Anaphase Promoting Complex Subunit 15 Proteins (ANAPC15)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Additionally we are shipping Anaphase Promoting Complex Subunit 15 Antibodies (14) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANAPC15 25906 P60006
ANAPC15 505356 Q3SZ31
ANAPC15    
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Top Anaphase Promoting Complex Subunit 15 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,227.64
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,227.64
Details
Escherichia coli (E. coli) Human GST tag 100 μg 11 Days
$356.40
Details
Yeast Cow His tag   1 mg 60 to 71 Days
$2,240.33
Details
Yeast Schizosaccharomyces pombe His tag   1 mg 60 to 71 Days
$2,286.17
Details

ANAPC15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human
,
Cow (Bovine)

Mouse (Murine)

More Proteins for Anaphase Promoting Complex Subunit 15 (ANAPC15) Interaction Partners

Human Anaphase Promoting Complex Subunit 15 (ANAPC15) interaction partners

  1. cryo-EM structure of an APC/C-Cdh1 complex with Apc1(WD40) deleted showed that the mutant APC/C is locked into an inactive conformation in which the UbcH10-binding site of the catalytic module is inaccessible. Additionally, an EM density for Apc15 is not visible

  2. Anaphase promoting complex subunit 15(APC15) mediates the constant turnover of CDC20 and mitotic checkpoint protein complexes, allowing the spindle checkpoint assembly to respond to the attachment state of kinetochores.

  3. APC15 is required for anaphase-promoting complex/cyclosome-bound mitotic checkpoint complex-dependent CDC20 autoubiquitylation and degradation and for timely anaphase initiation.

Anaphase Promoting Complex Subunit 15 (ANAPC15) Protein Profile

Protein Summary

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20.

Gene names and symbols associated with ANAPC15

  • anaphase promoting complex subunit 15 (ANAPC15)
  • APC15 protein
  • C11orf51 protein
  • C15H11orf51 protein

Protein level used designations for ANAPC15

anaphase-promoting complex subunit 15 , protein HSPC020 homolog

GENE ID SPECIES
25906 Homo sapiens
505356 Bos taurus
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