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APEX2 Antibodies

(APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012].
APEX2 antibody  (AA 143-171) APEX2 antibody  (AA 143-171) APEX2 antibody (AA 143-171) (ABIN652924)

APEX2 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB23043 unconjugated

APEX2 antibody APEX2 antibody APEX2 antibody (ABIN3003990)

APEX2 Reactivity: Human WB, IHC, FACS, IF/ICC Host: Rabbit Polyclonal unconjugated

APEX2 antibody  (AA 1-518) APEX2 antibody  (AA 1-518) APEX2 antibody (AA 1-518) (ABIN525954)

APEX2 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated

APEX2 Antibodies by Reactivity

Find APEX2 Antibodies for a variety of species such as anti-Human APEX2, anti-Rat APEX2, anti-Mouse APEX2. The species listed below are among those available. Click on a link to go to the corresponding products.

APEX2 Antibodies by Application

Find APEX2 Antibodies validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

APEX2 Antibodies by Host

Find APEX2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

APEX2 Antibodies by Binding Specificity

Find APEX2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APEX2 Antibodies by Clonality

Find available monoclonal or polyclonal APEX2 Antibodies. Click on a link to go to the corresponding products.

APEX2 Antibodies by Clone

Find APEX2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

APEX2 Antibodies by Conjugate

Find APEX2 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APEX2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN652924
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS, IF/ICC
Validations
  • (3)
Cat. No. ABIN3003990
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN525954
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN718481
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB
Validations
  • (1)
Cat. No. ABIN5518737
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
Cat. No. ABIN718483
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718485
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718486
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718487
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN718488
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
Cat. No. ABIN718490
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN882987
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN882986
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN882988
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN882989
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our APEX2 Antibodies

Mengwasser, Adeyemi, Leng, Choi, Clairmont, DAndrea, Elledge: "Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets." in: Molecular cell, Vol. 73, Issue 5, pp. 885-899.e6, (2019) (PubMed).

Karkhanis, Wang, Tae, Hu, Imbalzano, Sif: "Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1." in: The Journal of biological chemistry, Vol. 287, Issue 35, pp. 29801-14, (2012) (PubMed).

Tsuchimoto, Sakai, Sakumi, Nishioka, Sasaki, Fujiwara, Nakabeppu: "Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen." in: Nucleic acids research, Vol. 29, Issue 11, pp. 2349-60, (2001) (PubMed).

Aliases for APEX2 Antibodies

apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2) Antibodies
apurinic/apyrimidinic endodeoxyribonuclease 2 (apex2) Antibodies
APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (apex2) Antibodies
apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog (apex2.L) Antibodies
APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2) Antibodies
apurinic/apyrimidinic endonuclease 2 (Apex2) Antibodies
apurinic/apyrimidinic endodeoxyribonuclease 2 (Apex2) Antibodies
APE2 Antibodies
ape2 Antibodies
APEXL2 Antibodies
apexl2 Antibodies
C430040P13Rik Antibodies
XTH2 Antibodies
xth2 Antibodies
zgc:55889 Antibodies
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