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APH1A Antibodies

(Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein.
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Internal Region) antibody anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Internal Region) antibody anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Internal Region) antibody [ABIN190762]

Verified APH1A Reactivity: Human ELISA, IHC, WB Host: Goat Polyclonal unconjugated

anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 71-170) antibody anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 71-170) antibody anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 71-170) antibody [ABIN706016]

APH1A Reactivity: Human, Mouse, Rat ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Middle Region) antibody anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Middle Region) antibody anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Middle Region) antibody [ABIN1030864]

APH1A Reactivity: Human, Mouse, Rat IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

APH1A Antibodies by Grade

Find APH1A Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Reactivity

Find APH1A Antibodies for a variety of species such as anti-Human APH1A, anti-Mouse APH1A, anti-Rat APH1A. The species listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Application

Find APH1A Antibodies validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

APH1A Antibodies by Host

Find APH1A Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Binding Specificity

Find APH1A Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Clonality

Find available monoclonal or polyclonal APH1A Antibodies. Click on a link to go to the corresponding products.

APH1A Antibodies by Clone

Find APH1A Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Conjugate

Find APH1A Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APH1A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • collections(2)
Cat. No. ABIN6656109
Quantity 100 μg
Reactivity Human
Application IHC (p), WB
Validations
  • collections(2)
Cat. No. ABIN390272
Quantity 400 μL
Reactivity Human, Mouse, Rat
Application EIA, IHC (p), WB
Validations
  • collections(2)
Cat. No. ABIN499309
Quantity 0.1 mg
Reactivity Human
Application WB
Validations
  • collections(1)
Cat. No. ABIN5027035
Quantity 100 μg
Reactivity Mouse
Application WB
Validations
  • collections(1)
Cat. No. ABIN1539365
Quantity 400 μL
Reactivity Cow, Dog, Horse, Human, Monkey, Opossum
Application WB
Validations
  • collections(1)
Cat. No. ABIN960079
Quantity 100 μg
Reactivity Human, Mouse
Application EIA, WB
Validations
  • collections(1)
Cat. No. ABIN499307
Quantity 0.1 mg
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • collections(1)
Cat. No. ABIN1731860
Quantity 50 μg
Reactivity Human, Mouse
Application IF
Validations
Cat. No. ABIN7008818
Quantity 60 μL
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7153562
Quantity 100 μg
Reactivity Human
Application ELISA, IF
Validations
Cat. No. ABIN7153559
Quantity 100 μg
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7153560
Quantity 100 μg
Reactivity Human
Application
Validations
Cat. No. ABIN7153561
Quantity 100 μg
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
Cat. No. ABIN1842033
Quantity 100 μL
Reactivity Human, Mouse
Application ELISA, WB
Validations
Cat. No. ABIN6990699
Quantity 0.1 mg

Latest Publications on our APH1A Antibodies

Area-Gomez, de Groof, Boldogh, Bird, Gibson, Koehler, Yu, Duff, Yaffe, Pon, Schon: "Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria." in: The American journal of pathology, Vol. 175, Issue 5, pp. 1810-6, (2009) (PubMed).

Spasic, Raemaekers, Dillen, Declerck, Baert, Serneels, Füllekrug, Annaert: "Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway." in: The Journal of cell biology, Vol. 176, Issue 5, pp. 629-40, (2007) (PubMed).

Ma, Li, Price, Wong: "APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 1, pp. 192-8, (2005) (PubMed).

Periz, Fortini: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).

Takasugi, Tomita, Hayashi, Tsuruoka, Niimura, Takahashi, Thinakaran, Iwatsubo: "The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).

Marlow, Canet, Haugabook, Hardy, Lahiri, Sambamurti: "APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity." in: Biochemical and biophysical research communications, Vol. 305, Issue 3, pp. 502-9, (2003) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Gu, Chen, Sanjo, Kawarai, Hasegawa, Duthie, Li, Ruan, Luthra, Mount, Tandon, Fraser, St George-Hyslop: "APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7374-80, (2003) (PubMed).

Goutte, Tsunozaki, Hale, Priess: "APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 775-9, (2002) (PubMed).

Aliases for APH1A Antibodies

aph-1 homolog A, gamma-secretase subunit (APH1A) Antibodies
aph-1 homolog A, gamma secretase subunit L homeolog (aph1a.L) Antibodies
aph-1 homolog A, gamma secretase subunit (Aph1a) Antibodies
anterior pharynx defective 1 homolog A (C. elegans) (APH1A) Antibodies
aph1 homolog A, gamma secretase subunit (Aph1a) Antibodies
acylamino-acid-releasing enzyme-like (LOC100219182) Antibodies
6530402N02Rik Antibodies
APH-1 Antibodies
APH-1A Antibodies
APH-1a Antibodies
CGI-78 Antibodies
RGD1311546 Antibodies
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