anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) Antibodies

The protein encoded by APBA3 is a member of the APBB protein family. Additionally we are shipping Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APBA3 57267 O88888
APBA3 9546 O96018
APBA3 83611 O70248
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Top anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-APBA3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, using APBA3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6274839 staining HuvEc by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis of extracts from HUVEC cells, using APBA3 antibody.The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB APBA3 Antibody (Center)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the APBA3 antibody detected the APBA3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Mouse Rabbit Un-conjugated WB Figure 1 illustrates Western blot detection of Mint3 from AtT20 cell extract using ABIN267155. Western Blot: APBA3/Mint-3 Antibody [ABIN267155] - Analysis of Mint3 from AtT20 cell extract. 0.1 mg Log in to see 7 to 9 Days
$444.19
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Lane 1: mouse spleen lysates Lane 2: mouse brain lysates probed with Anti APBA3/Mint3/X11 gamma Polyclonal Antibody, Unconjugated (ABIN1385696) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 63kD. Observed band size: 63kD. 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated WB Western blot analysis in NCI-H292 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details

More Antibodies against Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Interaction Partners

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) interaction partners

  1. APBA3-deficient mice show reduced metastasis, with no apparent effect on primary tumor growth. APBA3 deficiency in inflammatory monocytes hampers glycolysis-dependent chemotaxis of cells toward metastatic sites.

  2. we have identified Mint3 as a physiological positive regulator of TLR3 (show TLR3 Antibodies)/4 and RIG-I (show DDX58 Antibodies)-induced IFN-beta (show IFNB1 Antibodies) production and have outlined a feedback mechanism for the control of antiviral immune responses.

  3. Mint3 depletion attenuated metastasis to the lungs in breast cancer model mice.

  4. Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock.

  5. Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase (show MMP16 Antibodies), MT5-MMP (show MMP24 Antibodies), to the plasma membrane by binding to its carboxyl end motif EWV

  6. Binding of Munc18-1 (show STXBP1 Antibodies) to closed, target-SNARE (show VTI1B Antibodies) syntaxin 1 (show STX1A Antibodies) stimulates vesicle docking and regulates the consecutive priming step during exocytosis of secretory or synaptic vesicles.

  7. X11L2 functions in the nucleus by a mechanism distinct from conventional transactivators

Human Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) interaction partners

  1. Results suggest that NECAB3 (show NECAB3 Antibodies), a novel Mint3-binding protein, activates HIF-1 (show HIF1A Antibodies) to promote normoxic glycolysis and tumorigenicity by forming a ternary complex with Mint3 and FIH-1 (show HIF1AN Antibodies).

  2. FIH-1 (show HIF1AN Antibodies)-Mint3 axis does not control HIF-1 (show HIF1A Antibodies) transcriptional activity in nucleus pulposus cells.

  3. Mints are necessary for activity-induced APP (show APP Antibodies) and PS1 (show PSEN1 Antibodies) trafficking and provide insight into the cellular fate of APP (show APP Antibodies) in endocytic pathways essential for Abeta (show APP Antibodies) production.

  4. Strict specificity for recruitment of the Mint3 adaptor by APP (show APP Antibodies) at the Golgi, a critical role for Tyr (show TYR Antibodies)-682 (within the YENPTY motif) in Mint3 recruitment and export of APP (show APP Antibodies) from the Golgi, are demonstrated.

  5. These results indicate that all three amyloid beta protein precursor family members are capable of activating gene transcription via Mint3-Taz (show TAZ Antibodies) and Mint3-Yap (show YAP1 Antibodies).

  6. Two transcriptional coactivators, TAZ (show TAZ Antibodies) and YAP (show YAP1 Antibodies), functionally associate with amyloid precursor protein (show APP Antibodies) through Mint3 and form transcriptionally active triple protein complexes.

  7. Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase (show MMP16 Antibodies), MT5-MMP (show MMP24 Antibodies), to the plasma membrane by binding to its carboxyl end motif EWV

  8. We have examined the ability of Bcr (show BCR Antibodies) to interact with other epithelial PDZ (show INADL Antibodies) proteins and found specific binding to both the apical PDZK1 (show PDZK1 Antibodies) protein and the Golgi-localized Mint3

  9. These data implicate Mint3 activity as a critical determinant of post-Golgi APP (show APP Antibodies) traffic.

  10. the interaction between the PTB (show PTBP1 Antibodies) domain of Mint3 and the acidic peptide signal of Furin (show FURIN Antibodies) regulates the specific localization of Furin (show FURIN Antibodies) in the trans-Golgi network

Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.

Gene names and symbols associated with APBA3

  • amyloid beta precursor protein binding family A member 3 (APBA3) antibody
  • amyloid beta (A4) precursor protein-binding, family A, member 3 (Apba3) antibody
  • amyloid beta precursor protein binding family A member 3 (Apba3) antibody
  • AW208791 antibody
  • lin-10 antibody
  • MGC:15815 antibody
  • Mint-3 antibody
  • Mint3 antibody
  • X11gamma antibody
  • X11L2 antibody

Protein level used designations for APBA3

amyloid beta (A4) precursor protein-binding, family A, member 3 , Mint 3 , adapter protein X11gamma , amyloid beta A4 precursor protein-binding family A member 3 , neuron-specific X11L2 protein , neuronal munc18-1-interacting protein 3 , X11-like 2 protein , amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) , mint-3 , phosphotyrosine-binding/-interacting domain (PTB)-bearing protein , amyloid beta (A4) precursor protein-binding family A member 3 (X11-like 2) , amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) , neuronal Munc18-1-interacting protein 3

GENE ID SPECIES
100021747 Monodelphis domestica
57267 Mus musculus
9546 Homo sapiens
485053 Canis lupus familiaris
83611 Rattus norvegicus
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