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The protein encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. Additionally we are shipping AMOTL1 Kits (6) and and many more products for this protein.
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Cow (Bovine) Polyclonal AMOTL1 Primary Antibody for WB - ABIN2775636
Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: The LIFEdb database in 2006. in Nucleic acids research 2005
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HECW2 (show HECW2 Antibodies), a novel EC ubiquitin E3 ligase, plays a critical role in stabilizing endothelial cell-to-cell junctions by regulating AMOT (show AMOT Antibodies)-like 1 (AMOTL1) stability.
AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin (show NF2 Antibodies).
phosphorylation-deficient S793Ala mutant of AMOTL1 showed a shorter half-life and conferred resistance to energy-stress-induced YAP (show YAP1 Antibodies) inhibition.
study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP (show CREBBP Antibodies), CBFA2T3 (show CBFA2T3 Antibodies), AMOTL1, FAT4 (show FAT4 Antibodies), FBXO11 (show FBXO11 Antibodies), PLA2G4D, TRRAP (show TRRAP Antibodies) and USH2A (show USH2A Antibodies).
miR (show MLXIP Antibodies)-124 binds AmotL1 3'UTR (show UTS2R Antibodies) and down-regulates its expression repressing vasculogenic mimicry and cell motility in cervical cancer cells.
Scaffold proteins angiomotin (Amot (show AMOT Antibodies)) and angiomotin (show AMOT Antibodies)-related AmotL1 and AmotL2 (show AMOTL2 Antibodies) were recently identified as negative regulators of YAP (show YAP1 Antibodies) and TAZ (show TAZ Antibodies) by preventing their nuclear translocation.
These results suggested that IFN-gamma exhibits anti-angiogenesis effects by regulating the expression of TNF-alpha-induced AmotL1 via NFkappaB in emphysema lungs.
AmotL1 and ZO-2 (show TJP2 Antibodies) are two candidates that could be harnessed to control the oncogenic function of YAP (show YAP1 Antibodies).
By yeast two-hybrid screening, angiomotin-like 1 (AmotL1) was identified as a host factor that interacts with the M protein (show MYOM2 Antibodies) of parainfluenza virus 5 (PIV5).
The angiomotin-like 1 is involved in actin-cytoskeleton-based processes, in part, via its interaction with a p80-angiomotin-containing complex and the actin cytoskeleton
Amot (show AMOT Antibodies) and AmotL1 have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot (show AMOT Antibodies) appears to control the cell polarity and AmotL1 affects the stability of cell-cell junctions.
Amot (show AMOT Antibodies), Amotl1, and Amotl2 (show AMOTL2 Antibodies) are differentially expressed in uterine cells during the peri (show POSTN Antibodies)-implantation period.
Data show that MUPP1 (show MPDZ Antibodies) interacts with angiomotin (Amot (show AMOT Antibodies)), JEAP/Amot (show AMOT Antibodies)-like 1 and MASCOT/Amot (show AMOT Antibodies)-like 2, and that all the Amot (show AMOT Antibodies)/JEAP family proteins also interacted with Patj (show INADL Antibodies), a close relative of MUPP1 (show MPDZ Antibodies).
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
angiomotin like 1
, angiomotin-like protein 1-like
, angiomotin-like protein 1
, junction-enriched and associated protein
, junction-enriched and -associated protein