formed seminiferous tubules from transplanted testicular cells in rhesus monkey testis. in Human reproduction (Oxford, England) 2018 (PubMed)

More Antibodies against Acrosin Binding Protein Interaction Partners

Horse (Equine) Acrosin Binding Protein (ACRBP) interaction partners

  1. ACRBP can be used as a molecular marker for spermatogenesis and sexual maturity in horses.

Human Acrosin Binding Protein (ACRBP) interaction partners

  1. Down regulation of OY-TES-1 increased expression of apoptosis-regulated protein caspase-3, and decreased expression of cell cycle-regulated protein cyclin E, migration/invasion-regulated proteins MMP2 and MMP9.

  2. OY-TES-1 downregulation in liver cancer cells caused 2 opposite effects on cell proliferation: promotion by upregulating CCND2 and CDCA3, and inhibition by CD9 upregulation and NANOG downregulation. OY-TES-1 may play multiple roles in liver cancer.

  3. OY-TES-1 was expressed in ovarian cancer (OC) tissues with a high proportion, and some of OC tissues presented OY-TES-1 expression in high level vs OC adjacent tissues.

  4. OY-TES-1 is frequently expressed in colorectal carcinoma and is able to induce humoral immune response spontaneously in CRC patients.

  5. The down-regulation of OY-TES-1 expression in bone marrow-derived mesenchymal stem cells caused cell growth inhibition, cell cycle arrest, apoptosis induction and migration ability attenuation.

  6. High ACRBP expression correlated with reduced survival time and faster relapse among ovarian cancer patients.

  7. We showed identification of HLA-A24-binding OY-TES-1 peptide, TES(401-409) (KTPFVSPLL) recognized by CD8 T-cells.

Pig (Porcine) Acrosin Binding Protein (ACRBP) interaction partners

  1. Data show that sperm protein 32 (sp32) expression was higher and significantly higher in capacitated and post-acrosomal reaction sperms than in frozen-thawed sperms and fresh semen, respectively.

Mouse (Murine) Acrosin Binding Protein (ACRBP) interaction partners

  1. Male subfertility of ACRBP-deficient mice may be attributed to incompleteness of the acrosome reaction rather than impairment in sperm migration from the uterus to the oviduct.

  2. Setd2 deficiency results in complete loss of H3K36me3 and significantly decreases expression of thousands of genes, including those encoding acrosin-binding protein 1 (Acrbp1) and protamines, required for spermatogenesis.

  3. ACRBP-null male mice showed a severely reduced fertility, because of malformation of the acrosome.

  4. Two forms of Acrbp mRNA-wild-type Acrbp-W and variant Acrbp-V5 mRNAs-were generated by alternative splicing of Acrbp in the mouse.

  5. Data suggest that the fertility defect in PCSK4 (proprotein convertase subtilisin/kexin type 4) knockout mice is due, in part, to altered processing/proteolysis of ACRBP as well as structural abnormalities in sperm heads and acrosomes.

Acrosin Binding Protein (ACRBP) Antigen Profile

Protein Summary

The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon.

Gene names and symbols associated with ACRBP

  • acrosin binding protein (ACRBP) antibody
  • acrosin binding protein (Acrbp) antibody
  • proacrosin binding protein (Acrbp) antibody
  • ACRBP antibody
  • CT23 antibody
  • OY-TES-1 antibody
  • sp32 antibody

Protein level used designations for ACRBP

acrosin binding protein , proacrosin binding protein sp32 , acrosin-binding protein-like , acrosin-binding protein , cancer/testis antigen 23 , cancer/testis antigen OY-TES-1 , proacrosin binding protein , proacrosin-binding protein sp32 , Acrosin-binding protein , proacrosin-binding protein (sp32) , sp32

451789 Pan troglodytes
713219 Macaca mulatta
100052268 Equus caballus
100338899 Oryctolagus cuniculus
100403575 Callithrix jacchus
477713 Canis lupus familiaris
84519 Homo sapiens
500316 Rattus norvegicus
397317 Sus scrofa
54137 Mus musculus
100135468 Cavia porcellus
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