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Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity). Additionally we are shipping ALKBH7 Proteins (5) and ALKBH7 Kits (1) and many more products for this protein.
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Our results uncovered a SNP of ALKBH7, rs7540, which is associated with prostate cancer disease in a statistically significantly manner in two separate cohorts, and maintained in African American men.
ALKBH7 possesses the conserved double-stranded beta-helix fold that coordinates a catalytically active iron by a conserved HX(D/E) em leader Xn em leader H motif.
novel role for a AlkB (show ALKBH Antibodies) homolog, human ALKBH7, in programmed necrosis, presenting a new target for therapeutic intervention in cancer cells that are resistant to apoptotic cell death
results uncover an in vivo role for ALKBH7 in mediating a sexually dimorphic tissue response to alkylation damage that could influence individual responses to chemotherapies based upon alkylating agents.
the first direct demonstration that murine Alkbh7 is a mitochondrial resident protein involved in fatty acid metabolism and the development of obesity.
Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).
alkylated DNA repair protein alkB homolog 7
, alpha-ketoglutarate-dependent dioxygenase alkB homolog 7
, probable alpha-ketoglutarate-dependent dioxygenase ABH7
, spermatogenesis associated 11
, spermatogenesis cell proliferation related protein
, spermatogenesis cell proliferation-related protein
, spermatogenesis-associated protein 11