Activity-Regulated Cytoskeleton-Associated Protein Proteins (Arc)

Plays a role in the regulation of cell morphology and cytoskeletal organization. Additionally we are shipping Arc Antibodies (43) and Arc Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Arc 11838 Q9WV31
Arc 23237 Q7LC44
Arc 54323 Q63053
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Top Arc Proteins at

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Escherichia coli (E. coli) Mouse His tag   50 μg Log in to see 13 to 16 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 13 to 16 Days
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days

Arc Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

Rat (Rattus) ,

More Proteins for Activity-Regulated Cytoskeleton-Associated Protein (Arc) Interaction Partners

Mouse (Murine) Activity-Regulated Cytoskeleton-Associated Protein (Arc) interaction partners

  1. Specific acetylation of lysine residues on Arc (show NOL3 Proteins) promote Arc (show NOL3 Proteins) protein stability.

  2. Stress from escapable electroshock (ES) was associated with up-regulation of brain-derived neurotrophic factor (show BDNF Proteins) in amygdala as well as medial prefrontal cortex (mPFC). Stres from inescapable shock suppressed c-fos in mPFC (0 h) but induced more Arc (show NOL3 Proteins) in amygdala (2 h) in comparison with ES.

  3. Our data support the hypothesis that the kinetics of Arc (show NOL3 Proteins) induction to refine cortical representations of sensory categories is sensitive to the familiarity of the sensory experience.

  4. PSD95 (show DLG4 Proteins) was essential for Arc (show NOL3 Proteins) assembly into 1.5-MDa complexes and activity-dependent recruitment to excitatory synapses.

  5. Data show that although activity-dependent expression of activity regulated cytoskeletal-associated protein (Arc) mRNA does not change with age, expression of Arc (show NOL3 Proteins) protein is maximal during the critical period and declines in adulthood.

  6. It appears that palmitoylation regulates at least a subset of Arc (show NOL3 Proteins) functions in synaptic plasticity.

  7. These results indicate that dopamine is required to drive activity-dependent amplification of Arc (show NOL3 Proteins) mRNA in the developing postnatal frontal cortex.

  8. Study demonstrates in mice that explored novel spatial environments, the involvement of Egr3 (show EGR3 Proteins) in regulating the late protein-dependent phase of Arc (show NOL3 Proteins) expression in the dentate gyrus.

  9. Arc/Arg3.1 effects on memory formation are not only manifested at the level of molecular pathways regulating synaptic plasticity, but also at the systems level.

  10. CTCF (show CTCF Proteins) knockdown attenuates fear-conditioning-induced hippocampal gene expression of key learning genes and loss of long-range interactions at the BDNF (show BDNF Proteins) and Arc (show NOL3 Proteins) loci.

Human Activity-Regulated Cytoskeleton-Associated Protein (Arc) interaction partners

  1. The ARC (show NOL3 Proteins) complex revealed association with verbal and total IQ in child.

  2. Study identified several rare mutations that reduced ARC (show NOL3 Proteins) expression in schizophrenia patients. Furthermore, DNA methylation (show HELLS Proteins) of ARC (show NOL3 Proteins) in schizophrenia patients may be associated with a downregulation of ARC (show NOL3 Proteins) mRNA expression. These findings suggest that multiple rare ARC (show NOL3 Proteins) variants and DNA methylation (show HELLS Proteins) of ARC (show NOL3 Proteins) might contribute to the pathogenesis of schizophrenia.

  3. missense mutations in TRIAD3 abolished the interaction of TRIAD3A with Arc (show NOL3 Proteins), disrupting Arc (show NOL3 Proteins) ubiquitination, and consequently Arc (show NOL3 Proteins) degradation.

  4. ARC (show NOL3 Proteins) confers resistance to sunitinib in renal cell carcinoma (show MOK Proteins) through alternate angiogenesis pathways

  5. We tested whether ARC (show NOL3 Proteins) variants are associated with six measures of cognitive functioning in 670 healthy subjects in the Norwegian Cognitive NeuroGenetics (NCNG) by extracting data from its Genome-Wide Association Study (GWAS).

  6. this is the first report associating an ARC (show NOL3 Proteins) SNP with schizophrenia and supports recent large-scale GWAS findings implicating the ARC (show NOL3 Proteins) complex in schizophrenia risk

  7. we propose that the peculiar characteristics of Arc (show NOL3 Proteins) protein, such as its optimal expression after ongoing experience or familiar behavior could explain how familiarization and recognition memories are stored and preserved in the mammalian brain--{REVIEW}

  8. mRNA levels of ARC (show NOL3 Proteins) and SGK1 (show SGK1 Proteins) did not differ significantly between the schizophrenia or control samples.

  9. Arc (show NOL3 Proteins) is a flexible multi-domain protein that exists in monomeric and oligomeric forms, compatible with a diverse, hub-like role in plasticity-related processes.

  10. Degradation of Arc (show NOL3 Proteins) by clathrin-localized Triad3A regulates the availability of synaptic AMPA (show GRIA3 Proteins) receptors.

Arc Protein Profile

Protein Summary

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration (By similarity). Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.

Gene names and symbols associated with Arc

  • activity regulated cytoskeleton associated protein (ARC)
  • activity-regulated cytoskeleton-associated protein (arc)
  • activity regulated cytoskeletal-associated protein (Arc)
  • activity-regulated cytoskeleton-associated protein (Arc)
  • ARC protein
  • Arc3.1 protein
  • ARG3.1 protein
  • C86064 protein
  • mArc protein
  • rg3.1 protein

Protein level used designations for Arc

activity-regulated cytoskeleton-associated protein , activity-regulated cytoskeleton-associated-like protein , ARC/ARG3.1 , activity-regulated gene 3.1 protein homolog , activity regulated cytoskeletal-associated protein , activity-regulated gene 3.1 protein , arg3.1

472874 Pan troglodytes
519403 Bos taurus
752001 Taeniopygia guttata
100271754 Xenopus (Silurana) tropicalis
11838 Mus musculus
23237 Homo sapiens
54323 Rattus norvegicus
395075 Gallus gallus
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